Designer drug is a term used to describe psychoactive drugs of abuse which are usually synthesized by modifying the molecular structures of existing drugs of abuse. The term gained widespread popularity when MDMA (ecstasy) experienced a popularity boom in the mid 1980's. In Brazil, designer drugs seizures have increased in the last few years, and actually tablets with unknown psychoactive compounds began to be forwarded to the Forensic Laboratories. This work describes the analytical assays that were performed to identify the chlorophenylpiperazine, a psychoactive substance first time identified in seized tablets in Sao Paulo state.333725729http://www.unodc.org/unodc/en/data-and-analysis/WDR-2008.html, acessada em Fevereiro 2010Kovaleva, J., Devuyst, E., Paepe, P.D., Verstraete, A., (2008) Ther. Drug Monit., 30, p. 394http://www.emcdda.europa.eu/publications/drug-profiles/bzp, acessada em Fevereiro 2010Bossong, M.G., Dijk, J.P.V., Niesink, R.J.M., (2005) Addiction Biology, 10, p. 321Staack, R.F., Paul, L.D., Schmid, D., Roider, G., Rolf, B., (2007) J. Chromatogr. B, 855, p. 127Patel, B.N., Sharma, N., Sanyal, M., Shrivastav, P.S., (2008) J. Chromatogr. B, 871, p. 7. , http://e-legis.anvisa.gov.br/leisref/public/showAct.php?id= 33987&word=, acessada em Março 2009http://www.ncjrs.gov/pdffiles1/nij/183258.pdf, acessada em Março 2009Jeffrey, W., (2003) Em Clarke's Analysis of Drugs and Poisons in Pharmaceuticals, Body Fluids and Postmortem Material, p. 279. , Moffat, A. C.Osselton, M. D.Widdop, B., eds.Pharmaceutical Press: LondonTsumura, Y., Mitome, T., Kimoto, S., (2005) Forensic Sci. Int., 155, p. 158Poole, C.F., Em Ref., 9, p. 392Oguri, K., Sachiko, W., Shuichi, E., Hideyuki, Y., (1995) Japanese J. Toxicol. Environ. Health., 41, p. 274. , 44