Adaptive Response To Swimming Exercise: Antioxidant Systems And Lipid Peroxidation

dc.creatorCesquini M.
dc.creatorTorsoni M.A.
dc.creatorOgo S.H.
dc.date1999
dc.date2015-06-30T15:21:51Z
dc.date2015-11-26T15:27:55Z
dc.date2015-06-30T15:21:51Z
dc.date2015-11-26T15:27:55Z
dc.date.accessioned2018-03-28T22:36:36Z
dc.date.available2018-03-28T22:36:36Z
dc.identifier
dc.identifierJournal Of Anti-aging Medicine. , v. 2, n. 4, p. 357 - 364, 1999.
dc.identifier10945458
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0033367821&partnerID=40&md5=3dad2c640a548330d4c908883e2e8cc2
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/101159
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/101159
dc.identifier2-s2.0-0033367821
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1261464
dc.descriptionEnzymatic and nonenzymatic antioxidants play an essential role in protecting tissues from oxidative damage during exercise. The present study investigated the levels of glutathione and antioxidant enzyme systems in the blood of unexercised and exercised (one bout of exhaustive swimming and adapted to swimming endurance training) rats. The hemoglobin concentration, hematocrit, and extent of oxidative injury to red blood cell (RBC) membranes were examined in the above groups of rats. The concentration of reduced glutathione (GSH) in the blood of exercised rats was about 30% higher than in the resting controls (0.40 Å [±] 0.12 GSH/Hb tetramer). Glutathione peroxidase (1.83 Å 0.24 x 102 IU/g Hb), glutathione reductase (1.73 Å 0.44 IU/g Hb), and superoxide dismutase activities were significantly higher in both groups of exercised rats, whereas catalase activity (8.32 Å 1.04 x 104 IU/g Hb) was similar in the exercised and control animals. The hemoglobin concentration (11.8 g Hb/dL) and hematocrit (39.4%) increased with swimming exercise. Although lipid peroxidation is known to occur following physical exercise, the increased activity of the antioxidant enzymes and cell GSH levels in the present study were able to prevent lipid peroxidation of the RBC membrane. As a result, there was no significant variation in the plasma malondialdehyde levels among the three groups of rats. The redox capacity of the blood may have an important role in the organism in general since the redox status can be transferred across the RBC plasma membrane to other tissues. Exercise training is therefore beneficial to general health and protects cells against deleterious effects of reactive oxygen species produced during physical effort.
dc.description2
dc.description4
dc.description357
dc.description364
dc.descriptionMcArdle, W.D., Katch, V.L., (1985) Exercise Physiology, Energy, Nutrition and Human Performance, , Philadelphia: Lea and Febiger
dc.descriptionJi, L.L., Oxidative stress during exercise: Implication of antioxidant nutrients (1995) Free Radic Biol Med, 18, pp. 1079-1086
dc.descriptionMachlin, L.J., Bendich, A., Free radicals tissue damage: Protective role of antioxidant nutrients (1987) FASEB J, 1, pp. 441-445
dc.descriptionTravacio, M., Lleusy, S., Antioxidant enzymes and their modification under oxidative stress condition (1996) Free Radic Res Latin Am, 48, pp. 132-141
dc.descriptionSies, H., Oxidative stress (1985) Introductory Remarks in Oxidative Stress, pp. 1-8. , Sies H, ed. London: Academic Press
dc.descriptionZiegler, D.M., Role of reversible oxidation-reduction of enzyme thiol-disulfides in metabolic regulation (1985) Annu Rev Biochem, 54, pp. 305-329
dc.descriptionBellomo, G., Mirabelli, F., DiMonte, D., Formation and reduction of glutathione-protein mixed disulphides during oxidative stress (1987) Biochem Pharmacol, 33, pp. 1313-1320
dc.descriptionAlessio, H.M., Goldfarb, A.H., Lipid peroxidation and scavenger enzymes during exercise: Adaptative response to training (1988) J Appl Physiol, 64, pp. 1333-1336
dc.descriptionHalliwell, B., Gutteridge, J.M., (1989) Free Radicals in Biology and Medicine, , Oxford: Clarendon
dc.descriptionGohil, K., Rothfuss, L., Lang, J., Packer, L., Effect of exercise training on tissue vitamin E and ubiquinone content (1987) J Appl Physiol, 63, pp. 1638-1641
dc.descriptionQuintanilha, A.T., Oxidative effects of physical exercise (1988) Reactive Oxygen Species in Chemistry, Biology and Medicine, pp. 187-195. , Qintanilha AT, ed. New York: Plenum
dc.descriptionJi, L.L., Fu, R., Response of glutathione system and antioxidant enzymes to exhaustive exercise and hydroperoxide (1992) J Appl Physiol, 72, pp. 549-554
dc.descriptionClemens, M.R., Waller, H.D., Lipid peroxidation in erythrocytes (1987) Chem Phys Lipids, 45, pp. 257-268
dc.descriptionOhno, H.Y., Sato, K., Yamashita, R., The effect of brief physical exercise on free radical scavenging enzyme systems in human red blood cells (1986) Can J Physiol Pharmacol, 64, pp. 1263-1265
dc.descriptionJenkins, R.R., Newsholme, D., Catalase activity in electrically stimulated muscle (1980) Experientia, 36, pp. 843-844
dc.descriptionAntonini, E., Brunori, M., (1971) Hemoglobin and Myoglobin in Their Reactions with Ligands, , Amsterdam: North Holland
dc.descriptionWinterbourn, C., Oxidative reactions of hemoglobin (1990) Methods Enzymol, 186, pp. 265-272
dc.descriptionBeutler, E., (1975) Red Cell Metabolism: A Manual of Biochemical Methods, , London: Academic Press
dc.descriptionWinterbourn, C.C., Hawkins, R.E., Brian, M., Carrel, R.W., The estimation of red cell superoxide dismutase activity (1975) J Lab Clin Med, 85, pp. 337-341
dc.descriptionStocks, J., Dormandy, L., The autoxidation of human red blood cell lipids induced by hydrogen peroxide (1971) Br J Haematol, 20, pp. 95-98
dc.descriptionQuintanilha, A.T., Davies, K.J.A., Brooks, A.G., Packer, L., Free radicals and tissue damage produced by exercise (1982) Biochem Biophys Res Commun, 107, pp. 1198-1205
dc.descriptionJi, L.L., Dillon, D., Wu, E., Alteration of antioxidant enzymes with aging in rat skeletal muscle and liver (1990) Am J Physiol, 258, pp. R918-R923
dc.descriptionKanter, M.M., Hamlin, R.L., Unverferth, D.V., Davis, M.W., Merola, A.J., Effect of exercise training on antioxidation enzymes and cardiotoxicity of doxorubicin (1985) J Appl Physiol, 59, pp. 1298-1303
dc.descriptionLaughlin, M.H., Simpson, T., Sexton, W.L., Brown, O.R., Smith, J.K., Korthuis, R.J., Skeletal muscle oxidative capacity, antioxidant enzymes, and exercise training (1990) J Appl Physiol, 68, pp. 2337-2343
dc.descriptionPacker, L., Gohil, K., DeLumen, B., Terblanche, S.E., A comparative study on the effects of ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of the guinea pig (1986) Comp Biochem Physiol, 83 B, pp. 235-240
dc.descriptionReed, D.J., Basson, J.R., Beatty, P.W., Brodie, A.E., Ellis, W.W., Potter, D.W., High-performance liquid chromatogra-phy of nanomole levels of glutathione, glutathione disulfide and related thiols and disulfides (1980) Anal Biochem, 106, pp. 55-62
dc.descriptionAnderson, M.E., Bridges, R.J., Meister, A., Direct evidence for interorgan transport of glutathione and the non-filtration mechanism for glutathione utilization involving gamma glutamyl transpeptidase (1980) Biochem Biophys Res Commun, 96, pp. 848-853
dc.descriptionDeneke, S.M., Fanburg, B.L., Regulation of cellular glutathione (1989) Am J Physiol, 257, pp. L163-L173
dc.descriptionMeister, A., Glutathione metabolism and its selective modification (1988) J Biol Chem, 263, pp. 17205-17208
dc.descriptionGohil, K., Viguie, C., Stanley, W.C., Brooks, G.A., Parcker, L., Blood glutathione oxidation during human exercise (1988) J Appl Physiol, 64, pp. 115-119
dc.descriptionAnuradha, C.V., Increased erythrocyte lipid peroxidation and osmotic fragility in sports people (1995) Med Sci Res, 23, pp. 409-412
dc.descriptionLeeuwenburgh, C., Ji, L.L., Glutathione depletion in rested and exercised mice: Biochemical consequence and adaptation (1995) Arch Biochem Biophys, 316, pp. 941-949
dc.descriptionJi, L.L., Antioxidant enzyme response to exercise and aging (1993) Med Sci Sports Exerc, 25, pp. 225-231
dc.descriptionStorz, G., Tartaglia, L.A., Ames, B.N., Transcriptional regulator of oxidative stress-inducible genes: Direct activation by oxidation (1990) Science, 248, pp. 189-194
dc.descriptionJi, L.L., Stratman, F.W., Lardy, H.A., Enzymatic down regulation with exercise in rat skeletal muscle (1988) Arch Biochem Biophys, 263, pp. 137-149
dc.descriptionCohen, G., Hochstein, P., Glutathione peroxidase: The primary agent for the elimination of hydrogen peroxidase in erythrocytes (1963) Biochemistry, 2, pp. 1420-1428
dc.descriptionKurata, M., Suzuki, M., Agar, N.S., Antioxidant systems and erythrocyte life-span in mammals (1993) Comp Biochem Physiol, 106 B, pp. 477-1187
dc.descriptionQuiroga, G., Brown, B., Fat thermogenesis and exercise: Two examples of physiological oxidative stress (1992) Free Radic Biol Med, 13, pp. 325-340
dc.descriptionWhittlesey, M.J., Maresh, C.M., Armstrong, L.E., Plasma volume responses to consecutive anaerobic exercise tests (1996) Int J Sports Med, 17, pp. 268-271
dc.descriptionSenay, L.C., Rogers, G., Jooste, P., Changes in blood plasma during progressive treadmill and cycle exercise (1980) J Appl Physiol, 49, pp. 59-65
dc.descriptionReglinski, J., Hoey, S., Smith, W.E., Sturrock, R.D., Cellular response to oxidative stress at sufhydryl group receptor sites on the erythrocyte membrane (1988) J Biol Chem, 263, pp. 12360-12366
dc.languageen
dc.publisher
dc.relationJournal of Anti-Aging Medicine
dc.rightsfechado
dc.sourceScopus
dc.titleAdaptive Response To Swimming Exercise: Antioxidant Systems And Lipid Peroxidation
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución