dc.creatorMazzafera P.
dc.creatorBaumann T.W.
dc.creatorShimizu M.M.
dc.creatorSilvarolla M.B.
dc.date2009
dc.date2015-06-26T13:33:29Z
dc.date2015-11-26T15:32:41Z
dc.date2015-06-26T13:33:29Z
dc.date2015-11-26T15:32:41Z
dc.date.accessioned2018-03-28T22:41:08Z
dc.date.available2018-03-28T22:41:08Z
dc.identifier
dc.identifierTropical Plant Biology. , v. 2, n. 2, p. 63 - 76, 2009.
dc.identifier19359756
dc.identifier10.1007/s12042-009-9032-7
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-70349995868&partnerID=40&md5=e09e5f58b0218536091277c62fa06080
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/91727
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/91727
dc.identifier2-s2.0-70349995868
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1262539
dc.descriptionUnquestionably, the popularity of the coffee beverage relies on its alerting attribute caffeine. However, susceptibilities to this purine alkaloid, quite frequently associated with health concerns, encouraged a significant market for decaffeinated coffee. The beans of Coffea arabica render the best beverage and a decaffeinated coffee has to preserve the desired organoleptic characteristics of this species. Consequently, besides technical removal of caffeine, the endeavors to attain a decaffeinated Arabica coffee range from traditional studies on genetic variability to advanced techniques to produce genetic modified coffee. The aim of this review is to recover part of this subject focusing mainly on the natural genetic variation for caffeine content in Arabica. We also present historical information about caffeine discovery and briefly discuss molecular approaches to reduce caffeine. We introduce here the term decaffito for coffee derived from Arabica plants with beans naturally low in or almost devoid of caffeine. In the near future, coffee drinkers avoiding caffeine will have the choice between basically three Arabica coffees, namely decaffeinated by (a) selection and breeding, (b) genetic modification and (c) industrial extraction. Although only the last decaf coffee is available for the consumers, we believe that the size of the market of each type will occupy in the future depend on the price and health aspects related to the way the decaffeinated coffee beans are obtained. © Springer Science + Business Media, LLC 2009.
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dc.description2
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dc.description76
dc.descriptionAkaffou, D.S., Ky, C.L., Barre, P., Identification and mapping of a major gene (Ft1) involved in fructification time in the interspecific cross Coffea pseudozanguebariae C. liberica var. Dewevrei: Impact on caffeine content and seed weight (2003) Theor Appl Gen, 106, pp. 1486-1490
dc.descriptionAlmeida, J.A.S., Silvarolla, M.B., Fazuoli, L.C., Embriogênese somática em genótipos de Coffea arabica L (2008) Coffee Sci, 3, pp. 143-151
dc.descriptionAlvarez, J.H., Cortina, H.A., Villegas, J.F., Metodo para evaluar antixenosis at Hypothnemus hampei en cafe, bajo condiciones controladas (2002) Cenicafé, 53, pp. 49-59
dc.descriptionAnderson, L., Gibbs, M., The biosynthesis of caffeine in the coffee plant (1962) J Biol Chem, 237, pp. 1941-1944
dc.descriptionAnft B (1937) Friedlieb Ferdinand Runge-sein Leben und sein Werk. Friedrich-Wilhelms-UniversitätAngelucci, E., (1982) Análise química do café, , Campinas: Instituto de Tecnologia de Alimentos
dc.descriptionAnthony, F., Clifford, M.N., Noirot, M., Biochemical diversity in the genus Coffea L.: Chlorogenic acids, caffeine and mozambioside contents (1993) Gen Res Crop Evol, 40, pp. 61-70
dc.descriptionAnthony, F., Bertrand, B., Quiros, O., Genetic diversity of wild coffee (Coffea arabica L.) using molecular markers (2001) Euphytica, 118, pp. 53-65
dc.descriptionAnzueto, F., Bertrand, B., Sarah, J.L., Resistance to Meloidogyne incognita in Ethiopian Coffea arabica accessions (2001) Euphytica, 118, pp. 1-8
dc.descriptionAranda, J.V., Louridas, A.T., Vitullo, B.B., Metabolism of theophylline to caffeine in human fetal liver (1979) Science, 206, pp. 1319-1321
dc.descriptionAshihara, H., Crozier, A., Biosynthesis and catabolism of caffeine in low-caffeine-containing species of Coffea (1999) J Agric Food Chem, 47, pp. 3425-3431
dc.descriptionAshihara, H., Crozier, A., Biosynthesis and metabolism of caffeine and related purine alkaloids in plants (1999) Adv Bot Res, 30, pp. 117-205
dc.descriptionAshihara, H., Crozier, A., Caffeine: A well known but little mentioned compound in plant science (2001) Trends Plant Sci, 6, pp. 407-413
dc.descriptionAshihara, H., Suzuki, T., Distribution and biosynthesis of caffeine in plants (2004) Frontiers Biosci, 9, pp. 1864-1876
dc.descriptionAshihara, H., Sano, H., Crozier, A., Caffeine and related purine alkaloids: Biosynthesis, catabolism, function and genetic engineering (2008) Phytochemistry, 69, pp. 841-856
dc.descriptionAzevedo, A.B.A., Mazzafera, P., Mohamed, R.S., Extraction of caffeine, chlorogenic acids and lipids from green coffee beans using supercritical carbon dioxide and co-solvents (2008) Braz J Chem Eng, 25, pp. 543-552
dc.descriptionBarre, P., Akaffou, S., Louarn, J., Inheritance of caffeine and heteroside contents in an interspecific cross between a cultivated coffee species Coffea liberica var dewevrei and a wild species caffeine-free C. pseudozanguebariae (1998) Theor App Gen, 96, pp. 306-311
dc.descriptionBaumann, T.W., (1987) How microorganisms may help to select coffee beans with desired traits, , Montreux: XII International Conference on Coffee Science
dc.descriptionBaumann, T.W., Some thoughts on the physiology of caffeine in coffee-and a glimpse of metabolic profiling (2006) Braz J Plant Physiol, 18, pp. 243-251
dc.descriptionBaumann, T.W., Dupont-Looser, E., Wanner, H., 7-Methylxanthosine-an intermediate in caffeine biosynthesis (1978) Phytochemistry, 17, pp. 2075-2076
dc.descriptionBaumann, T.W., Koetz, R., Morath, P., N-Methyltransferase activities in suspension cultures of Coffea arabica L (1983) Plant Cell Rep, 2, pp. 33-35
dc.descriptionBayer, C., Fay, M.F., De Bruijn, A.E., Support for an expanded family concept of Malvaceae within a recircumscribed order Malvales: A combined analysis of plastid atpB and rbcL DNA sequences (1999) Bot J Linnean Soc, 129, pp. 267-303
dc.descriptionBegum, B., Hasan, C.M., Rashid, M.A., Caffeine from the mature leaves of Coffea bengalensis (2003) Biochem System Ecol, 31, pp. 1219-1230
dc.descriptionBettencourt, A.J., Rodrigues Jr., C.J., Principles and practice of coffee breeding for resistance to rust and other diseases (1988) Coffee: Agronomy, , R. J. Clarke and R. McRae (Eds.), London: Elsevier Applied Science
dc.descriptionBory, C., Baltassat, P., Porthault, M., Metabolism of theophylline to caffeine in premature newborn-infants (1979) J Pediatr, 94, pp. 988-993
dc.descriptionBravi, F., Bosetti, C., Tavani, A., Coffee drinking and hepatocellular carcinoma risk: A meta analysis (2007) Hepatology, 46, pp. 430-435
dc.descriptionBuchanan, J.M., Hartman, S.C., Enzymatic reactions in the synthesis of purines (1959) Adv Enzymol, 21, pp. 199-261
dc.descriptionBussemas, H.H., Harsch, G., Ettre, L.S., Friedlieb Ferdinand Runge (1794-1867): Self-grown pictures as precursors of paper chromatography (1994) Chromatografia, 38, pp. 243-254
dc.descriptionCadden, I.S.H., Partovi, N., Yoshida, E.M., Review article: Possible beneficial effects of coffee on liver disease and function (2007) Alim Pharmacol Ther, 26, pp. 1-7
dc.descriptionCampa, C., Doulbeau, S., Dussert, S., Diversity in bean caffeine content among wild Coffea species: Evidence of a discontinuous distribution (2005) Food Chem, 91, pp. 633-637
dc.descriptionCarvalho, A., Histórico do desenvolvimento do cultivo do café no Brasil (1993) Documentos IAC, 34, pp. 1-7
dc.descriptionCarvalho, A., Fazuoli, L.C., Café (1993) O Melhoramento de Plantas no Instituto Agronômico, , 1, A. M. C. Furlani, G. P. Viégas (Eds.), Campinas: Instituto Agronômico, Secretaria da Agricultura de São Paulo
dc.descriptionCarvalho, A., Monaco, L.C., Genetic relationships of selected Coffea species (1967) Ciên Cult, 19, pp. 151-165
dc.descriptionCarvalho, A., Tango, J.S., Monaco, L.C., Genetic control of the caffeine content of coffee (1965) Nature, 205, p. 314
dc.descriptionCarvalho A, Fazuoli LC, Levy FA et al (1983a). Observações sobre característica dos frutos de introduções da Etiópia. X Congresso Brasileiro de Pesquisas Cafeeiras, Poços de Caldas (MG), resumos, pp 90-92Carvalho, A., Sondähl, M.R., Sloman, C., (1983) Teor de cafeína em seleções de café, , Poços de Caldas: X Congresso Brasileiro de Pesquisas Cafeeiras
dc.descriptionCarvalho, A., Fazuoli, L.C., Mazzafera, P., Melhoramento do cafeeiro. XIII. Produtividade de populações derivadas da hibridação dos cultivares Laurina e Mundo Novo de C. arabica (1988) Bragantia, 47, pp. 213-222
dc.descriptionCarvalho, A., Medina, H.P., Filho, F.L.C., Aspectos genéticos do cafeeiro (1991) Rev bras Genet, 14, pp. 135-183
dc.descriptionCastillo-Zapata, J., Parra-Hernández, J., Exploración en el contenido de cafeína, grasas y sólidos solubles en 113 "introduciones" de cafe (1973) Cenicafé, 24, pp. 3-22
dc.descriptionhttp://www.teaandcoffee.net/0302/coffee.htm, Castle TJ (2002) Decaf dialogue. Tea Coffee Trade J online 176Chang, J., Gotcher, S., Gushaw, J.B., Homogeneous enzyme immunoassay for theophylline in serum and plasma (1982) Clin Chem, 28, pp. 361-367
dc.descriptionCharrier, A., (1978) La structure génétique des caféiers spontanés de la région Malgache (Mascarocoffea). Leurs relations avec les caféiers d'origine africaine (Eucoffea), , Paris: ORSTOM
dc.descriptionCharrier, A., Berthaud, J., Variation de la teneur en caféine dans le genre Coffea (1975) Café Cacao Thé, 19, pp. 251-264
dc.descriptionCharrier, A., Berthaud, J., Botanical classification of coffee (1985) Coffee: Botany, biochemistry and production of beans end beverage, , M. N. Clifford and K. C. Wilson (Eds.), Westport: Avi
dc.descriptionChen, H.W., Zenobi, R., Direct analysis of living objects by extractive electrospray mass ionization spectrometry (2007) Chimia, 61, pp. 843-843
dc.descriptionChen, H.W., Sun, Y.P., Wortmann, A., Differentiation of maturity and quality of fruit using noninvasive extractive electrospray ionization quadrupole time-of-flight mass spectrometry (2007) Anal Chem, 79, pp. 1447-1455
dc.descriptionChevalier A (1947) Les caféiers du globe, fasc. 3: systématique des caféiers et faux-caféiers, maladies et insectes nuisibles. ParisClifford, M.N., Williams, T., Bridson, D., Chlorogenic acids and caffeine as possible taxonomic criteria in Coffea and Psilanthus (1989) Phytochemistry, 28, pp. 829-838
dc.descriptionClifford, M.N., Gibson, C.L., Rakotomalala, J.-J., Caffeine from green beans of Mascarocoffea (1991) Phytochemistry, 30, pp. 4039-4040
dc.descriptionCrepet, W.L., Nixon, K.C., Gandolfo, M.A., Fossil evidence and phylogeny: The age of major angiosperm clades based from mesofossil and macrofossil evidence from Creataceous deposits (2004) Am J Bot, 91, pp. 1666-1682
dc.descriptionDaly, J.W., Caffeine analogs: Biomedical impact (2007) Cell Mol Life Sci, 64, pp. 2153-2169
dc.descriptionDavis, A.P., Govaerts, R., Bridson, D.M., AnAn annotated taxonomic conspectus of the genus Coffea (Rubiaceae) (2006) Bot J Linn Soc, 152, pp. 465-512
dc.descriptionde Araujo, E.F., de Queiroz, L.P., Machado, M.A., What is citrus? Taxonomic implications from a study of cp-DNA evolution in the tribe Citreae (Rutaceae subfamily Aurantioideae) (2003) Organ Diver Evol, 3, pp. 55-62
dc.descriptionDórea, J.G., Costa, T.H.M., Is coffee a functional food? (2005) Br J Nutr, 93, pp. 773-782
dc.descriptionDuarte, C., Sur leurs teneurs en eau et en caféine des cafés de iles de S. Tomé et du Prince (1930) Anais Inst Sup Agron Portugal, 4, pp. 20-27
dc.descriptionDucruix A, Pascard-Billy C, Hammoniere M et al (1975) X-ray structure of mascaroside, a new bitter glycoside from coffee beans. J Chem Soc, Chem Commun 396Fischer, E., Ueber die Constitution des Caffeïns, Xanthins, Hypoxanthins und verwandter Basen (1897) Ber d deutsch chem Gesellschaft, 30, pp. 549-559
dc.descriptionFischer, E., Ach, L., Synthese des Caffeïns (1895) Ber d deutsch chem Gesellschaft, 28, pp. 3135-3143
dc.descriptionFredholm, B.B., Caffeine as an adenosine receptor antagonist (2004) Eur Neuropsychopharmacol, 14, pp. S156-S157
dc.descriptionFredholm, B.B., Bättig, K., Holmén, J., Actions of caffeine in the brain with special reference to factors that contribute to its widespread use (1999) Pharmacol Rev, 51, pp. 83-133
dc.descriptionFrischknecht, P.M., Baumann, T.W., The pattern of purine alkaloid formation in suspension cultures of Coffea arabica (1980) Planta Medica, 40, pp. 245-249
dc.descriptionGeraets, L., Moonen, H.J.J., Wouters, E.F.M., Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations (2006) Biochem Pharmacol, 72, pp. 902-910
dc.descriptionGeromel, C., Ferreira, L.P., Cavalari, A.A., Biochemical and genomic analysis of sucrose metabolism during coffee (Coffea arabica) fruit development (2006) J Exp Bot, 57, pp. 3243-3258
dc.descriptionGuerreiro Filho, O., Mazzafera, P., Caffeine and resistance of coffee to the berry borer Hypothenemus hampei (Coleoptera: Scolytidae) (2003) J Agric Food Chem, 51, pp. 6987-6991
dc.descriptionGushaw, J.B., Hu, M.W., Miller, J.G., Homogeneous enzyme immunoassay for theophylline in serum (1977) Clin Chem, 23, p. 1144. , (Abstract)
dc.descriptionHammer, K., Arrowsmith, N., Gladis, T., Agrobiodiversity with emphasis on plant genetic resources (2003) Naturrwissenschaften, 90, pp. 241-250
dc.descriptionHarmsen, M.M., De Haard, H.J., Properties, production, and applications of camelid single-domain antibody fragments (2007) Appl Microbiol Biotechnol, 77, pp. 13-22
dc.descriptionHeilmann, W., Decaffeination of coffee (2001) Coffee recent developments, , R. J. Clarke and O. G. Vitzthum (Eds.), Oxford, UK: Blackwell Sciences
dc.descriptionHein, L., Gatzweiler, F., The economic value of coffee (Coffea arabica) genetic resources (2006) Ecol Econ, 60, pp. 176-185
dc.descriptionHelgeson, C., Hu, M.W.K.C., A homogeneous enzyme-immunoassay for caffeine in serum (1983) Clin Chem, 29, p. 1275. , (Abstract)
dc.descriptionHigdon, J.V., Frei, B., Coffee and health: A review of recent human research (2006) Crit Rev Food Sci Nutr, 46, pp. 101-123
dc.descriptionHolscher, W., Rohkaffeebehandlung im Verbraucherland (2005) Kaffee-Die Zukunft, , J. B. Rothfos and H. Lange (Eds.), Hamburg: Behr's Verlag
dc.descriptionInoue, T., Adachi, F., Studies on biogenesis of tea components. III. The origin of the methylgroups in caffeine (1962) Chem Pharm Bull, 10, pp. 1212-1214
dc.descriptionhttp://www.teaandcoffee.net/0903/world.htm, Jones HC (2003) Brazil decaf market survey unveiled. Tea Coffee Trade J online 177Kato, M., Mizuno, K., Caffeine synthase and related methyltransferases in plants (2004) Frontiers Biosci, 9, pp. 1833-1842
dc.descriptionKato, M., Mizuno, K., Fujimura, T., Purification and characterization of caffeine synthase from tea leaves (1999) Plant Physiol, 120, pp. 579-586
dc.descriptionKato, M., Mizuno, K., Crozier, A., Caffeine synthase gene from tea leaves (2000) Nature, 406, pp. 956-957
dc.descriptionKatz, S.N., Decaffeination of coffee (1985) Coffee, , 2, R. J. Clarke and R. Macrae (Eds.), London: Technology, Elsevier Applied Science
dc.descriptionKremers, R.E., Speculation on DPN as a biochemical precursor of caffeine and trigonelline in coffee (1954) J Am Pharm Assoc, 43, pp. 423-424
dc.descriptionKrug, C.A., Mendes, J.E.T., Carvalho, A., Taxonomia de Coffea arabica L.: Descrição de variedades e formas encontradas no Estado de São Paulo (1938) Bol Inst Agronom Campinas, 62, pp. 1-57
dc.descriptionKushalappa, A.C., Eskes, A.B., Advances in coffee rust research (1989) Annu Rev Phytopathol, 27, pp. 503-531
dc.descriptionKy, C.L., Louarn, J., Dussert, S., Caffeine, trigonelline, chlorogenic acid and sucrose diversity in wild Coffea arabica L. and C. canephora P. accessions (2001) Food Chem, 75, pp. 223-230
dc.descriptionLadenson, R.C., Crimmins, D.L., Landt, Y., Isolation and characterization of a thermally stable recombinant anti-caffeine heavy-chain antibody fragment (2006) Anal Chem, 78, pp. 4501-4508
dc.descriptionLarsson, S.C., Wolk, A., Coffee consumption and risk of liver cancer: A meta-analysis (2007) Gastroenterology, 132, pp. 1740-1745
dc.descriptionLashermes, P., Combes, M.-C., Robert, J., Molecular characterisation and origin of the Coffea arabica L. genome (1999) Mol Gen Genet, 261, pp. 259-266
dc.descriptionLe Pierres, D., (1987) Influence des facteurs génétiques sur le contrôle de la teneur en caféine du café, , Montreux: XII Colloquiun Scientifique International sur la Chimie du Café
dc.descriptionLeroy, T., Montagnon, C., Charrier, A., Reciprocal recorrent selection applied to Coffea canephora Pierre. I: Characterization and evaluation of breeding populations and value of intergroup hybrids (1993) Euphytica, 67, pp. 113-125
dc.descriptionLin, C., Mueller, L.A., McCarthy, J., Coffee and tomato share common gene repertoires as revealed by deep sequencing of seed and cherry transcripts (2005) Theor Appl Genet, 112, pp. 114-130
dc.descriptionLooser, E., Baumann, T.W., Wanner, H., The biosynthesis of caffeine on the coffee plant (1974) Phytochemistry, 13, pp. 2515-2518
dc.descriptionLove, B., Spaner, D., Agrobiodiversity: Its value, measurement and conservation in the context of sustainable agriculture (2007) J Sustain Agric, 31, pp. 53-82
dc.descriptionMahé, L., Combes, M.-C., Lashermes, P., Comparison between a coffee single copy chromosomal region and Arabidopsis duplicated counterparts evidenced high level synteny between the coffee genome and the ancestral Arabidopsis genome (2007) Plant Mol Biol, 64, pp. 699-711
dc.descriptionMascitelli, L., Pezzetta, F., Sullivan, J.L., Putative hepatoprotective effects of coffee (2008) Aliment Pharmacol Ther, 27, pp. 90-92
dc.descriptionMaurin, O., Davis, A.P., Chester, M., Towards a phylogeny for Coffea (Rubiaceae): Identifying well-supported lineages based on nuclear and plastid DNA sequences (2007) Ann Bot, 100, pp. 1565-1583
dc.descriptionMazzafera, P., Catabolism of caffeine in plants and microorganisms (2004) Frontiers Biosci, 9, pp. 1348-1359
dc.descriptionMazzafera, P., Carvalho, A., A cafeína do café (1991) Documentos IAC, 25, pp. 1-22
dc.descriptionMazzafera, P., Carvalho, A., Breeding for low seed caffeine content of coffee (Coffea L.) by interspecific hybridization (1992) Euphytica, 59, pp. 55-60
dc.descriptionMazzafera, P., Braghini, M.T., Eskes, A.B., (1985) Indications on the ocurrence of male sterility in Coffea canephora and C. arabica, , Lomé, Togo: XI International Conference on Coffee Science
dc.descriptionMazzafera, P., Carvalho, A., Fazuoli, L.C., Variabilidade do teor de cafeína em sementes de café (1992) Turrialba, 42, pp. 231-237
dc.descriptionMazzafera, P., Crozier, A., Sandberg, G., Studies on the metabolic control of caffeine turnover in developing endosperms and leaves of Coffea arabica and Coffea dewevrei (1994) J Agric Food Chem, 42, p. 1423
dc.descriptionMazzafera, P., Wingsle, G., Olsson, O., S-adenosyl-L-methionine: Theobromine 1-N-methyltransferase, an enzyme catalyzing the synthesis of caffeine in coffee (1994) Phytochemistry, 37, pp. 1577-1584
dc.descriptionMcCarthy, A.A., McCarthy, J.G., The structure of two N-methyltransferases from the caffeine biosynthetic pathway (2007) Plant Physiol, 144, pp. 879-889
dc.descriptionMcCarthy, A.A., Biget, L., Lin, C., Cloning, expression, crystallization and preliminary X-ray analysis of the XMT and DXMT N-methyltransferases from Coffea canephora (robusta) (2007) Acta Cryst, F63, pp. 304-307
dc.descriptionMedicus, L., Zur Constitution der Harnsäuregruppe (1875) Annalen der Pharmacie, 175, pp. 230-251
dc.descriptionMedina Filho, H.P., Carvalho, A., Söndahl, M.R., Coffee breeding and related evolutionary aspects (1984) Plant breeding reviews, , 2, J. Janick (Ed.), Westport: Avi
dc.descriptionMontagnon, C., Guyot, B., Cilas, C., Genetic parameters of several biochemical compounds from green coffee, Coffea canephora (1998) Plant Breed, 117, pp. 576-578
dc.descriptionMösli Waldhauser, S.S., Baumann, T.W., Compartmentation of caffeine and related purine alkaloids depends exclusively on the physical chemistry of their vacuolar complex formation with chlorogenic acids (1996) Phytochemistry, 42, pp. 985-996
dc.descriptionMueller, L.A., Solow, T.H., Taylor, N., The SOL genomics network: A comparative resource for Solanaceae biology and beyond (2005) Plant Physiol, 138, pp. 1310-1317
dc.descriptionNagai, C., Rakotomalala, J.J., Katahira, R., Production of a new low-caffeine hybrid coffee and the biochemical mechanism of low caffeine accumulation (2008) Euphytica, 164, pp. 133-142
dc.descriptionNatarajan, G., Botica, M.-L., Thomas, R., Therapeutic drug monitoring for caffeine in preterm neonates: An unnecessary exercise? (2007) Pediatrics, 119, pp. 936-940
dc.description(http://www.ncausa.org), National_Coffee_Association (2006) U.S. coffee consumptionNegishi, O., Ozawa, T., Imagawa, H., Conversion of xanthosine into caffeine in tea plants (1985) Agric Biol Chem, 49, pp. 251-253
dc.descriptionNegishi, O., Ozawa, T., Imagawa, H., Methylation of xanthosine by tea-leaf extracts and caffeine biosynthesis (1985) Agric Biol Chem, 49, pp. 887-890
dc.descriptionNegishi, O., Ozawa, T., Imagawa, H., N-methyl nucleosidase from tea leaves (1988) Agric Biol Chem, 52, pp. 169-175
dc.descriptionNegishi, O., Ozawa, T., Imagawa, H., Guanosine deaminase and guanine deaminase from tea leaves (1994) Biosci Biotech Biochem, 58, pp. 1277-1281
dc.descriptionOgawa, M., Herai, Y., Koizumi, N., 7-Methylxanthine methyltransferase of coffee plants (2001) J Biol Chem, 276, pp. 8213-8218
dc.descriptionOgita, S., Uefuji, H., Yamaguchi, Y., Producing decaffeinated coffee plants (2003) Nature, 423, pp. 823-823
dc.descriptionOgita, S., Uefuji, H., Morimoto, M., Application of RNAi to confirm theobromine as the major intermediate for caffeine biosynthesis in coffee plants with potential for construction of decaffeinated varieties (2004) Plant Mol Biol, 54, pp. 931-941
dc.descriptionOgita, S., Uefuji, H., Morimoto, M., Metabolic engineering of caffeine production (2005) Plant Biotechnol, 22, pp. 461-468
dc.descriptionOgutuga, D.B.A., Northcote, D.H., Biosynthesis of caffeine in tea callus tissue (1970) Biochem J, 117, pp. 715-720
dc.descriptionOken L (1820) Rezension zu Runges 'Neueste phytochemische Entdeckungen'. Isis: 334-336(http://www.iac.sp.gov.br/PosIAC/Entrada.htm), Oliveira MPA (2007) Expressão de genes da biossíntese de cafeína em frutos e endospermas de Coffea arabica: sem cafeína. MSc, Instituto Agronômico de CampinasOu, C.-N., Fraeley, V.L., Ellis, J.M., Evaluation of the EMIT reagent system for measurement of caffeine with the EMIT lab 5000 system and a centrifugal analyzer (1984) Clin Chem, 30, pp. 887-889
dc.descriptionPacher, P., Szabo, C., Role of Poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: The therapeutic potential of PARP inhibitors (2007) Cardiovasc Drug Rev, 25, pp. 235-260
dc.descriptionPatil, P.S., Mallath, M.K., Coffee and hepatocellular carcinoma: Cause or confounding? (2007) Hepatology, 46, pp. 2046-2047
dc.descriptionPelletier, J., Note sur la caféine, Lue à l'Academie royale de médecine (1826) J Pharmacie 12e Année, 5, pp. 229-233
dc.descriptionPfaff, C.H., Liebig, J., Über die Zusammensetzung des Kaffeins (1832) Annalen der Pharmacie, 1, pp. 17-20
dc.descriptionPreusser, E., Serenkov, G.P., Caffeine biosynthesis in tea leaves (1963) Biokhimiya, 28, pp. 857-861
dc.descriptionPrewo, R., Guggisberg, A., Lorenzi-Riatsch, A., Crystal structure of mozambioside, a diterpene glycoside of Coffea pseudozanguebariae (1990) Phytochemistry, 29, pp. 990-992
dc.descriptionPriolli, R.H.G., Mazzafera, P., Siqueira, W.J., Caffeine inheritance in interspecific hybrids of Coffea arabica x Coffea canephor (Gentianales, Rubiaceae) (2008) Gen Mol Biol, 31, pp. 498-504
dc.descriptionRakotomalala JJR (1992) Diversité biochimique des caféiers: Analyse des acides hydroxycinnamiques, bases puriques et diterpènes glycosidiques. Particularités des caféiers sauvages de la région malgache (Mascarocoffea Chev.). Ph.D., Universite Montpellier IIRakotomalala, J.-J.R., Cros, E., Clifford, M.N., Caffeine and theobromine in green beans from Mascarocoffea (1992) Phytochemistry, 31, pp. 1271-1272
dc.descriptionRakotomalala, J.-J.R., Kumamoto, T., Aburatani, T., (2004) Caffeine content distribution among Mascarocoffea species in Madagascar, , Bangalore: 20th International Conference on Coffee Science
dc.descriptionRamalakshmi, K., Raghavan, B., Caffeine in coffee: Its removal. Why and how? (1999) Crit Rev Food Sci Nutr, 39, pp. 441-456
dc.descriptionRoberts, M.F., Waller, G.R., N-methyltransferases and 7-methyl-N9-nucleoside hydrolase activity in Coffea arabica and the biosynthesis of caffeine (1979) Phytochemistry, 18, pp. 451-455
dc.descriptionRunge, F.F., (1819) De nova methodo veneficium belladonnae, daturae nec non hyoscyami explorandi. Dissertation inaug, , Jena: Jenae
dc.descriptionRunge FF (1820a) Anleitung zu einer besseren Zerlegungsweise der Vegetabilien durch Theorie und Versuche. In: Runge FF (eds) Neueste phytochemische Entdeckungen zur Begründung einer wissenschaftlichen Phytochemie, BerlinRunge FF (1820b) Über Pflanzenchemie (Fortsetzung). Isis: 329-333Salmona, J., Dussert, S., Descroix, F., Deciphering transcroptional networks that govern Coffea arabica seed development using combined cDNA array and real time RT-PCR approaches (2008) Plant Mol Biol, 66, pp. 105-124
dc.descriptionScholthof, K., The disease triangle: Pathogens, the environment and society (2007) Nature Rev Microbiol, 5, pp. 152-156
dc.descriptionSchulthess, B.H., Baumann, T.W., Are xanthosine and 7-methylxanthosine caffeine precursors? (1995) Phytochemistry, 39, pp. 1363-1370
dc.descriptionSchulthess, B.H., Baumann, T.W., Stimulation of caffeine biosynthesis in suspension-cultured coffee cells and the in situ existence of 7-methylxanthosine (1995) Phytochemistry, 38, pp. 1381-1386
dc.descriptionSchulthess, B.H., Morath, P., Baumann, T.W., Caffeine biosynthesis starts with the metabolically-channelled formation of 7-methyl-XMP-a new hypothesis (1996) Phytochemistry, 41, pp. 169-175
dc.descriptionShlonsky, A.K., Klatsky, A.L., Armstrong, M.A., Traits of persons who drink decaffeinated coffee (2003) Ann Epidemiol, 13, pp. 273-279
dc.descriptionSilvarolla, M.B., Mazzafera, P., Lima, M.M.A., Caffeine content of Ethiopian Coffea arabica beans (2000) Gen Mol Biol, 23, pp. 213-215
dc.descriptionSilvarolla, M.B., Mazzafera, P., Fazuoli, L.C., A naturally decaffeinated arabica coffee (2004) Nature, 429, pp. 826-826
dc.descriptionSilvarolla, M.B., Fazuoli, L.C., Mazzafera, P., A obtenção de um café naturalmente descafeinado (2007) O Agronômico, 59, pp. 60-62
dc.descriptionSnyder, S.H., Katims, J.J., Annau, Z., Adenosine receptors and behavioral actions of methylxanthines (1981) Proc Natl Acad Sci USA, 78, pp. 3260-3264
dc.descriptionSöndahl, M.R., Lauritis, J.A., Coffee (1992) Biotechnology of perennial fruit crops, , F. A. Hammerschlag and R. E. Litz (Eds.), Cambridge: CAB International
dc.descriptionSöndahl, M.R., Nakamura, T., Filho, H.P.M., Coffee (1984) Handbook of Plant Cell Culture, , 3, P. V. Ammirato, D. A. Evans, W. R. Sharp, and Y. Yamada (Eds.), New York: Crop Sciences, Macmillan
dc.descriptionSuzuki, T., Takahashi, E., Biosynthesis of caffeine by tea-leaf extracts. Enzymic formation of theobromine from 7-methylxanthine and of caffeine from theobromine (1975) Biochem J, 146, pp. 87-96
dc.descriptionSuzuki, T., Takahashi, E., Caffeine biosynthesis in Camellia sinensis (1976) Phytochemistry, 15, pp. 1235-1239
dc.descriptionSuzuki, T., Waller, G.R., Biosynthesis and biodegradation of caffeine, theobromine, and theophylline in Coffea arabica L. fruits (1984) J Agric Food Chem, 32, pp. 845-848
dc.descriptionSzabo, C., Pacher, P., Swanson, R.A., Novel modulators of poly(ADP-ribose) polymerase (2006) Trends Pharmacol Sci, 27 (12), pp. 626-630
dc.descriptionTaketa, A.T.C., Breitmaier, E., Schenkel, E.P., Triterpenes and triterpenoidal glycosides from the fruits of Ilex prarguariensis (Maté) (2004) J Braz Chem Soc, 15, pp. 205-211
dc.descriptionTang, H., Bowers, J.E., Wang, X., Synteny and collinearity in plant genomes (2008) Science, 320, pp. 486-488
dc.descriptionTango, J.S., Teixeira, G.C., Teor de cafeína em progênies de café (1961) Bol Super Serv Café, 36, pp. 6-10
dc.descriptionTanksley, S.D., McCouch, S.R., Seed banks and molecular maps unlocking genetic potential from the wild (1997) Science, 277, pp. 1063-1066
dc.descriptiontenKate, K., Laird, S.A., Introduction (2000) The commercial use of biodiversity: Access to genetic resources and benefit-sharing, , K. tenKate and S. A. Laird (Eds.), London: Earthscan
dc.descriptionUsmani, O.S., Belvisi, M.G., Patel, H.J., Crispino, N., Birrell, M.A., Korbonits, M., Korbonits, D., Barnes, P.J., Theobromine inhibits sensory nerve activation and cough (2004) Faseb J, 18, pp. 231-247
dc.descriptionvan Dam, R.M., Hu, F.B., Coffee consumption and risk of type 2 diabetes (2005) JAMA, 294, pp. 97-104
dc.descriptionVitória, A.P., Mazzafera, P., Xanthine degradation and related enzymes activities in leaves and fruits of two Coffea species differing in caffeine catabolism (1999) J Agric Food Chem, 47, pp. 1851-1855
dc.descriptionVitzthum, O.G., Chemie und Bearbeitung des Kaffees (1976) Kaffee und Coffein, pp. 3-64. , 2, O. Eichler (Ed.), Berlin: Springer
dc.descriptionWaldhauser, S.S.M., Gillies, F.M., Crozier, A., Separation of the N-7 methyltransferase, the key enzyme in caffeine biosynthesis (1997) Phytochemistry, 45, pp. 1407-1414
dc.descriptionWaldhauser, S.S.M., Kretschmar, J.A., Baumann, T.W., N-methyltransferase activities in caffeine biosynthesis: Biochemical characterization and time-course during leaf development of Coffea arabica (1997) Phytochemistry, 44, pp. 853-859
dc.descriptionWilbaux, R., Recherches sur la préparation du café par voie humide (1938) Serie Technique - INEAC, 21, pp. 1-45
dc.descriptionWu, F., Mueller, L.A., Crouzillat, D., Combining bioinformatics und phylogenetics to identify large sets of single-copy orthologous genes (COSII) for comparative, evolutionary and systematic studies: A test case in the Euasterid plant clade (2006) Genetics, 174, pp. 1407-1420
dc.descriptionYoneyama, N., Morimoto, H., Ye, C.-X., Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme (2006) Mol Gen Genom, 275, pp. 125-135
dc.descriptionZaprometov, M.N., Formation of caffeine in tea plant shoots (1962) Biokhimiya, 27, pp. 679-684
dc.descriptionZosel, K., Praktische Anwendungen der Stofftrennung mit überkritischen Gasen (1978) Angewandte Chemie, 90, pp. 748-755
dc.languageen
dc.publisher
dc.relationTropical Plant Biology
dc.rightsfechado
dc.sourceScopus
dc.titleDecaf And The Steeplechase Towards Decaffito-the Coffee From Caffeine-free Arabica Plants
dc.typeArtículos de revistas


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