dc.creatorFerreira R.C.
dc.creatorWard L.S.
dc.creatorAdam R.L.
dc.creatorLeite N.J.
dc.creatorMetze K.
dc.creatorde Matos P.S.
dc.date2009
dc.date2015-06-26T13:32:22Z
dc.date2015-11-26T15:28:55Z
dc.date2015-06-26T13:32:22Z
dc.date2015-11-26T15:28:55Z
dc.date.accessioned2018-03-28T22:37:39Z
dc.date.available2018-03-28T22:37:39Z
dc.identifier
dc.identifierArquivos Brasileiros De Endocrinologia E Metabologia. , v. 53, n. 7, p. 804 - 810, 2009.
dc.identifier42730
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-70749121769&partnerID=40&md5=afc7b2664c69ac698f28687b60a05f4b
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/91542
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/91542
dc.identifier2-s2.0-70749121769
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1261723
dc.descriptionObjective and methods: To investigate the utility of nuclear chromatin texture assessment in the differential diagnosis of follicular patterned lesions, by means of examining 76 samples previously submitted to the immunohistochemical protein analysis of HBME-1, CK-19 and galectina-3. Results: HBME-1 confirmed to be the most sensitive marker of malignancy. A series of morphometric, densitometric and texture variables were useful in the discrimination of the different types of follicular lesions. Among these variables, r2, a parameter related to the granularity of the nucleus presented the best accuracy, sensitivity, specificity and positive and negative predictive values, distinguishing benign from malignant lesions. Conclusion: The morphometric analysis of nuclear chromatin images may add accuracy to the differential diagnosis of follicular patterned lesions.
dc.description53
dc.description7
dc.description804
dc.description810
dc.descriptionFranc, B., de la Salmonière, P., Lange, F., Hoang, C., Louvel, A., de Roquancourt, A., Interobserver and intraobserver reproducibility in the histopathology of follicular thyroid carcinoma (2003) Hum Pathol, 34 (11), pp. 1092-100
dc.descriptionWard, L.S., Valente, H.O.F., de Araujo, P.P.C., Tincani, A.J., Assumpcão, L.V.M., Commonly used prognostic scoring systems are not adequate to predict the outcome of papillary microcarcinomas of the thyroid (2008) Pediatric Blood & Cancer, 50 (6), pp. 1288-9
dc.descriptionFagin, J.A., Ward, L.S., Kimura, E.T., Câncer de tireóide: Passado, presente e futuro (2007) Arq Bras Endocrinol Metab, 51 (5), pp. 641-2
dc.descriptionCerutti, J.M., Nodule diagnosed as follicular patterned lesion: Are biomarkers the promise? (2007) Arq Bras Endocrinol Metabol, 51 (5), pp. 832-42
dc.descriptionMeyer, E.L.S., Wagner, M.S., Maia, A.L., Iodothyronine deiodinases expression in thyroid neoplasias (2007) Arq Bras Endocrinol Metabol, 51 (5), pp. 690-700
dc.descriptionBartolazzi, A., Gasbarri, A., Papotti, M., Bussolat, G., Lucante, T., Khan, A., Thyroid Cancer Study Group. Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions (2001) Lancet, 357 (9269), pp. 1644-50
dc.descriptionMartins, L., Matsuo, S.E., Ebina, K.N., Kulcsar, M.A., Friguglietti, C.V., Kimura, E.T., Galectin-3 messenger ribonucleic acid and protein are expressed in benign thyroid tumors (2002) J Clin Endocrinol Metab, 87 (8), pp. 4806-10
dc.descriptionFeilchenfeldt, J., Totsch, M., Sheu, S.Y., Robert, J., Spiliopoulos, A., Frilling, A., Expression of galectin-3 in normal and malignant thyroid tissue by quantitative PCR and immunohistochemistry (2003) Mod Pathol, 16 (11), pp. 1117-23
dc.descriptionJakubiak-Wielganowicz, M., Kubiak, R., Sygut, J., Pomorski, L., Kordek, R., Usefulness of galectin-3 immunohistochemistry in differential diagnosis between thyroid follicular carcinoma and follicular adenoma (2003) Pol J Pathol, 54 (2), pp. 111-5
dc.descriptionMiettinen, M., Karkkainen, P., Differential reactivity of HBME-1 and CD15 antibodies in benign and malignant thyroid tumours. Preferential reactivity with malignant tumours (1996) Virchows Arch, 429 (4-5), pp. 213-9
dc.descriptionSack, M.J., Astengo-Osuna, C., Lin, B.T., Battifora, H., Livolsi, V.A., HBME-1 immunostaining in thyroid fine-needle aspirations: A useful marker in the diagnosis of carcinoma (1997) Mod Pathol, 10 (7), pp. 668-74
dc.descriptionMai, K.T., Bokhary, R., Yazdi, H.M., Thomas, J., Commons, A.S., Reduced HBME-1 immunoreactivity of papillary thyroid carcinoma and papillary thyroid carcinoma-related neoplastic lesions with Hurthle cell and/or apocrine-like changes (2002) Histopathology, 40 (2), pp. 133-42
dc.descriptionBeesley, M.F., McLaren, K.M., Cytokeratin 19 and galectin-3 immunohistochemistry in the differential diagnosis of solitary thyroid nodules (2002) Histopathology, 41 (3), pp. 236-43
dc.descriptionMatos, P.S., Ferreira, A.P., de Oliveira Facuri, F., Assumpção, L.V., Metze, K., Ward, L.S., Usefulness of HBME-1, cytokeratin 19 and galectin-3 immunostaining in the diagnosis of thyroid malignancy (2005) Histopathology, 47 (4), pp. 391-401
dc.descriptionAsa, S.L., The role of immunohistochemical markers in the diagnosis of follicular-patterned lesions of the thyroid (2005) Endocr Pathol, 16 (4), pp. 295-309
dc.descriptionFerreira, R.C., Matos, P.S., Adam, R.L., Leite, N.L., Metze, K., Application of the Minkowski-Bouligand fractal dimension for the differential diagnosis of thyroid follicular neoplasias (2006) Cell Oncol, 28 (56), pp. 331-3
dc.descriptionMetze, K., Adam, R.L., Silva, P.V., Carvalho, R.B., Leite, N.J., Analysis of chromatin texture by Pinkus' approximate entropy (2004) Cytometry Part A, 59 A, p. 63
dc.descriptionOberholzer, M., Heitz, P.U., Kloppel, G., Ehrsam, R.E., Morphometry in endocrine pathology (1984) Pathol Res Pract, 179 (2), pp. 220-4
dc.descriptionMurata, S., Mochizuki, K., Nakazawa, T., Kondo, T., Nakamura, N., Yamashita, H., Morphological abstraction of thyroid tumor cell nuclei using morphometry with factor analysis (2003) Microsc Res Tech, 61 (5), pp. 457-62
dc.descriptionGupta, N., Sarkar, C., Singh, R., Karak, A.K., Evaluation of diagnostic efficiency of computerized image analysis based quantitative nuclear parameters in papillary and follicular thyroid tumors using paraffin-embedded tissue sections (2001) Pathol Oncol Res, 7 (1), pp. 46-55
dc.descriptionWouver, G.V.D., Weyn, B., Scheunders, P., Jacob, W., Marck, E.V., Dyck, D.V., Wavelets as chromatin texture descriptors for the automated identification of neoplastic nuclei (2000) J Microsc, 197 (Pt 1), pp. 25-35
dc.descriptionShaposhnikov, V.M., Combined morphologic criteria in the diagnosis of thyroid diseases (1991) Arkh Patol, 53 (1), pp. 23-7
dc.descriptionMello, M.R., Metze, K., Adam, R.L., Pereira, F.G., Magalhães, M.G., Machado, C.G., Phenotypic subtypes of acute lymphoblastic leukemia associated with different nuclear chromatin texture (2008) Anal Quant Cytol Histol, 30 (2), pp. 92-8
dc.descriptionMetze, K., Ferreira, R.C., Adam, R.L., Leite, N.J., Ward, L.S., de Matos, P.S., Chromatin texture is size dependent in follicular adenomas but not in hyperplastic nodules of the thyroid (2008) World J Surg, 32 (12), pp. 2744-6
dc.descriptionKayser, K., Kayser, G., Metze, K., The concept of structural entropy in tissue-based diagnosis (2007) Anal Quant Cytol Histol, 29 (5), pp. 296-308
dc.descriptionAuada, M.P., Adam, R.L., Leite, N.J., Puzzi, M.B., Cintra, M.L., Rizzo, W.B., Anal Quant Cytol Histol. Texture analysis of the epidermis based on fast Fourier transformation in Sjögren-Larsson syndrome (2006) Cytol Histol, 28 (4), pp. 219-27
dc.descriptionDoudkine, A., Macaulay, C., Poulin, N., Palcic, B., Nuclear texture measurements in image cytometry (1995) Pathologica, 87 (3), pp. 286-99
dc.descriptionHirokawa, M., Carney, J.A., Goellner, J.R., de Lellis, R.A., Heffess, C.S., Katoh, R., Observer variation of encapsulated follicular lesions of the thyroid gland (2002) Am J Surg Pathol, 26 (11), pp. 1508-14
dc.descriptionElsheikh, T.M., Asa, S.L., Chan, J.K., Delellis, R.A., Heffess, C.S., Livolsi, V.A., Interobserver and intraobserver variation among experts in the diagnosis of thyroid follicular lesions with borderline nuclear features of papillary carcinoma (2008) Am J Clin Pathol, 130 (5), pp. 736-44
dc.descriptionCrissman, J.D., Drozdowicz, S., Johnson, C., Kini, S.R., Fine needle aspiration diagnosis of hyperplastic and neoplastic follicular nodules of the thyroid (1991) Anal Quant Cytol Histol, 13 (5), pp. 321-8
dc.languagept
dc.publisher
dc.relationArquivos Brasileiros de Endocrinologia e Metabologia
dc.rightsaberto
dc.sourceScopus
dc.titleContribution Of Nuclear Texture Analysis For The Differential Diagnosis Of Follicular Lesions Of The Thyroid: Comparison To Immunohistochemical Markers [contribuição Da Análise De Textura Do Núcleo Celular Para O Diagnóstico Diferencial De Lesões Foliculares Da Tireoide: Comparação Com Marcadores Imunoistoquímicos]
dc.typeArtículos de revistas


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