Carta
Platelet Transfusion: From Empiricism To Scientific Evidence [transfusão De Plaquetas: Do Empirismo Ao Embasamento Científico]
Registro en:
Revista Brasileira De Hematologia E Hemoterapia. , v. 32, n. 4, p. 335 - 336, 2010.
15168484
2-s2.0-78649546042
Autor
Ferreira A.A.
Soares S.
de Castro V.
Moraes-Souza H.
Institución
Resumen
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion tests that may compromise transfusion safety is still observed at transfusion agencies in the fringes of the blood transfusion therapy system. Additionally, although high rates of platelet transfusion refractoriness and significant rates of alloimmunization have been demonstrated in the international literature, few Brazilian centers have been concerned with the study of platelet alloimmunization and even fewer centers have evaluated the efficacy of platelet concentrate transfusion. As more than one million Brazilians, including many repeat blood donors, are listed in the National Bone Marrow Donor Registry (Redome), why not grant transfusion therapy services access to the HLA typing of these blood and marrow donors after obtaining their consent? And why not make use of the Redome data to evaluate the HLA compatibility of donors for alloimmunized patients who are candidates for bone marrow transfusion and who have already been typed? These measures, together with the identification of ABO and HPA antigens, will permit a complete assessment of platelet immunology, will guarantee the transfusion safety of this blood component, and will put Brazil at the same level as the so-called developed countries in terms of transfusion medicine. 32 4 335 336 (2004) Aprova o Regulamento Técnico para os procedimentos de hemoterapia para coleta, processamento, testagem, armazenamento, transporte, utilização e controle de qualidade do sangue e seus componentes obtidos do sangue venoso, do cordão umbilical, da placenta e da medula óssea para uso humano, , Brasil. Resolução no 153, de 14 de junho de, Diário Oficial da União. Agência Nacional de Vigilância Martins, P.R.J., Martins, R.N., Pereira, G.A., Moraes-Souza, H., Frequência de anticorpos antieritrocitários irregulares em politransfundidos no Hemocentro Regional de Uberaba-MG, de 1997 a 2005 (2008) Rev. Bras. Hematol. Hemoter, 30 (4), pp. 272-276 Slichter, S.J., Davis, K., Enright, H., Braine, H., Gernsheimer, T., Kao, K., Factors affecting post-transfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients (2005) Blood, 105, pp. 4106-4114 Castro, V., Aloantígenos Plaquetários Humanos (2007) Hemoterapia: Fundamentos e Prática, pp. 193-200. , In: Bordin JO, Júnior DML, Covas DT, editors, 1a ed. São Paulo: Atheneu Fontão-Wendel, R., Silva, L.C., Saviolo, C.B., Primavera, B., Wendel, S., Incidence of transfusion-induced platelet-reactive antibodies evaluated by specific assays for the detection of human leucocyte antigen and human platelet antigen antibodies (2007) Vox Sanguinis, 93, pp. 241-249 Congresso Brasileiro de Hematologia e Hemoterapia HEMO 2009 (2009) Rev. Bras. Hematol. Hemoter, 31 (SUPL. 5) Hod, E., Schwartz, J., Platelet transfusion refractoriness (2008) Br J Haematol, 142, pp. 348-360