Tribulus Terrestris Versus Placebo In The Treatment Of Erectile Dysfunction: A Prospective, Randomized, Double Blind Study [tribulus Terrestris Versus Placebo En El Tratamiento De La Disfunción Eréctil: Un Estudio Aleatorizado, Prospectivo Y Doble Ciego]

dc.creatorSantos Jr. C.A.
dc.creatorReis L.O.
dc.creatorDestro-Saade R.
dc.creatorLuiza-Reis A.
dc.creatorFregonesi A.
dc.date2014
dc.date2015-06-25T18:02:48Z
dc.date2015-11-26T15:04:59Z
dc.date2015-06-25T18:02:48Z
dc.date2015-11-26T15:04:59Z
dc.date.accessioned2018-03-28T22:15:49Z
dc.date.available2018-03-28T22:15:49Z
dc.identifier
dc.identifierActas Urologicas Espanolas. Elsevier Ltd, v. 38, n. 4, p. 244 - 248, 2014.
dc.identifier2104806
dc.identifier10.1016/j.acuro.2013.09.014
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84899914873&partnerID=40&md5=4d5e95f3d97c660f7676de477657f8a5
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/87909
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/87909
dc.identifier2-s2.0-84899914873
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1256977
dc.descriptionObjectives To evaluate the possible effects of Tribulus terrestris herbal medicine in the erectile dysfunction treatment and to quantify its potential impact on serum testosterone levels. Design and methods Prospective, randomized, double-blind and placebo-controlled study including thirty healthy men selected from 100 patients who presented themselves spontaneously complaining of erectile dysfunction, ≥ 40 years of age, nonsmokers, not undergoing treatment for prostate cancer or erectile dysfunction, no dyslipidemia, no phosphodiesterase inhibitor use, no hormonal manipulation and, if present hypertension and/or diabetes mellitus should be controlled. International Index of Erectile Function (IIEF-5) and serum testosterone were obtained before randomization and after 30 days of study. Patients were randomized into two groups of fifteen subjects each. The study group received 800 mg of Tribulus terrestris, divided into two doses per day for thirty days and the control group received placebo administered in the same way. Results The groups were statistically equivalent in all aspects evaluated. The mean (SD) age was 60 (9.4) and 62.9 (7.9), P =.36 for intervention and placebo groups, respectively. Before treatment, the intervention group showed mean IIEF-5 of 13.2 (5-21) and mean total testosterone 417.1 ng/dl (270.7-548.4 ng/dl); the placebo group showed mean IIEF-5 of 11.6 (6-21) and mean total testosterone 442.7 ng/dl (301-609.1 ng/dl). After treatment, the intervention group showed mean IIEF-5 of 15.3 (5-21) and mean total testosterone 409.3 ng/dl (216.9-760.8 ng/dl); the placebo group showed mean IIEF-5 of 13.7 (6-21) and mean total testosterone 466.3 ng/dl (264.3-934.3 ng/dl). The time factor caused statistically significant changes in both groups for IIEF-5 only (P =.0004), however, there was no difference between the two groups (P =.7914). Conclusions At the dose and interval studied, Tribulus terrestris was not more effective than placebo on improving symptoms of erectile dysfunction or serum total testosterone. © 2013 AEU. Published by Elsevier Espana, S.L. All rights reserved.
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dc.description248
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dc.languagees
dc.publisherElsevier Ltd
dc.relationActas Urologicas Espanolas
dc.rightsfechado
dc.sourceScopus
dc.titleTribulus Terrestris Versus Placebo In The Treatment Of Erectile Dysfunction: A Prospective, Randomized, Double Blind Study [tribulus Terrestris Versus Placebo En El Tratamiento De La Disfunción Eréctil: Un Estudio Aleatorizado, Prospectivo Y Doble Ciego]
dc.typeArtículos de revistas


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