Introduction: Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) often have associated changes in craniofacial morphology and distribution of body fat, either alone or in combination. Aim: To correlate cephalometric and anthropometric measures with OSAHS severity by using the apnea-hypopnea index (AHI). Method: A retrospective cephalometry study of 93 patients with OSAHS was conducted from July 2010 to July 2012. The following measurements were evaluated: body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), the angles formed by the cranial base and the maxilla (SNA) and the mandible (SNB), the difference between SNA and SNB (ANB), the distance from the mandibular plane to the hyoid bone (MP-H), the space between the base of the tongue and the posterior pharyngeal wall (PAS), and the distance between the posterior nasal spine and the tip of the uvula (PNS-P). Means, standard deviations, and Pearson's correlation coefficients were calculated and analyzed. Results: AHI correlated significantly with BMI (r = 0.207, p = 0.047), NC (r = 0.365, p = 0.000), WC (r = 0.337, p = 0.001), PNS-P (r = 0.282, p = 0.006), and MP-H (r = 0.235, p = 0.023). Conclusion: Anthropometric measurements (BMI, NC, and WC) and cephalometric measurements (MP-H and PNS-P) can be used as predictors of OSAHS severity.173321328Force, A.A.O.S.M.T., Sleep-related breathing disorders in adults: Recommendations for syndrome definition and measurement techniques in clinical research (1999) Sleep, 22 (5), pp. 667-689Racionero Casero, M.A., Garcia Rio, F., Pino Garcia, J.M., Prados Sanchez, C., Diaz Lobato, S., Villamor Leon, J., The sleep apnea syndrome as a health problem. An estimation of its prevalence and morbimortality (1999) An Med Interna, 16 (2), pp. 97-102Barthel, S.W., Strome, M., Snoring, obstructive sleep apnea, and surgery (1999) Med Clin North Am., 83 (1), pp. 85-96Pieters, T., Rodenstein, D.O., Therapeutic options in obstructive sleep apnoea: Have we made enough progress? (2001) Sleep Medicine Reviews, 5 (1), pp. 3-6Kapur, V., Blough, D.K., Sandblom, R.E., Hert, R., De Maine, J.B., Sullivan, S.D., The medical cost of undiagnosed sleep apnea (1999) Sleep, 22 (6), pp. 749-755Lindberg, E., Gislason, T., Epidemiology of sleep-related obstructive breathing (2000) Sleep Medicine Reviews, 4 (5), pp. 411-433Powell, N.B., Riley, R.W., Robinson, A., Surgical management of obstructive sleep apnea syndrome (1998) Clin Chest Med., 19 (1), pp. 77-86Riley, R., Guilleminault, C., Herran, J., Powell, N., Cephalometric analyses and flow-volume loops in obstructive sleep apnea patients (1983) Sleep, 6 (4), pp. 303-311Olszewska, E., Sieskiewicz, A., Rozycki, J., Rogalewski, M., Tarasow, E., Rogowski, M., A comparison of cephalometric analysis using radiographs and craniofacial computed tomography in patients with obstructive sleep apnea syndrome: Preliminary report (2009) Eur Arch Otorhinolaryngol., 266, pp. 535-542Julià-Serdà, G., Pérez-Peñate, G., Saavedra-Santana, P., Ponce-González, M., Valencia-Gallardo, J.M., Rodríguez-Delgado, R., Usefulness of cephalometry in sparing polysomnography of patients with suspected obstructive sleep apnea (2006) Sleep Breath., 10 (4), pp. 181-187Bharadwaj, R., Ravikumar, A., Krishnaswamy, N.R., Evaluation of craniofacial morphology in patients with obstructive sleep apnea using lateral cephalometry and dynamic MRI (2011) Indian J Dent Res., 22 (6), pp. 739-748Alvarez, C.M., Lessin, M.E., Gross, P.D., Mandibular advancement combined with horizontal advancement genioplasty for the treatment of obstructive sleep apnea in an edentulous patient. A case report (1987) Oral Surg Oral Med Oral Pathol., 64 (4), pp. 402-406Guilleminault, C., Riley, R., Powell, N., Obstructive sleep apnea and abnormal cephalometric measurements. Implications for treatment (1984) Chest, 86 (5), pp. 793-794Safaya, A., Suri, J.C., The protocol for the diagnosis of obstructive sleep apnea syndrome (1998) IJO & HNS, 50 (1), pp. 46-51Akpinar, M.E., Celikoyar, M.M., Altundag, A., Kocak, I., The comparison of cephalometric characteristics in nonobese obstructive sleep apnea subjects and primary snorers cephalometric measures in nonobese OSA and primary snorers (2011) Eur Arch Otorhinolaryngol., 268 (7), pp. 1053-1059Rose, E., Lehner, M., Staats, R., Jonas, I.E., Cephalometric analysis in patients with obstructive sleep apnea (2002) J Orofac Orthop., 63 (4), pp. 315-324Ogretmenoglu, O., Suslu, A.E., Yucel, O.T., Onerci, T.M., Sahin, A., Body fat composition: A predictive factor for obstructive sleep apnea (2005) Laryngoscope., 115 (8), pp. 1493-1498Davies, R.J., Ali, N.J., Stradling, J.R., Neck circumference and other clinical features in the diagnosis of the obstructive syndrome (1992) Thorax., 47, pp. 101-105Pinto, J.A., Godoy, L.B.M., Marquis, V.W.P.B., Sonego, T.B., Leal, C.F.A., Ártico, M.S., Anthropometric data as predictors of obstructive sleep apnea severity (2011) Braz J Otorhinolaryngol., 77 (4), pp. 516-521Ferguson, K.A., Ono, T., Lowe, A.A., Ryan, C.F., Fleetham, J.A., The relationship between obesity and craniofacial structure in obstructive sleep apnea (1995) Chest, 108 (2), pp. 375-381Schafer, H., Pauleit, D., Sudhop, T., Gouni-Berthold, I., Ewig, S., Berthold, H.K., Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea (2002) Chest, 122 (3), pp. 829-839Montoya, F.S., Bedialauneta, J.R.I., Larracoechea, U.A., Ibarguen, A.M., Del Rey, A.S., Fernandez, J.M.S., The predictive value of clinical and epidemiological parameters in the identification of patients with obstructive sleep apnoea (OSA): A clinical prediction algorithm in the evaluation of OSA (2007) Eur Arch Otorhinolaryngol., 264 (6), pp. 637-643Dixon, J.B., Schachter, L.M., O'Brien, P.E., Predicting sleep apnea and excessive day sleepiness in the severely obese: Indicators for polysomnography (2003) Chest, 123, pp. 1134-1141Martinez-Rivera, C., Abad, J., Fiz, J.A., Rios, J., Morera, J., Usefulness of truncal obesity indices as predictive factors for obstructive sleep apnea syndrome (2008) Obesity (Silver Spring)., 16 (1), pp. 113-118Obesity: Preventing and managing the global epidemic (2000) Report of A WHO Consultation. World Health Organization Technical Report Series, 894, pp. i-xii. , WHO. 1-253Physical status: The use and interpretation of anthropometry (1995) Report of A WHO Expert Committee. World Health Organization Technical Report Series, 854, pp. 1-452. , WHORedline, S., Tishler, P.V., The genetics of sleep apnea (2000) Sleep Med Rev., 4 (6), pp. 583-602Bacon, W.H., Turlot, J.C., Krieger, J., Stierle, J.L., Cephalometric evaluation of pharyngeal obstructive factors in patients with sleep apneas syndrome (1990) Angle Orthod., 60 (2), pp. 115-122Maltais, F., Carrier, G., Cormier, Y., Sériès, F., Cephalometric measurements in snorers, non-snorers, and patients with sleep apnoea (1991) Thorax., 46, pp. 419-423Barvaux, V.A., Aubert, G., Rodenstein, D.O., Weight loss as a treatment for obstructive sleep apnoea (2000) Sleep Medicine Reviews., 4 (5), pp. 435-452Sharma, S.K., Malik, V., Vasudev, C., Banga, A., Mohan, A., Handa, K.K., Prediction of obstructive sleep apnea in patients presenting to a tertiary care center (2006) Sleep Breath., 10 (3), pp. 147-154Davidson, T.M., Patel, M.R., Waist circumference and sleep disordered breathing (2008) Laryngoscope, 118 (2), pp. 339-347Doghramji, K., Jabourian, Z.H., Pilla, M., Farole, A., Lindholm, R.N., Predictors of outcome for uvulopalatopharyngoplasty (1995) Laryngoscope, 105 (3 PART 1), pp. 311-314Series, F., St Pierre, S., Carrier, G., Surgical correction of nasal obstruction in the treatment of mild sleep apnoea: Importance of cephalometry in predicting outcome (1993) Thorax., 48 (4), pp. 360-363Woodson, B.T., Structural effectiveness of pharyngeal sleep apnea surgery (2008) Sleep Medicine Reviews, 12 (6), pp. 463-479Hora, F., Napolis, L.M., Daltro, C., Kodaira, S.K., Tufik, S., Togeiro, S.M., Clinical, anthropometric and upper airway anatomic characteristics of obese patients with obstructive sleep apnea syndrome (2007) Respiration, 74 (5), pp. 517-524Schellenberg, J.B., Maislin, G., Schwab, R.J., Physical findings and risk for obstructive sleep apnea. The importance of oropharyngeal structures (2000) Am J Respir Crit Care Med., 162, pp. 740-748Onat, A., Hergenc, G., Yuksel, H., Can, G., Ayhan, E., Kaya, Z., Neck circumference as a measure of central obesity: Associations with metabolic syndrome and obstructive sleep apnea syndrome beyond waist circumference (2009) Clin Nutr., 28 (1), pp. 46-51. , Epub 2008/11/18Hoffstein, V., Mateika, S., Differences in abdominal and neck circumferences in patients with and without obstructive sleep apnoea (1992) Eur Respir J., 5 (4), pp. 377-381Partinen, M., Guilleminault, C., Quera-Salva, M., Jamieson, A., Obstructive sleep apnea and cephalometric roentgenograms. The role of anatomic upper airway abnormalities in the definition of abnormal breathing during sleep (1988) Chest, 93 (6), pp. 1199-1205Yucel, A., Unlu, M., Haktanir, A., Acar, M., Fidan, F., Evaluation of the upper airway cross-sectional area changes in different degrees of severity of obstructive sleep apnea syndrome: Cephalometric and dynamic CT study (2005) AJNR Am J Neuroradiol., 26 (10), pp. 2624-2629Mayer, P., Pépin, J.L., Bettega, G., Veale, D., Ferretti, G., Deschaux, C., Relationship between body mass index, age and upper airway measurements in snorers and sleep apnoea patients (1996) Eur Respir J., 9 (9), pp. 1801-1809Davies, R., Stradling, The relationship between neck circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome (1990) Eur Respir J., 3 (5), pp. 509-514Katz, I., Stradling, J., Sljutsky, A.S., Zamel, N., Hoffstein, V., Do patients with obstructive sleep apnea have thick necks? (1990) Am Rev Respir Dis., 141 (5 PART 1), pp. 1228-1231Young, T., Peppard, P.E., Taheri, S., Excess weight and sleep-disordered breathing (2005) J Appl Physiol., 99, pp. 1592-1599Julia-Serda, G., Perez-Penate, G., Saavedra-Santana, P., Ponce-Gonzalez, M., Valencia-Gallardo, J.M., Rodriguez-Delgado, R., Usefulness of cephalometry in sparing polysomnography of patients with suspected obstructive sleep apnea (2006) Sleep Breath., 10 (4), pp. 181-187Katz, I., Stradling, J., Slutsky, A.S., Zamel, N., Hoffstein, V., Do patients with obstructive sleep apnea have thick necks? (1990) The American Review of Respiratory Disease, 141 (5 PART 1), pp. 1228-1231De Tarso Moura Borges, P., Paschoal, J.R., Initial indication of treatment in 60 patients with sleep obstructive ventilatory disturbance (2005) Braz J Otorhinolaryngol., 71 (6), pp. 740-746Millman, R.P., Carlisle, C.C., Eveloff, S.E., McGarvey, S.T., Levinson, P.D., Body fat distribution and sleep apnea severity in women (1995) Chest, 107 (2), pp. 362-366