Artículos de revistas
Reference Values For High-density Lipoprotein Particle Size And Volume By Dynamic Light Scattering In A Brazilian Population Sample And Their Relationships With Metabolic Parameters
Registro en:
Clinica Chimica Acta. Elsevier, v. 442, n. , p. 63 - 72, 2015.
98981
10.1016/j.cca.2015.01.006
2-s2.0-84921709088
Autor
Alexandre F.
Zago V.H.S.
Panzoldo N.B.
Parra E.S.
Scherrer D.Z.
Vendrame F.
Nunes V.S.
Gomes E.I.L.
Marcato P.D.
Nakandakare E.R.
Quintao E.C.R.
de Faria E.C.
Institución
Resumen
Background: Current data indicate that the size of high-density lipoprotein (HDL) may be considered an important marker for cardiovascular disease risk. We established reference values of mean HDL size and volume in an asymptomatic representative Brazilian population sample (n= 590) and their associations with metabolic parameters by gender. Methods: Size and volume were determined in HDL isolated from plasma by polyethyleneglycol precipitation of apoB-containing lipoproteins and measured using the dynamic light scattering (DLS) technique. Results: Although the gender and age distributions agreed with other studies, the mean HDL size reference value was slightly lower than in some other populations. Both HDL size and volume were influenced by gender and varied according to age. HDL size was associated with age and HDL-C (total population); non- white ethnicity and CETP inversely (females); HDL-C and PLTP mass (males). On the other hand, HDL volume was determined only by HDL-C (total population and in both genders) and by PLTP mass (males). Conclusions: The reference values for mean HDL size and volume using the DLS technique were established in an asymptomatic and representative Brazilian population sample, as well as their related metabolic factors. HDL-C was a major determinant of HDL size and volume, which were differently modulated in females and in males. 442
63 72 Assmann, G., Gotto, A.M., HDL cholesterol and protective factors in atherosclerosis (2004) Circulation, 109. , III8-III14 Koro, C.E., Bowlin, S.J., Stump, T.E., Sprecher, D.L., Tierney, W.M., The independent correlation between high-density lipoprotein cholesterol and subsequent major adverse coronary events (2006) Am Heart J, 151. , 755.e1-755.e6 Linsel-Nitschke, P., Tall, A.R., HDL as a target in the treatment of atherosclerotic cardiovascular disease (2005) Nat Rev Drug Discov, 4, pp. 193-205 Camont, L., Chapman, M.J., Kontush, A., Biological activities of HDL subpopulations and their relevance to cardiovascular disease (2011) Trends Mol Med, 17, pp. 594-603 Rosenson, R.S., Brewer, H.B., Chapman, M.J., HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events (2011) Clin Chem, 57, pp. 392-410 Mackey, R.H., Greenland, P., Goff, D.C., Lloyd-Jones, D., Sibley, C.T., Mora, S., High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (Multi-Ethnic Study of Atherosclerosis) (2012) J Am Coll Cardiol, 60, pp. 508-516 Sviridov, D., Mukhamedova, N., Remaley, A.T., Chin-Dusting, J., Nestel, P., Antiatherogenic functionality of high density lipoprotein: how much versus how good (2008) J Atheroscler Thromb, 15, pp. 52-62 Watanabe, H., Soderlund, S., Soro-Paavonen, A., Decreased high-density lipoprotein (HDL) particle size, prebeta-, and large HDL subspecies concentration in Finnish low-HDL families: relationship with intima-media thickness (2006) Arterioscler Thromb Vasc Biol, 26, pp. 897-902 Arsenault, B.J., Lemieux, I., Despres, J.P., Comparison between gradient gel electrophoresis and nuclear magnetic resonance spectroscopy in estimating coronary heart disease risk associated with LDL and HDL particle size (2010) Clin Chem, 56, pp. 789-798 Musunuru, K., Orho-Melander, M., Caulfield, M.P., Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk (2009) Arterioscler Thromb Vasc Biol, 29, pp. 1975-1980 Mora, S., Otvos, J.D., Rifai, N., Rosenson, R.S., Buring, J.E., Ridker, P.M., Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women (2009) Circulation, 119, pp. 931-939 Packard, C.J., Shepherd, J., Joerns, S., Gotto, A.M., Taunton, O.D., Very low density and low density lipoprotein subfractions in type III and type IV hyperlipoproteinemia. Chemical and physical properties (1979) Biochim Biophys Acta, 572, pp. 269-282 Lima, E.S., Maranhao, R.C., Rapid, simple laser-light-scattering method for HDL particle sizing in whole plasma (2004) Clin Chem, 50, pp. 1086-1088 Sakurai, T., Trirongjitmoah, S., Nishibata, Y., Measurement of lipoprotein particle sizes using dynamic light scattering (2010) Ann Clin Biochem, 47, pp. 476-481 O'Neal, D., Harrip, P., Dragicevic, G., Rae, D., Best, J.D., A comparison of LDL size determination using gradient gel electrophoresis and light-scattering methods (1998) J Lipid Res, 39, pp. 2086-2090 Razavi, A.E., Ani, M., Pourfarzam, M., Naderi, G.A., Associations between high density lipoprotein mean particle size and serum paraoxonase-1 activity (2012) J Res Med Sci, 17, pp. 1020-1026 Kivatinitz, S.C., Pelsman, M.A., Alonso, A.C., Bagatolli, L., Quiroga, S., High-density lipoprotein aggregated by oxidation induces degeneration of neuronal cells (1997) J Neurochem, 69, pp. 2102-2114 Friedewald, W.T., Levy, R.I., Fredrickson, D.S., Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge (1972) Clin Chem, 18, pp. 499-502 Jauhiainen, M., Dolphin, P.J., Human plasma lecithin-cholesterol acyltransferase. An elucidation of the catalytic mechanism (1986) J Biol Chem, 261, pp. 7032-7043 Dobiasova, M., Stribrna, J., Pritchard, P.H., Frohlich, J.J., Cholesterol esterification rate in plasma depleted of very low and low density lipoproteins is controlled by the proportion of HDL2 and HDL3 subclasses: study in hypertensive and normal middle-aged and septuagenarian men (1992) J Lipid Res, 33, pp. 1411-1418 Ehnholm, C., Kuusi, T., Preparation, characterization, and measurement of hepatic lipase (1986) Methods Enzymol, 129, pp. 716-738 Lagrost, L., Determination of the mass concentration and the activity of the plasma cholesteryl ester transfer protein (CETP) (1998) Methods Mol Biol, 110, pp. 231-241 Jauhiainen, M., Ehnholm, C., Determination of human plasma phospholipid transfer protein mass and activity (2005) Methods, 36, pp. 97-101 Dias, V.C., Parsons, H.G., Boyd, N.D., Keane, P., Dual-precipitation method evaluated for determination of high-density lipoprotein (HDL), HDL2, and HDL3 cholesterol concentrations (1988) Clin Chem, 34, pp. 2322-2327 Chapman, M.J., Goldstein, S., Lagrange, D., Laplaud, P.M., A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum (1981) J Lipid Res, 22, pp. 339-358 Mallol, R., Rodriguez, M.A., Heras, M., Particle size measurement of lipoprotein fractions using diffusion-ordered NMR spectroscopy (2012) Anal Bioanal Chem, 402, pp. 2407-2415 Vaccarino, V., Badimon, L., Corti, R., Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology (2011) Cardiovasc Res, 90, pp. 9-17 Burt, V.L., Whelton, P., Roccella, E.J., Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991 (1995) Hypertension, 25, pp. 305-313 Ross, R.L., Serock, M.R., Khalil, R.A., Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease (2008) Curr Cardiol Rev, 4, pp. 309-322 Freedman, D.S., Otvos, J.D., Jeyarajah, E.J., Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study (2004) Clin Chem, 50, pp. 1189-1200 El Harchaoui, K., Arsenault, B.J., Franssen, R., High-density lipoprotein particle size and concentration and coronary risk (2009) Ann Intern Med, 150, pp. 84-93 Mantyselka, P., Kautiainen, H., Saltevo, J., Weight change and lipoprotein particle concentration and particle size: a cohort study with 6.5-year follow-up (2012) Atherosclerosis, 223, pp. 239-243 Giribela, A.H., Melo, N.R., Latrilha, M.C., Baracat, E.C., Maranhao, R.C., HDL concentration, lipid transfer to HDL, and HDL size in normolipidemic nonobese menopausal women (2009) Int J Gynaecol Obstet, 104, pp. 117-120 da Silva, I.T., Timm Ade, S., Damasceno, N.R., Influence of obesity and cardiometabolic makers on lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in adolescents: the healthy young cross-sectional study (2013) Lipids Health Dis, 12, p. 19 Johnson, J.L., Slentz, C.A., Duscha, B.D., Gender and racial differences in lipoprotein subclass distributions: the STRRIDE study (2004) Atherosclerosis, 176, pp. 371-377 Natori, S., Lai, S., Finn, J.P., Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity (2006) AJr. Am J Roentgenol, 186, pp. S357-S365 Williams, P.T., Vranizan, K.M., Austin, M.A., Krauss, R.M., Associations of age, adiposity, alcohol intake, menstrual status, and estrogen therapy with high-density lipoprotein subclasses (1993) Arterioscler Thromb, 13, pp. 1654-1661 Freedman, D.S., Bowman, B.A., Srinivasan, S.R., Berenson, G.S., Otvos, J.D., Distribution and correlates of high-density lipoprotein subclasses among children and adolescents (2001) Metabolism, 50, pp. 370-376 Berg, G.A., Siseles, N., Gonzalez, A.I., Ortiz, O.C., Tempone, A., Wikinski, R.W., Higher values of hepatic lipase activity in postmenopause: relationship with atherogenic intermediate density and low density lipoproteins (2001) Menopause, 8, pp. 51-57 Matthews, K.A., Kuller, L.H., Sutton-Tyrrell, K., Chang, Y.F., Changes in cardiovascular risk factors during the perimenopause and postmenopause and carotid artery atherosclerosis in healthy women (2001) Stroke, 32, pp. 1104-1111 Greenfield, M.S., Kraemer, F., Tobey, T., Reaven, G., Effect of age on plasma triglyceride concentrations in man (1980) Metabolism, 29, pp. 1095-1099 Cullen, P., Schulte, H., Assmann, G., The Munster Heart Study (PROCAM): total mortality in middle-aged men is increased at low total and LDL cholesterol concentrations in smokers but not in nonsmokers (1997) Circulation, 96, pp. 2128-2136 Abeywardena, M.Y., Dietary fats, carbohydrates and vascular disease: Sri Lankan perspectives (2003) Atherosclerosis, 171, pp. 157-161 Vergeer, M., Boekholdt, S.M., Sandhu, M.S., Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility (2010) Circulation, 122, pp. 470-477 Toth, P.P., Thakker, K.M., Jiang, P., Padley, R.J., Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy (2012) Vasc Health Risk Manag, 8, pp. 39-44 Santos, P.C., Pereira, A.C., Cancado, R.D., HFE gene mutations in patients with primary iron overload: is there a significant improvement in molecular diagnosis yield with HFE sequencing? (2010) Blood Cells Mol Dis, 45, pp. 302-307 Olinto, M.T., Willett, W.C., Gigante, D.P., Victora, C.G., Sociodemographic and lifestyle characteristics in relation to dietary patterns among young Brazilian adults (2011) Public Health Nutr, 14, pp. 150-159 (2011) Características Étnico-Raciais da População, , [Rio de Janeiro], (IBGE) IBdGeE Silva, R.A., Huang, R., Morris, J., Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes (2008) Proc Natl Acad Sci U S A, 105, pp. 12176-12181 Huang, R., Silva, R.A., Jerome, W.G., Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma (2011) Nat Struct Mol Biol, 18, pp. 416-422 Chapman, M.J., Le Goff, W., Guerin, M., Kontush, A., Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors (2010) Eur Heart J, 31, pp. 149-164 Stahlman, M., Fagerberg, B., Adiels, M., Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles (1831) Biochim Biophys Acta, 2013, pp. 1609-1617 Kunitake, S.T., Mendel, C.M., Hennessy, L.K., Interconversion between apolipoprotein A-I-containing lipoproteins of pre-beta and alpha electrophoretic mobilities (1992) J Lipid Res, 33, pp. 1807-1816 Lagrost, L., Athias, A., Herbeth, B., Opposite effects of cholesteryl ester transfer protein and phospholipid transfer protein on the size distribution of plasma high density lipoproteins. Physiological relevance in alcoholic patients (1996) J Biol Chem, 271, pp. 19058-19065 Villard, E.F., El Khoury, P., Duchene, E., Elevated CETP activity improves plasma cholesterol efflux capacity from human macrophages in women (2012) Arterioscler Thromb Vasc Biol, 32, pp. 2341-2349 Cheung, M.C., Wolfbauer, G., Deguchi, H., Fernandez, J.A., Griffin, J.H., Albers, J.J., Human plasma phospholipid transfer protein specific activity is correlated with HDL size: implications for lipoprotein physiology (2009) Biochim Biophys Acta, 1791, pp. 206-211