Clinical Study Of The Efficacy And Tolerability Of Lansoprazole In The Management Of Duodenal Ulcer [estudo Clinico Sobre A Eficacia E A Tolerabilidade De Lansoprazol No Tratamento Da Ulcera Duodenal]

dc.creatorZaterka S.
dc.creatorDe Magalhaes A.F.N.
dc.creatorEisig J.N.
dc.creatorCosta Leite Carvalhaes A.A.
dc.creatorChinzon D.
dc.creatorNavarro Rodriguez T.
dc.date1998
dc.date2015-06-30T15:04:06Z
dc.date2015-11-26T15:11:57Z
dc.date2015-06-30T15:04:06Z
dc.date2015-11-26T15:11:57Z
dc.date.accessioned2018-03-28T22:22:05Z
dc.date.available2018-03-28T22:22:05Z
dc.identifier
dc.identifierRevista Brasileira De Medicina. , v. 55, n. 3, p. 156 - 160, 1998.
dc.identifier347264
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0031977326&partnerID=40&md5=9eadc85574059dc8d6845a2e86594670
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/100419
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/100419
dc.identifier2-s2.0-0031977326
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1258272
dc.descriptionThe present study aimed to evaluate the efficacy and tolerability of lansoprazole 30 mg once daily in healing duodenal ulcer in two Brazilian centers. Patients were evaluated on the basis of clinical and endoscopic criteria before treatment and two weeks after the beginning of treatment. The patients who were not healed (red or white scar: S1 or S2 according Sakitas's classification) were reevaluated 4 weeks after the beginning of treatment. Fifthy-eight patients completed the study. Endoscopic examination revealed that duodenal ulcer was healed (S1 or S2 according Sakitas's classification) 2 weeks after the beginning of treatment in 51 patients (87,9%). In the remaining seven patients (12,1%) the ulcer was healed at the end of treatment (4 weeks). Clinical symptoms (daytime epigastric pain, nocturnal epigastric pain, daytime heartburn, nocturnal heartburn, nausea, vomiting, post-prandial distention, anorexia, and dysphagia) were dramatically reduced two weeks after the beginning of treatment in terms of the number of patients presenting the symptom and the severity. The present study confirms the efficacy of lansoprazole in the treatment of duodenal ulcer. All patients who completed the study were healed. The adverse events reported were mild nature and were not considered related to the medication under study, not requiring discontinuation of treatment. With a marked efficacy lansoprazole is also safe.
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dc.languagees
dc.publisher
dc.relationRevista Brasileira de Medicina
dc.rightsfechado
dc.sourceScopus
dc.titleClinical Study Of The Efficacy And Tolerability Of Lansoprazole In The Management Of Duodenal Ulcer [estudo Clinico Sobre A Eficacia E A Tolerabilidade De Lansoprazol No Tratamento Da Ulcera Duodenal]
dc.typeArtículos de revistas


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