| dc.creator | Saad S.T.O. | |
| dc.date | 2010 | |
| dc.date | 2015-06-26T12:37:49Z | |
| dc.date | 2015-11-26T14:57:53Z | |
| dc.date | 2015-06-26T12:37:49Z | |
| dc.date | 2015-11-26T14:57:53Z | |
| dc.date.accessioned | 2018-03-28T22:09:39Z | |
| dc.date.available | 2018-03-28T22:09:39Z | |
| dc.identifier | | |
| dc.identifier | Revista Brasileira De Hematologia E Hemoterapia. , v. 32, n. SUPPL. 2, p. 99 - 104, 2010. | |
| dc.identifier | 15168484 | |
| dc.identifier | 10.1590/S1516-84842010005000067 | |
| dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-78649619086&partnerID=40&md5=4e43f743993ba0390bc6f649930b4263 | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/91247 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/91247 | |
| dc.identifier | 2-s2.0-78649619086 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1255744 | |
| dc.description | The genetic causes of iron deficiency, real or functional, occur due to defects in many proteins involved in the absorption and metabolism of iron. In this chapter we briefly describe the genetic causes of iron deficiency in the synthesis of hemoglobin, resulting in hypochromic or microcytic anemia. These alterations are rare with few descriptions in the literature. In some cases, functional iron is not available for erythroblasts to synthesis hemoglobin, or erythroblasts may be incapable of capturing iron from the circulation although iron is accumulated in tissues and mitochondrias. Many discoveries have been made over the last few years, mainly resulting from the description of human or animal models, which have elucidated the implications of the components in iron metabolism in hereditary iron deficiency involving all processes from intestinal absorption to the final inclusion into heme. | |
| dc.description | 32 | |
| dc.description | SUPPL. 2 | |
| dc.description | 99 | |
| dc.description | 104 | |
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| dc.description | Ohgami, R.S., Campagna, D.R., Greer, E.L., Antiochos, B., McDonald, A., Chen, J., Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells (2005) Nat Genet, 37 (11), pp. 1264-1269 | |
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| dc.description | Lim, J.E., Jin, O., Bennett, C., Morgan, K., Wang, F., Trenor III, C.C., A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice (2005) Nat Genet, 37 (11), pp. 1270-1273 | |
| dc.language | pt | |
| dc.publisher | | |
| dc.relation | Revista Brasileira de Hematologia e Hemoterapia | |
| dc.rights | aberto | |
| dc.source | Scopus | |
| dc.title | Genetic Causes For Iron Deficiency [causas Genéticas De Deficiência De Ferro] | |
| dc.type | Artículos de revistas | |
