The Inclusion Of New Techniques Of Chromosome Analysis Has Improved The Cytogenetic Profile Of Turner Syndrome [a Inclusão De Novas Técnicas De Análise Citogenética Aperfeiçoou O Diagnóstico Cromossômico Da Síndrome De Turner]

dc.creatorBarros B.A.
dc.creatorMaciel-Guerra A.T.
dc.creatorde Mello M.P.
dc.creatorCoeli F.B.
dc.creatorde Carvalho A.B.
dc.creatorViguetti-Campos N.
dc.creatorde Godoy Assumpcao J.
dc.creatorMarques-de-Faria A.P.
dc.creatorde Lemos-Marini S.H.L.
dc.creatorGuerra-Junior G.
dc.date2009
dc.date2015-06-26T13:32:20Z
dc.date2015-11-26T15:29:06Z
dc.date2015-06-26T13:32:20Z
dc.date2015-11-26T15:29:06Z
dc.date.accessioned2018-03-28T22:37:50Z
dc.date.available2018-03-28T22:37:50Z
dc.identifier
dc.identifierArquivos Brasileiros De Endocrinologia E Metabologia. , v. 53, n. 9, p. 1137 - 1142, 2009.
dc.identifier42730
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-77049112045&partnerID=40&md5=508319280b647e3a9dbd44d8e7ff83f9
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/91538
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/91538
dc.identifier2-s2.0-77049112045
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1261760
dc.descriptionObjective: To evaluate the effect of the improvement of chromosome analysis on the cytoge- netic findings of Turner syndrome (TS) patients. Methods: Retrospective study of the results of the karyotypes of 260 patients with TS, regarding banding techniques, number of cells analyzed and results of investigation of Y-chromosome sequences. According to karyotype, divided in 45,X; sex chromosome mosaicism without Y; structural aberrations of sex chromosomes with or without mosaicism; sex chromosome mosaicism with Y. Results: 45,X was the most frequent karyotype (108), followed by structural aberrations (88) and mosaics (58 without Y and 6 with Y). Introduction of banding techniques and increase in the number of cells analyzed resulted in progressive decrease of 45,X karyotype and increase of structural aberrations. The study of Y- chromosome sequences was performed in 96 cases of which 10 resulted positive. Conclusions: Improvement of chromosome analysis over the years has modified the cytogenetic profile of TS.
dc.description53
dc.description9
dc.description1137
dc.description1142
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dc.languagept
dc.publisher
dc.relationArquivos Brasileiros de Endocrinologia e Metabologia
dc.rightsaberto
dc.sourceScopus
dc.titleThe Inclusion Of New Techniques Of Chromosome Analysis Has Improved The Cytogenetic Profile Of Turner Syndrome [a Inclusão De Novas Técnicas De Análise Citogenética Aperfeiçoou O Diagnóstico Cromossômico Da Síndrome De Turner]
dc.typeArtículos de revistas


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