dc.creator | Santiago Bastos J.C. | |
dc.creator | Konecny Kohn L. | |
dc.creator | Fantinatti-Garboggini F. | |
dc.creator | Aiello Padilla M. | |
dc.creator | Furtado Flores E. | |
dc.creator | da Silva B.P. | |
dc.creator | de Menezes C.B.A. | |
dc.creator | Weis Arns C. | |
dc.date | 2013 | |
dc.date | 2015-06-25T19:10:41Z | |
dc.date | 2015-11-26T15:08:17Z | |
dc.date | 2015-06-25T19:10:41Z | |
dc.date | 2015-11-26T15:08:17Z | |
dc.date.accessioned | 2018-03-28T22:18:41Z | |
dc.date.available | 2018-03-28T22:18:41Z | |
dc.identifier | | |
dc.identifier | Viruses. , v. 5, n. 5, p. 1219 - 1230, 2013. | |
dc.identifier | 19994915 | |
dc.identifier | 10.3390/v5051219 | |
dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-84876925732&partnerID=40&md5=bf2aa07132e9ba7316e27c4350dbd3d8 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/88547 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/88547 | |
dc.identifier | 2-s2.0-84876925732 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1257633 | |
dc.description | The Hepatitis C virus causes chronic infections in humans, which can develop to liver cirrhosis and hepatocellular carcinoma. The Bovine viral diarrhea virus is used as a surrogate model for antiviral assays for the HCV. From marine invertebrates and microorganisms isolated from them, extracts were prepared for assessment of their possible antiviral activity. Of the 128 tested, 2 were considered active and 1 was considered promising. The best result was obtained from the extracts produced from the Bacillus sp. isolated from the sponge Petromica citrina. The extracts 555 (500 μg/mL, SI>18) and 584 (150 μg/mL, SI 27) showed a percentage of protection of 98% against BVDV, and the extract 616, 90% of protection. All of them showed activity during the viral adsorption. Thus, various substances are active on these studied organisms and may lead to the development of drugs which ensure an alternative therapy for the treatment of hepatitis C. © 2013 by the authors; licensee MDPI, Basel, Switzerland. | |
dc.description | 5 | |
dc.description | 5 | |
dc.description | 1219 | |
dc.description | 1230 | |
dc.description | Yasuhara-Bell, J., Yang, Y., Barlow, R., Trapido-Rosental, H., Lu, Y., In vitro evaluation of marine microorganism extracts for antiviral activity (2010) Virol. J., 7, p. 182 | |
dc.description | Ravikumar, Y.S., Upasana, R., Nandhitha, M., Perween, A., Naika, H.R., Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as a potent natural source (2011) Virus Res., 158, pp. 89-97 | |
dc.description | Li, H., Stoddard, M.B., Wang, S., Blair, L.M., Giorgi, E.E., Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome sequencing (2012) PLoS Pathog., 8, pp. e1002880 | |
dc.description | Suzuki, T., Ishii, K., Aizaki, H., Wakita, T., Hepatitis C viral life cycle (2007) Adv. Drug Del. Rev., 59, pp. 1200-1212 | |
dc.description | Barnes, E., Folgori, A., Capone, S., Swadling, L., Aston, S., Kurioka, A., Meyer, J., Klenerman, P., Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man (2012) SciTransl Med., 4, pp. 115ra1. , doi:10.1126/scitranslmed.3003155 | |
dc.description | Sako, K., Aoyama, H., Sato, S., Hashimoto, Y., Baba, M., γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity (2008) Bioorg. Med. Chem., 16, pp. 3780-3790 | |
dc.description | Martinot-Peignoux, M., Boyer, N., Pouteau, M., Castelnau, C., Giuily, N., Duchatelle, V., Aupérin, A., Erlinger, S., Predictors of sustained response to alpha interferon therapy in chronic hepatitis C (1998) J. Hepatol., 29, pp. 214-223 | |
dc.description | Lemon, S.M., McKeating, J.A., Pietschmann, T., Frick, D.N., Glenn, J.S., Tellinghuisen, T.L., Symons, J., Furman, P.A., Development of novel therapies for hepatitis C (2010) Antiviral Res., 86, pp. 79-92 | |
dc.description | Duverlie, G., Wychowski, C., Cell culture systems for the hepatitis C virus (2007) J. Gastroenterol., 13, pp. 2442-2445 | |
dc.description | Finkielsztein, L.M., Moltrasio, G.Y., Caputto, M.E., Castro, E.F., Cavallaro, L.V., Moglioni, A.G., What is known about the antiviral agents active against bovine viral diarrhea virus (BVDV)? (2010) Curr. Med. Chem., 17, pp. 2933-2955 | |
dc.description | Buckwold, V.E., Beer, B.E., Donis, R.O., Bovine viral diarrhea virus as a surrogate model of hepatitis C virus for the evaluation of antiviral agents (2003) Antiviral Res., 60, pp. 1-15 | |
dc.description | Zitzmann, N., Mehta, A.S., Carrouee, S., Butters, T.D., Platt, F.M., McCauley, J., Blumberg, B.S., Block, T.M., Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a Pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents (1999) Proc. Natl. Acad. Sci., 96, pp. 11878-11882 | |
dc.description | Baginski, S.G., Pevear, D.C., Seipel, M., Sun, S.C., Benetatos, C.A., Chunduru, S.K., Rice, C.M., Collett, M.S., Mechanism of action of a pestivirus antiviral compound (2000) Proc. Natl. Acad. Sci., 97, pp. 7981-7986 | |
dc.description | Buckwold, V.E., Wei, J., Wenzel-Mathers, M., Russell, J., Synergistic in vitro interactions between alpha interferon and ribavirin against bovine viral diarrhea virus and yellow fever virus as surrogate models of hepatitis C virus replication (2003) Antimicrobial. Agents Chemother., 47, pp. 2293-2298 | |
dc.description | Yanagida, K., Baba, C., Baba, M., Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: Synergistic effect of combination with interferon-α (2004) Antiviral Res., 64, pp. 195-201 | |
dc.description | Mosmann, T., Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays (1983) J. Immun. Meth., 65, pp. 55-63 | |
dc.description | Scudiero, D.A., Shoemaker, R.H., Paull, K.D., Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines (1988) Cancer Res., 48, pp. 4827-4833 | |
dc.description | Reed, L.J., Münch, H.A., A simple method of estimating fifty percent endpoints (1938) Am. J. Hyg., 27, pp. 493-497 | |
dc.description | Takeuchi, H., Baba, M., Shigeta, S., An application of tetrazolium (MTT) colorimetric assay for the screening of anti-herpes simplex virus compounds (1991) J. Virol. Methods., 33, pp. 61-71 | |
dc.description | Koseki, I., Simoni, I.C., Nakamura, I.T., Noronha, A.B., Costa, S.S., Antiviral activity of plant extracts against aphtovirus, pseudorabiesvírus and pestivirus in cell cultures (1990) Microbios. Letters., 44, pp. 19-30 | |
dc.description | Pospiech, A., Neumann, B., A versatile quick-prep of genomic DNA from Gram-positive bacteria (1995) Trends Genetics, 11, pp. 217-218 | |
dc.description | Lane, D.J., Pace, B., Olsen, G.J., Stahl, D.A., Sogin, M.L., Pace, N.R., Rapid determination of 16S ribosomal RNA sequences for phylogenetic analysis (1985) Proc. Nat. Acad. Sci., 82, pp. 6955-6959 | |
dc.description | Menezes, C.B.A., Bonugli-Santos, R.C., Miqueletto, P.B., Passarini, M.R.Z., Silva, C.H.D., Justo, M.R., Rebeca, R., Sette, L.D., Microbial diversity associated with algae, ascidians and sponges from the north coast of São Paulo state, Brazil (2010) Microbiol. Res., 165, pp. 466-482 | |
dc.description | Costa-Lotufo, L.V., Wilke, D.V., Jimenez, P.C., Epifanio, R.A., Organismos marinhos como fonte de novos fármacos: Histórico & perspectivas (2009) Quim. Nova., 32, pp. 703-716 | |
dc.description | Laport, M.S., Santos, O.C., Muricy, G., Marine sponges: Potential sources of new antimicrobial drugs (2009) Curr. Pharm. Biotechnol., 10, pp. 86-105 | |
dc.description | Marinho, P.R., Muricy, G.R.S., Silva, M.F.L., de Marval, M.G., Laport, M.S., Antibiotic-resistant bacteria inhibited by extracts and fractions from Brazilian marine sponges (2010) Brazilian J. Pharmac., 20, pp. 267-275 | |
dc.description | Donadio, S., Monciardini, P., Sosio, M., Polyketide synthases and nonribosomal peptide synthetases: The emerging view from bacterial genomics (2007) Nat. Prod. Rep., 24, pp. 1073-1109 | |
dc.description | Mikhaǐlova, N.A., Nagieva, F.G., Grin'ko, O.M., Zverev, V.V., Experimental study of antiviral activity of spore-forming bacterium Bacillus pumilus "Pashkov" (2010) Mikrobiol. Epidemiol. Immunobiol., 2, pp. 69-74 | |
dc.description | Gribencha, S.V., Potselueva, L.A., Barinskiǐ, I.F., Deev, S.M., Balandin, T.G., Leshchinskaia, I.B., Antiviral activity of Bacillus intermedius RNAase in guinea-pigs and rabbits infected with outdoor rabies virus (2006) Vopr. Virusol., 51, pp. 41-43 | |
dc.description | Gribencha, S.V., Potselueva, L.A., Barinskiǐ, I.F., Balandin, T.G., Deev, S.M., Leshchinskaia, I.B., The antiviral activity of RNAse Bacillus intermedius in experiments with mice preinfected with street rabies virus (2004) Vopr. Virusol., 49, pp. 38-41 | |
dc.description | Zhou, W.W., Niu, T.G., Purification and some properties of an extracellular ribonuclease with antiviral activity against tobacco mosaic virus from Bacillus cereus (2009) Biotechnol. Lett., 31, pp. 101-105 | |
dc.description | Boya, C.A., Herrera, L., Guzman, H.M., Gutierrez, M., Antiplasmodial activity of bacilosarcinA isolated from the octocoral-associated bacterium Bacillus sp. collected in Panama (2012) J. Pharm. Bioallied. Sci., 4, pp. 66-69 | |
dc.description | El-Sersy, N.A., Abdelwahab, A.E., Abouelkhiir, S.S., Antibacterial and anticancer activity of ε-poly-L-lysine (ε-PL) produced by a marine Bacillus subtilis sp (2012) J. Basic Microbiol., 52, pp. 513-522 | |
dc.description | Craczyc, K., Trojanowska, K., Mueller, A., Antifungal activity of Bacillus coagulans against Fusarium sp (2002) Acta Microbiol. Pol., 51, pp. 275-283 | |
dc.description | Sohn, M.J., Zheng, C.J., Kim, W.G., Macrolactin S, a new antibacterial agent with FabG-inhibitory activity from Bacillus sp. AT28 (2008) J. Antibiot., 61, pp. 687-691 | |
dc.description | Moshafi, M.H., Forootanfar, H., Ameri, A., Antimicrobial activity of Bacillus sp. strain FAS1 isolated from soil. Pak (2011) J. Pharm. Sci., 24, pp. 269-275 | |
dc.language | en | |
dc.publisher | | |
dc.relation | Viruses | |
dc.rights | aberto | |
dc.source | Scopus | |
dc.title | Antiviral Activity Of Bacillus Sp. Isolated From The Marine Sponge Petromica Citrina Against Bovine Viral Diarrhea Virus, A Surrogate Model Of The Hepatitis C Virus | |
dc.type | Artículos de revistas | |