Phenotypic Characteristics Of Resistant Hypertension In The Brazilian Population [características Fenotípicas Da Hipertensão Arterial Resistente Na População Brasileira]

dc.creatorde Faria A.P.C.
dc.creatorSabbatini A.R.
dc.creatorCoca A.
dc.creatorMoreno H.
dc.date2013
dc.date2015-06-25T19:11:56Z
dc.date2015-11-26T15:09:19Z
dc.date2015-06-25T19:11:56Z
dc.date2015-11-26T15:09:19Z
dc.date.accessioned2018-03-28T22:19:31Z
dc.date.available2018-03-28T22:19:31Z
dc.identifier
dc.identifierArquivos Brasileiros De Cardiologia. , v. 100, n. 6, p. 579 - 582, 2013.
dc.identifier0066782X
dc.identifier10.5935/abc.20130100
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84880372143&partnerID=40&md5=a8efd16c2e75e13ba956c15a1d14185e
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/88678
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/88678
dc.identifier2-s2.0-84880372143
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1257792
dc.descriptionResistant hypertension (RH) is defined as blood pressure that remains above target in spite of the concurrent use of three or more classes of antihypertensive drugs at optimized doses (UCRH), with one of them being a diuretic. Moreover, patients whose blood pressure is controlled while using four or more antihypertensive medications are also considered controlled resistant hypertensive (CRH) subjects. Although this definition may be useful in terms of categorizing a larger group of resistant hypertensive individuals, as these two subgroups share high cardiovascular risk, some important clinical and pathophysiologic particularities need to be better evaluated, before considering resistant controlled and uncontrolled patients as part of the same group. We compared cardiovascular characteristics of these two subgroups with resistant hypertension. In spite of some similar features, the UCRH subgroup has cardiovascular phenotypes with worse prognosis, such as increased vascular stiffness and left ventricular hypertrophy, as well as more impaired endothelial function and lower nocturnal blood pressure dipping, among others. Considering these differences, the UCRH subgroup is associated with greater cardiovascular risk and may be considered as more resistant to antihypertensive treatment. In addition to the importance of better prevention and treatment of resistant hypertension by identifying early risk factors and optimizing drug therapy, some clinical implications must be considered when managing controlled and uncontrolled patients as similar to the resistant hypertension group.
dc.description100
dc.description6
dc.description579
dc.description582
dc.descriptionCalhoun, D.A., Jones, D., Textor, S., Goff, D.C., Murphy, T.P., Toto, R.D., Resistant hypertension: Diagnosis, evaluation, and treatment: A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research (2008) Circulation., 117 (25), pp. e510-e526
dc.descriptionCalhoun, D.A., Jones, D., Textor, S., Goff, D.C., Murphy, T.P., Toto, R.D., Resistant hypertension: Diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research (2008) Hypertension., 51 (6), pp. 1403-1419
dc.descriptionLloyd-Jones, D.M., Evans, J.C., Larson, M.G., O'Donnell, C.J., Roccella, E.J., Levy, D., Differential control of systolic and diastolic blood pressure: Factors associated with lack of blood pressure control in the community (2000) Hypertension., 36 (4), pp. 594-599
dc.descriptionCushman, W.C., Ford, C.E., Cutler, J.A., Margolis, K.L., Davis, B.R., Grimm, R.H., Success and predictors of blood pressure control in diverse North American settings: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) (2002) J Clin Hypertens (Greenwich)., 4 (6), pp. 393-404
dc.descriptionPimenta, E., Gaddam, K.K., Oparil, S., Aban, I., Husain, S., Dell'Italia, L.J., Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: Results from a randomized trial (2009) Hypertension., 54 (3), pp. 475-481
dc.descriptionCuspidi, C., Macca, G., Sampieri, L., Michev, I., Salerno, M., Fusi, V., High prevalence of cardiac and extracardiac target organ damage in refractory hypertension (2001) J Hypertens., 19 (11), pp. 2063-2070
dc.descriptionSalles, G.F., Cardoso, C.R., Pereira, V.S., Fiszman, R., Muxfeldt, E.S., Prognostic significance of a reduced glomerular filtration rate and interaction with microalbuminuria in resistant hypertension: A cohort study (2011) J Hypertens., 29 (10), pp. 2014-2023
dc.descriptionSalles, G.F., Fiszman, R., Cardoso, C.R., Muxfeldt, E.S., Relation of left ventricular hypertrophy with systemic inflammation and endothelial damage in resistant hypertension (2007) Hypertension., 50 (4), pp. 723-728
dc.descriptionSalles, G.F., Cardoso, C.R., Fiszman, R., Muxfeldt, E.S., Prognostic impact of baseline and serial changes in electrocardiographic left ventricular hypertrophy in resistant hypertension (2010) Am Heart J., 159 (5), pp. 833-840
dc.descriptionGus, M., Silva, D.N., Fernandes, J., Cunha, C.P., Sant'Anna, G.D., Epworth's sleepiness scale in outpatients with different values of arterial blood pressure (2002) Arq Bras Cardiol., 78 (1), pp. 17-24
dc.descriptionGus, M., Goncalves, S.C., Martinez, D., de Abreu Silva, E.O., Moreira, L.B., Fuchs, S.C., Risk for Obstructive Sleep Apnea by Berlin Questionnaire, but not daytime sleepiness, is associated with resistant hypertension: A case-control study (2008) Am J Hypertens., 21 (7), pp. 832-835
dc.descriptionPedrosa, R.P., Krieger, E.M., Lorenzi-Filho, G., Drager, L.F., Recent advances of the impact of obstructive sleep apnea on systemic hypertension (2011) Arq Bras Cardiol., 97 (2), pp. e40-e47
dc.descriptionPedrosa, R.P., Drager, L.F., Gonzaga, C.C., Sousa, M.G., de Paula, L.K., Amaro, A.C., Obstructive sleep apnea: The most common secondary cause of hypertension associated with resistant hypertension (2011) Hypertension., 58 (5), pp. 811-817
dc.descriptionWhaley-Connell, A., Johnson, M.S., Sowers, J.R., Aldosterone: Role in the cardiometabolic syndrome and resistant hypertension (2010) Prog Cardiovasc Dis., 52 (5), pp. 401-409
dc.descriptionSowers, J.R., Whaley-Connell, A., Epstein, M., Narrative review: The emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension (2009) Ann Intern Med., 150 (11), pp. 776-783
dc.descriptionDrager, L.F., Queiroz, E.L., Lopes, H.F., Genta, P.R., Krieger, E.M., Lorenzi-Filho, G., Obstructive sleep apnea is highly prevalent and correlates with impaired glycemic control in consecutive patients with the metabolic syndrome (2009) J Cardiometab Syndr., 4 (2), pp. 89-95
dc.descriptionMartins, L.C., Conceicao, F.L., Muxfeldt, E.S., Salles, G.F., Prevalence and associated factors of subclinical hypercortisolism in patients with resistant hypertension (2012) J Hypertens., 30 (5), pp. 967-973
dc.descriptionBoer-Martins, L., Figueiredo, V.N., Demacq, C., Martins, L.C., Consolin-Colombo, F., Figueiredo, M.J., Relationship of autonomic imbalance and circadian disruption with obesity and type 2 diabetes in resistant hypertensive patients (2011) Cardiovasc Diabetol., 10, p. 24
dc.descriptionUbaid-Girioli, S., Souza, A.L., Yugar-Toledo, J.C., Martins, L.C., Ferreira-Melo, S., Coelho, O.R., Aldosterone excess or escape: Treating resistant hypertension (2009) J Clin Hypertens (Greenwich)., 11 (5), pp. 245-252
dc.descriptionBoer-Martins, L., Figueiredo, V.N., Demacq, C., Martins, L.C., Faria, A.P., Moraes, C.D., Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes (2012) Arq Bras Cardiol., 99 (1), pp. 642-648
dc.descriptionde Souza, F., Muxfeldt, E., Fiszman, R., Salles, G., Efficacy of spironolactone therapy in patients with true resistant hypertension (2010) Hypertension., 55 (1), pp. 147-152
dc.descriptionAcelajado, M.C., Pisoni, R., Dudenbostel, T., Dell'Italia, L.J., Cartmill, F., Zhang, B., Refractory hypertension: Definition, prevalence, and patient characteristics (2012) J Clin Hypertens (Greenwich)., 14 (1), pp. 7-12
dc.descriptionMoreno Jr., H., Coca, A., Resistant and refractory hypertension: Reflections on pathophysiology and terminology (2012) Blood pressure., 21 (4), pp. 209-210
dc.descriptionMartins, L.C., Figueiredo, V.N., Quinaglia, T., Boer-Martins, L., Yugar-Toledo, J.C., Martin, J.F., Characteristics of resistant hypertension: Ageing, body mass index, hyperaldosteronism, cardiac hypertrophy and vascular stiffness (2011) J Hum Hypertens., 25 (9), pp. 532-538
dc.descriptionFigueiredo, V.N., Yugar-Toledo, J.C., Martins, L.C., Martins, L.B., de Faria, A.P., de Haro Moraes, C., Vascular stiffness and endothelial dysfunction: Correlations at different levels of blood pressure (2012) Blood Press, 21 (1), pp. 31-38
dc.descriptionQuinaglia, T., Martins, L.C., Figueiredo, V.N., Santos, R.C., Yugar-Toledo, J.C., Martin, J.F., Non-dipping pattern relates to endothelial dysfunction in patients with uncontrolled resistant hypertension (2011) J Hum Hypertens., 25 (11), pp. 656-664
dc.descriptionde Haro Moraes, C., Figueiredo, V.N., de Faria, A.P., Barbaro, N.R., Sabbatini, A.R., Quinaglia, T., High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension (2012) J Hum Hypertens, , Jul 19[epub ahead of print]
dc.languageen
dc.languagept
dc.publisher
dc.relationArquivos Brasileiros de Cardiologia
dc.rightsaberto
dc.sourceScopus
dc.titlePhenotypic Characteristics Of Resistant Hypertension In The Brazilian Population [características Fenotípicas Da Hipertensão Arterial Resistente Na População Brasileira]
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución