Biotransformation Of α-bromoacetophenones By The Marine Fungus Aspergillus Sydowii

dc.creatorRocha L.C.
dc.creatorFerreira H.V.
dc.creatorPimenta E.F.
dc.creatorBerlinck R.G.S.
dc.creatorRezende M.O.O.
dc.creatorLandgraf M.D.
dc.creatorSeleghim M.H.R.
dc.creatorSette L.D.
dc.creatorPorto A.L.M.
dc.date2010
dc.date2015-06-26T12:37:38Z
dc.date2015-11-26T15:27:37Z
dc.date2015-06-26T12:37:38Z
dc.date2015-11-26T15:27:37Z
dc.date.accessioned2018-03-28T22:36:18Z
dc.date.available2018-03-28T22:36:18Z
dc.identifier
dc.identifierMarine Biotechnology. , v. 12, n. 5, p. 552 - 557, 2010.
dc.identifier14362228
dc.identifier10.1007/s10126-009-9241-y
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-77957755661&partnerID=40&md5=57289003a101de3740bb155894df1540
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/91220
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/91220
dc.identifier2-s2.0-77957755661
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1261392
dc.descriptionThe biotransformation reactions of α-bromoacetophenone (1), p-bromo-α-bromoacetophenone (2), and p-nitro-α-bromoacetophenone (3) by whole cells of the marine fungus Aspergillus sydowii Ce19 have been investigated. Fungal cells that had been grown in artificial sea water medium containing a high concentration of chloride ions (1.20 M) catalysed the biotransformation of 1 to 2-bromo-1-phenylethanol 4 (56%), together with the α-chlorohydrin 7 (9%), 1-phenylethan-1,2-diol 9 (26%), acetophenone 10 (4%) and phenylethanol 11 (5%) identified by GC-MS analysis. In addition, it was observed that the enzymatic reaction was accompanied by the spontaneous debromination of 1 to yield α-chloroacetophenone 5 (9%) and α-hydroxyacetophenone 6 (18%) identified by GC-FID analysis. When 2 and 3 were employed as substrates, various biotransformation products were detected but the formation of halohydrins was not observed. It is concluded that marine fungus A. sydowii Ce19 presents potential for the biotransformations of bromoacetophenone derivatives. © 2009 Springer Science+Business Media, LLC.
dc.description12
dc.description5
dc.description552
dc.description557
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dc.languageen
dc.publisher
dc.relationMarine Biotechnology
dc.rightsfechado
dc.sourceScopus
dc.titleBiotransformation Of α-bromoacetophenones By The Marine Fungus Aspergillus Sydowii
dc.typeArtículos de revistas


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