dc.creatorDa Silva Filho L.V.R.F.
dc.creatorFerreira F.A.
dc.creatorReis F.J.C.
dc.creatorDe Britto M.C.A.
dc.creatorLevy C.E.
dc.creatorClark O.
dc.creatorRibeiro J.D.
dc.date2013
dc.date2015-06-25T19:09:57Z
dc.date2015-11-26T14:56:56Z
dc.date2015-06-25T19:09:57Z
dc.date2015-11-26T14:56:56Z
dc.date.accessioned2018-03-28T22:08:52Z
dc.date.available2018-03-28T22:08:52Z
dc.identifier
dc.identifierJornal Brasileiro De Pneumologia. , v. 39, n. 4, p. 495 - 512, 2013.
dc.identifier18063713
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84884733385&partnerID=40&md5=e3899ff4cbe12cc1303a267155ec38df
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/88406
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/88406
dc.identifier2-s2.0-84884733385
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1255557
dc.descriptionEvidence-based techniques have been increasingly used in the creation of clinical guidelines and the development of recommendations for medical practice. The use of levels of evidence allows the reader to identify the quality of scientific information that supports the recommendations made by experts. The objective of this review was to address current concepts related to the clinical impact, diagnosis, and treatment of Pseudomonas aeruginosa infections in patients with cystic fibrosis. For the preparation of this review, the authors defined a group of questions that would be answered in accordance with the principles of PICO-an acronym based on questions regarding the Patients of interest, Intervention being studied, Comparison of the intervention, and Outcome of interest. For each question, a structured review of the literature was performed using the Medline database in order to identify the studies with the methodological design most appropriate to answering the question. The questions were designed so that each of the authors could write a response. A first draft was prepared and discussed by the group. Recommendations were then made on the basis of the level of scientific evidence, in accordance with the classification system devised by the Oxford Centre for Evidence-Based Medicine, as well as the level of agreement among the members of the group.
dc.description39
dc.description4
dc.description495
dc.description512
dc.descriptionRatjen, F., Döring, G., Cystic fibrosis (2003) Lancet, 361 (9358), pp. 681-689. , http://dx.doi.org/10.1016/S0140-6736(03)12567-6
dc.descriptionFlume, P.A., O'Sullivan, B.P., Robinson, K.A., Goss, C.H., Mogayzel Jr., P.J., Willey-Courand, D.B., Cystic fibrosis pulmonary guidelines: Chronic medications for maintenance of lung health (2007) Am J Respir Crit Care Med, 176 (10), pp. 957-969. , http://dx.doi.org/10.1164/rccm.200705-664OC, PMid:17761616
dc.descriptionRatjen, F.A., Cystic fibrosis: Pathogenesis and future treatment strategies (2009) Respir Care, 54 (5), pp. 595-605. , http://dx.doi.org/10.4187/aarc0427, PMid:19393104
dc.descriptionLommatzsch, S.T., Aris, R., Genetics of cystic fibrosis (2009) Semin Respir Crit Care Med, 30 (5), pp. 531-538. , http://dx.doi.org/10.1055/s-0029-1238911, PMid:19760540
dc.descriptionRatjen, F., Diagnosing and managing infection in CF Paediatr Respir Rev. 2006;7 Suppl, 1, pp. 151-153. , http://dx.doi.org/10.1016/j.prrv.2006.04.217, PMid:16798546
dc.descriptionGovan, J.R., Deretic, V., Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia (1996) Microbiol Rev, 60 (3), pp. 539-574. , PMid:8840786 PMCid:239456
dc.descriptionLi, Z., Kosorok, M.R., Farrell, P.M., Laxova, A., West, S.E., Green, C.G., Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis (2005) JAMA, 293 (5), pp. 581-588. , http://dx.doi.org/10.1001/jama.293.5.581, PMid:15687313
dc.descriptionGibson, R.L., Burns, J.L., Ramsey, B.W., Pathophysiology and management of pulmonary infections in cystic fibrosis (2003) Am J Respir Crit Care Med, 168 (8), pp. 918-951. , http://dx.doi.org/10.1164/rccm.200304-505SO, PMid:14555458
dc.descriptionDeschaght, P., van Daele, S., de Baets, F., Vaneechoutte, M., PCR and the detection of Pseudomonas aeruginosa in respiratory samples of CF patients. A literature review (2011) J Cyst Fibros, 10 (5), pp. 293-297. , http://dx.doi.org/10.1016/j.jcf.2011.05.004, PMid:21684819
dc.descriptionNixon, G.M., Armstrong, D.S., Carzino, R., Carlin, J.B., Olinsky, A., Robertson, C.F., Clinical outcome after early Pseudomonas aeruginosa infection in cystic fibrosis (2001) J Pediatr, 138 (5), pp. 699-704. , http://dx.doi.org/10.1067/mpd.2001.112897, PMid:11343046
dc.descriptionHenry, R.L., Mellis, C.M., Petrovic, L., Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis (1992) Pediatr Pulmonol, 12 (3), pp. 158-161. , http://dx.doi.org/10.1002/ppul.1950120306, PMid:1641272
dc.descriptionTaccetti, G., Campana, S., Festini, F., Mascherini, M., Döring, G., Early eradication therapy against Pseudomonas aeruginosa in cystic fibrosis patients (2005) Eur Respir J, 26 (3), pp. 458-461. , http://dx.doi.org/10.1183/09031936.05.00009605, PMid:16135728
dc.descriptionThe Oxford 2011 Levels of Evidence, , http://www.cebm.net/index.aspx?o=5653, CEBM Centre For Evidence Based Medicine [homepage on the Internet]. Oxford: University of Oxford. [cited 2013 Feb 11]
dc.descriptionLee, T.W., Brownlee, K.G., Conway, S.P., Denton, M., Littlewood, J.M., Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients (2003) J Cyst Fibros, 2 (1), pp. 29-34. , http://dx.doi.org/10.1016/S1569-1993(02)00141-8
dc.descriptionCorey, M., Survival estimates in cystic fibrosis: Snapshots of a moving target (1996) Pediatr Pulmonol, 21 (3), pp. 149-150. , http://dx.doi.org/10.1002/1099-0496(199603)21:3149::AID-PPUL19502103023.0.CO;2-C
dc.descriptionHudson, V.L., Wielinski, C.L., Regelmann, W.E., Prognostic implications of initial oropharyngeal bacterial flora in patients with cystic fibrosis diagnosed before the age of two years (1993) J Pediatr, 122 (6), pp. 854-860. , http://dx.doi.org/10.1016/S0022-3476(09)90007-5
dc.descriptionKosorok, M.R., Zeng, L., West, S.E., Rock, M.J., Splaingard, M.L., Laxova, A., Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition (2001) Pediatr Pulmonol, 32 (4), pp. 277-287. , http://dx.doi.org/10.1002/ppul.2009.abs, PMid:11568988
dc.descriptionEmerson, J., Rosenfeld, M., McNamara, S., Ramsey, B., Gibson, R.L., Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis (2002) Pediatr Pulmonol, 34 (2), pp. 91-100. , http://dx.doi.org/10.1002/ppul.10127, PMid:12112774
dc.descriptionLebecque, P., Leal, T., Zylberberg, K., Reychler, G., Bossuyt, X., Godding, V., Towards zero prevalence of chronic Pseudomonas aeruginosa infection in children with cystic fibrosis (2006) J Cyst Fibros, 5 (4), pp. 237-244. , http://dx.doi.org/10.1016/j.jcf.2006.04.001, PMid:16790367
dc.descriptionRatjen, F., Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis (2006) Curr Opin Pulm Med, 12 (6), pp. 428-432. , http://dx.doi.org/10.1097/01.mcp.0000245712.51514.a1, PMid:17053493
dc.descriptionEqui, A.C., Pike, S.E., Davies, J., Bush, A., Use of cough swabs in a cystic fibrosis clinic (2001) Arch Dis Child, 85 (5), pp. 438-439. , http://dx.doi.org/10.1136/adc.85.5.438, PMid:11668115 PMCid:1718986
dc.descriptionDa Silva Filho, L.V., Tateno, A.F., Martins, K.M., Azzuz Chernishev, A.C., de Garcia, D.O., Haug, M., The combination of PCR and serology increases the diagnosis of Pseudomonas aeruginosa colonization/infection in cystic fibrosis (2007) Pediatr Pulmonol, 42 (10), pp. 938-944. , http://dx.doi.org/10.1002/ppul.20686, PMid:17722007
dc.descriptionHoiby, N., Flensborg, E.W., Beck, B., Friis, B., Jacobsen, S.V., Jacobsen, L., Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic and prognostic significance of Pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis (1977) Scand J Respir Dis, 58 (2), pp. 65-79. , PMid:404701
dc.descriptionBrett, M.M., Ghoneim, A.T., Littlewood, J.M., Prediction and diagnosis of early Pseudomonas aeruginosa infection in cystic fibrosis: A follow-up study (1988) J Clin Microbiol, 26 (8), pp. 1565-1570. , Erratum in: J Clin Microbiol 1989;27(1):230. PMid:3139707 PMCid:266661
dc.descriptionWest, S.E., Zeng, L., Lee, B.L., Kosorok, M.R., Laxova, A., Rock, M.J., Respiratory infections with Pseudomonas aeruginosa in children with cystic fibrosis: Early detection by serology and assessment of risk factors (2002) JAMA, 287 (22), pp. 2958-2967. , http://dx.doi.org/10.1001/jama.287.22.2958, PMid:12052125
dc.descriptionKappler, M., Kraxner, A., Reinhardt, D., Ganster, B., Griese, M., Lang, T., Diagnostic and prognostic value of serum antibodies against Pseudomonas aeruginosa in cystic fibrosis (2006) Thorax, 61 (8), pp. 684-688. , http://dx.doi.org/10.1136/thx.2005.049536, PMid:16449259 PMCid:2104684
dc.descriptionTramper-Stranders, G.A., van der Ent, C.K., Slieker, M.G., Terheggen-Lagro, S.W., Teding van Berkhout, F., Kimpen, J.L., Diagnostic value of serological tests against Pseudomonas aeruginosa in a large cystic fibrosis population (2006) Thorax, 61 (8), pp. 689-693. , http://dx.doi.org/10.1136/thx.2005.054726, PMid:16601093 PMCid:2104678
dc.descriptionRatjen, F., Walter, H., Haug, M., Meisner, C., Grasemann, H., Döring, G., Diagnostic value of serum antibodies in early Pseudomonas aeruginosa infection in cystic fibrosis patients (2007) Pediatr Pulmonol, 42 (3), pp. 249-255. , http://dx.doi.org/10.1002/ppul.20562, PMid:17243185
dc.descriptionWeisner, A.M., Chart, H., Bush, A., Davies, J.C., Pitt, T.L., Detection of antibodies to Pseudomonas aeruginosa in serum and oral fluid from patients with cystic fibrosis (2007) J Med Microbiol, 56 (PART 5), pp. 670-674. , http://dx.doi.org/10.1099/jmm.0.46833-0, PMid:17446292
dc.descriptionPressler, T., Karpati, F., Granström, M., Knudsen, P.K., Lindblad, A., Hjelte, L., Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods (2009) J Cyst Fibros, 8 (1), pp. 37-42. , http://dx.doi.org/10.1016/j.jcf.2008.08.002, PMid:18835753
dc.descriptionMilagres, L.G., Castro, T.L., Garcia, D., Cruz, A.C., Higa, L., Folescu, T., Antibody response to Pseudomonas aeruginosa in children with cystic fibrosis (2009) Pediatr Pulmonol, 44 (4), pp. 392-401. , http://dx.doi.org/10.1002/ppul.21022, PMid:19283764
dc.descriptionHayes Jr., D., Farrell, P.M., Li, Z., West, S.E., Pseudomonas aeruginosa serological analysis in young children with cystic fibrosis diagnosed through newborn screening (2010) Pediatr Pulmonol, 45 (1), pp. 55-61. , http://dx.doi.org/10.1002/ppul.21083, PMid:20025049 PMCid:2924665
dc.descriptionDouglas, T.A., Brennan, S., Berry, L., Winfield, K., Wainwright, C.E., Grimwood, K., Value of serology in predicting Pseudomonas aeruginosa infection in young children with cystic fibrosis (2010) Thorax, 65 (11), pp. 985-990. , http://dx.doi.org/10.1136/thx.2009.132845, PMid:20889526
dc.descriptionWainwright, C.E., Vidmar, S., Armstrong, D.S., Byrnes, C.A., Carlin, J.B., Cheney, J., Effect of bronchoalveolar lavage-directed therapy on Pseudomonas aeruginosa infection and structural lung injury in children with cystic fibrosis: A randomized trial (2011) JAMA, 306 (2), pp. 163-171. , http://dx.doi.org/10.1001/jama.2011.954, PMid:21750293
dc.descriptionLittlewood, J.M., Miller, M.G., Ghoneim, A.T., Ramsden, C.H., Nebulised colomycin for early pseudomonas colonisation in cystic fibrosis (1985) Lancet, 1 (8433), p. 865. , http://dx.doi.org/10.1016/S0140-6736(85)92222-6
dc.descriptionValerius, N.H., Koch, C., Høiby, N., Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment (1991) Lancet, 338 (8769), pp. 725-726. , http://dx.doi.org/10.1016/0140-6736(91)91446-2
dc.descriptionMunck, A., Bonacorsi, S., Mariani-Kurkdjian, P., Lebourgeois, M., Gérardin, M., Brahimi, N., Genotypic characterization of Pseudomonas aeruginosa strains recovered from patients with cystic fibrosis after initial and subsequent colonization (2001) Pediatr Pulmonol, 32 (4), pp. 288-292. , http://dx.doi.org/10.1002/ppul.1121, PMid:11568989
dc.descriptionGibson, R.L., Emerson, J., McNamara, S., Burns, J.L., Rosenfeld, M., Yunker, A., Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis (2003) Am J Respir Crit Care Med, 167 (6), pp. 841-849. , http://dx.doi.org/10.1164/rccm.200208-855OC, PMid:12480612
dc.descriptionDavidson, A.G., Chilvers, M.A., Lillquist, Y.P., Effects of a Pseudomonas aeruginosa eradication policy in a cystic fibrosis clinic (2012) Curr Opin Pulm Med, 18 (6), pp. 615-621. , http://dx.doi.org/10.1097/MCP.0b013e328358f5a2, PMid:22990661
dc.descriptionRatjen, F., Munck, A., Kho, P., Angyalosi, G., ELITE Study Group. Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: The ELITE trial (2010) Thorax, 65 (4), pp. 286-291. , http://dx.doi.org/10.1136/thx.2009.121657, PMid:19996339
dc.descriptionTreggiari, M.M., Retsch-Bogart, G., Mayer-Hamblett, N., Khan, U., Kulich, M., Kronmal, R., Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis (2011) Arch Pediatr Adolesc Med, 165 (9), pp. 847-856. , http://dx.doi.org/10.1001/archpediatrics.2011.136, PMid:21893650
dc.descriptionLangton Hewer, S.C., Smyth, A.R., Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis (2009) Cochrane Database Syst Rev, (4), pp. CD004197. , PMid:19821321
dc.descriptionCollaco, J.M., Green, D.M., Cutting, G.R., Naughton, K.M., Mogayzel Jr., P.J., Location and duration of treatment of cystic fibrosis respiratory exacerbations do not affect outcomes (2010) Am J Respir Crit Care Med, 182 (9), pp. 1137-1143. , http://dx.doi.org/10.1164/rccm.201001-0057OC, PMid:20581166 PMCid:3001256
dc.descriptionFuchs, H.J., Borowitz, D.S., Christiansen, D.H., Morris, E.M., Nash, M.L., Ramsey, B.W., Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group (1994) N Engl J Med, 331 (10), pp. 637-642. , http://dx.doi.org/10.1056/NEJM199409083311003, PMid:7503821
dc.descriptionRosenfeld, M., Emerson, J., Williams-Warren, J., Pepe, M., Smith, A., Montgomery, A.B., Defining a pulmonary exacerbation in cystic fibrosis (2001) J Pediatr, 139 (3), pp. 359-365. , http://dx.doi.org/10.1067/mpd.2001.117288, PMid:11562614
dc.descriptionDakin, C., Henry, R.L., Field, P., Morton, J., Defining an exacerbation of pulmonary disease in cystic fibrosis (2001) Pediatr Pulmonol, 31 (6), pp. 436-442. , http://dx.doi.org/10.1002/ppul.1072, PMid:11389576
dc.descriptionFlume, P.A., Mogayzel Jr., P.J., Robinson, K.A., Goss, C.H., Rosenblatt, R.L., Kuhn, R.J., Cystic fibrosis pulmonary guidelines: Treatment of pulmonary exacerbations (2009) Am J Respir Crit Care Med, 180 (9), pp. 802-808. , http://dx.doi.org/10.1164/rccm.200812-1845PP, PMid:19729669
dc.descriptionStenbit, A.E., Flume, P.A., Pulmonary exacerbations in cystic fibrosis (2011) Curr Opin Pulm Med, 17 (6), pp. 442-447. , PMid:21881509
dc.descriptionBilton, D., Canny, G., Conway, S., Dumcius, S., Hjelte, L., Proesmans, M., Pulmonary exacerbation: Towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials (2011) J Cyst Fibros, 10 (SUPPL. 2), pp. 79-81. , http://dx.doi.org/10.1016/S1569-1993(11)60012-X
dc.descriptionBalaguer, A., De Dios, G.J., Home versus hospital intravenous antibiotic therapy for cystic fibrosis (2012) Cochrane Database Syst Rev, 3, pp. CD001917. , PMid:22419283
dc.descriptionSmyth, A., Elborn, J.S., Exacerbations in cystic fibrosis: 3. Management (2008) Thorax, 63 (2), pp. 180-184. , http://dx.doi.org/10.1136/thx.2006.060905, PMid:18234661
dc.descriptionSmyth, A., Knox, A., Twice vs three times daily antibiotics in the treatment of pulmonary exacerbations of cystic fibrosis (2011) J Cyst Fibros, 10 (5), p. 383. , http://dx.doi.org/10.1016/j.jcf.2011.03.010, PMid:21507733
dc.descriptionBreidenstein, E.B., de la Fuente-Nú-ez, C., Hancock, R.E., Pseudomonas aeruginosa: All roads lead to resistance (2011) Trends Microbiol, 19 (8), pp. 419-426. , http://dx.doi.org/10.1016/j.tim.2011.04.005, PMid:21664819
dc.descriptionCheng, K., Smyth, R.L., Govan, J.R., Doherty, C., Winstanley, C., Denning, N., Spread of beta-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic (1996) Lancet, 348 (9028), pp. 639-642. , http://dx.doi.org/10.1016/S0140-6736(96)05169-0
dc.descriptionElphick, H.E., Tan, A., Single versus combination intravenous antibiotic therapy for people with cystic fibrosis (2005) Cochrane Database Syst Rev, (2), pp. CD002007. , PMid:15846627
dc.descriptionBosso, J.A., Saxon, B.A., Matsen, J.M., Comparative activity of cefepime, alone and in combination, against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients (1991) Antimicrob Agents Chemother, 35 (4), pp. 783-784. , http://dx.doi.org/10.1128/AAC.35.4.783, PMid:1906264 PMCid:245101
dc.descriptionTré-Hardy, M., Nagant, C., El-Manssouri, N., Vanderbist, F., Traore, H., Vaneechoutte, M., Efficacy of the combination of tobramycin and a macrolide in an in vitro Pseudomonas aeruginosa mature biofilm model (2010) Antimicrob Agents Chemother, 54 (10), pp. 4409-4415. , http://dx.doi.org/10.1128/AAC.00372-10, PMid:20696878 PMCid:2944582
dc.descriptionLeroy, A., Humbert, G., Oksenhendler, G., Fillastre, J.P., Pharmacokinetics of aminoglycosides in subjects with normal and impaired renal function (1978) Antibiot Chemother, 25, pp. 163-180. , PMid:352252
dc.descriptionKovarik, J.M., Hoepelman, I.M., Verhoef, J., Once-daily aminoglycoside administration: New strategies for an old drug (1989) Eur J Clin Microbiol Infect Dis, 8 (9), pp. 761-769. , http://dx.doi.org/10.1007/BF02185842, PMid:2512146
dc.descriptionFreeman, C.D., Nicolau, D.P., Belliveau, P.P., Nightingale, C.H., Once-daily dosing of aminoglycosides: Review and recommendations for clinical practice (1997) J Antimicrob Chemother, 39 (6), pp. 677-686. , http://dx.doi.org/10.1093/jac/39.6.677, PMid:9222035
dc.descriptionContopoulos-Ioannidis, D.G., Giotis, N.D., Baliatsa, D.V., Ioannidis, J.P., Extended-interval aminoglycoside administration for children: A meta-analysis (2004) Pediatrics, 114 (1), pp. 111-118. , http://dx.doi.org/10.1542/peds.114.1.e111, PMid:15231982
dc.descriptionSmyth, A.R., Bhatt, J., Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis (2012) Cochrane Database Syst Rev, 2, pp. CD002009. , PMid:22336782
dc.descriptionPlummer, A., Wildman, M., Duration of intravenous antibiotic therapy in people with cystic fibrosis (2011) Cochrane Database Syst Rev, 1, pp. CD006682. , PMid:21249681
dc.descriptionVandevanter, D.R., O'Riordan, M.A., Blumer, J.L., Konstan, M.W., Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations (2010) Respir Res, 11, p. 137. , http://dx.doi.org/10.1186/1465-9921-11-137, PMid:20925941 PMCid:2959026
dc.descriptionHodson, M.E., Penketh, A.R., Batten, J.C., Aerosol carbenicillin and gentamicin treatment of Pseudomonas aeruginosa infection in patients with cystic fibrosis (1981) Lancet, 2 (8256), pp. 1137-1139. , http://dx.doi.org/10.1016/S0140-6736(81)90588-2
dc.descriptionSzaff, M., Høiby, N., Flensborg, E.W., Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection (1983) Acta Paediatr Scand, 72 (5), pp. 651-657. , http://dx.doi.org/10.1111/j.1651-2227.1983.tb09789.x, PMid:6637463
dc.descriptionRamsey, B.W., Dorkin, H.L., Eisenberg, J.D., Gibson, R.L., Harwood, I.R., Kravitz, R.M., Efficacy of aerosolized tobramycin in patients with cystic fibrosis (1993) N Engl J Med, 328 (24), pp. 1740-1746. , http://dx.doi.org/10.1056/NEJM199306173282403, PMid:8497284
dc.descriptionRamsey, B.W., Pepe, M.S., Quan, J.M., Otto, K.L., Montgomery, A.B., Williams-Warren, J., Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group (1999) N Engl J Med, 340 (1), pp. 23-30. , http://dx.doi.org/10.1056/NEJM199901073400104, PMid:9878641
dc.descriptionMaclusky, I.B., Gold, R., Corey, M., Levison, H., Long-term effects of inhaled tobramycin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa (1989) Pediatr Pulmonol, 7 (1), pp. 42-48. , http://dx.doi.org/10.1002/ppul.1950070110, PMid:2505216
dc.descriptionMurphy, T.D., Anbar, R.D., Lester, L.A., Nasr, S.Z., Nickerson, B., Vandevanter, D.R., Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease (2004) Pediatr Pulmonol, 38 (4), pp. 314-320. , http://dx.doi.org/10.1002/ppul.20097, PMid:15334509
dc.description(2009) Antibiotic Treatment For Cystic Fibrosis, , https://www.cysticfibrosis.org.uk/media/82010/CD_Antibiotic_treatment_for_CF_May_09.pdf, Cystic Fibrosis Trust [homepage on the Internet]. Bromley: Cystic Fibrosis Trust. [cited 2013 Feb 11], [Adobe Acrobat document, 102p.]
dc.descriptionHodson, M.E., Gallagher, C.G., Govan, J.R., A randomised clinical trial of nebulised tobramycin or colistin in cystic fibrosis (2002) Eur Respir J, 20 (3), pp. 658-664. , http://dx.doi.org/10.1183/09031936.02.00248102, PMid:12358344
dc.descriptionMcCoy, K.S., Quittner, A.L., Oermann, C.M., Gibson, R.L., Retsch-Bogart, G.Z., Montgomery, A.B., Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis (2008) Am J Respir Crit Care Med, 178 (9), pp. 921-928. , http://dx.doi.org/10.1164/rccm.200712-1804OC, PMid:18658109 PMCid:2577727
dc.descriptionOermann, C.M., Retsch-Bogart, G.Z., Quittner, A.L., Gibson, R.L., McCoy, K.S., Montgomery, A.B., An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis (2010) Pediatr Pulmonol, 45 (11), pp. 1121-1134. , http://dx.doi.org/10.1002/ppul.21301, PMid:20672296
dc.descriptionKonstan, M.W., Flume, P.A., Kappler, M., Chiron, R., Higgins, M., Brockhaus, F., Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial (2011) J Cyst Fibros, 10 (1), pp. 54-61. , http://dx.doi.org/10.1016/j.jcf.2010.10.003, PMid:21075062
dc.descriptionGeller, D.E., Flume, P.A., Staab, D., Fischer, R., Loutit, J.S., Conrad, D.J., Levofloxacin inhalation solution (MP-376) in patients with cystic fibrosis with Pseudomonas aeruginosa (2011) Am J Respir Crit Care Med, 183 (11), pp. 1510-1516. , http://dx.doi.org/10.1164/rccm.201008-1293OC, PMid:21471106
dc.descriptionRyan, G., Singh, M., Dwan, K., Inhaled antibiotics for long-term therapy in cystic fibrosis (2011) Cochrane Database Syst Rev, (3), pp. CD001021
dc.descriptionSawicki, G.S., Tiddens, H., Managing treatment complexity in cystic fibrosis: Challenges and opportunities (2012) Pediatr Pulmonol, 47 (6), pp. 523-533. , http://dx.doi.org/10.1002/ppul.22546, PMid:22467341
dc.descriptionRobinson, P., Cystic fibrosis (2001) Thorax, 56 (3), pp. 237-241. , http://dx.doi.org/10.1136/thorax.56.3.237, PMid:11182019 PMCid:1758774
dc.descriptionBell, S.C., Robinson, P.J., Exacerbations in cystic fibrosis: 2. prevention (2007) Thorax, 62 (8), pp. 723-732. , http://dx.doi.org/10.1136/thx.2006.060897, PMid:17687099 PMCid:2117269
dc.descriptionSawicki, G.S., Sellers, D.E., Robinson, W.M., High treatment burden in adults with cystic fibrosis: Challenges to disease self-management (2009) J Cyst Fibros, 8 (2), pp. 91-96. , http://dx.doi.org/10.1016/j.jcf.2008.09.007, PMid:18952504 PMCid:2680350
dc.descriptionMilgrom, H., Bender, B., Ackerson, L., Bowry, P., Smith, B., Rand, C., Noncompliance and treatment failure in children with asthma (1996) J Allergy Clin Immunol, 98 (6 PART 1), pp. 1051-1057. , http://dx.doi.org/10.1016/S0091-6749(96)80190-4
dc.descriptionIevers, C.E., Brown, R.T., Drotar, D., Caplan, D., Pishevar, B.S., Lambert, R.G., Knowledge of physician prescriptions and adherence to treatment among children with cystic fibrosis and their mothers (1999) J Dev Behav Pediatr, 20 (5), pp. 335-343. , http://dx.doi.org/10.1097/00004703-199910000-00008, PMid:10533992
dc.descriptionRau, J.L., Determinants of patient adherence to an aerosol regimen (2005) Respir Care, 50 (10), pp. 1346-1356. , discussion 1357-9. PMid:16185370
dc.descriptionDigirolamo, A.M., Quittner, A.L., Ackerman, V., Stevens, J., Identification and assessment of ongoing stressors in adolescents with a chronic illness: An application of the behavior-analytic model (1997) J Clin Child Psychol, 26 (1), pp. 53-66. , http://dx.doi.org/10.1207/s15374424jccp2601_6, PMid:9118176
dc.descriptionGudas, L.J., Koocher, G.P., Wypij, D., Perceptions of medical compliance in children and adolescents with cystic fibrosis (1991) J Dev Behav Pediatr, 12 (4), pp. 236-242. , http://dx.doi.org/10.1097/00004703-199108000-00004, PMid:1939678
dc.descriptionModi, A.C., Quittner, A.L., Barriers to treatment adherence for children with cystic fibrosis and asthma: What gets in the way? (2006) J Pediatr Psychol, 31 (8), pp. 846-858. , http://dx.doi.org/10.1093/jpepsy/jsj096, PMid:16401680
dc.descriptionDalcin Pde, T., Rampon, G., Pasin, L.R., Ramon, G.M., Abrahão, C.L., Oliveira, V.Z., Adherence to treatment in patients with cystic fibrosis (2007) J Bras Pneumol, 33 (6), pp. 663-670. , PMid:18200366
dc.descriptionEakin, M.N., Bilderback, A., Boyle, M.P., Mogayzel, P.J., Riekert, K.A., Longitudinal association between medication adherence and lung health in people with cystic fibrosis (2011) J Cyst Fibros, 10 (4), pp. 258-264. , http://dx.doi.org/10.1016/j.jcf.2011.03.005, PMid:21458391 PMCid:3114200
dc.descriptionBriesacher, B.A., Quittner, A.L., Saiman, L., Sacco, P., Fouayzi, H., Quittell, L.M., Adherence with tobramycin inhaled solution and health care utilization (2011) BMC Pulm Med, 11, p. 5. , http://dx.doi.org/10.1186/1471-2466-11-5, PMid:21251275 PMCid:3033861
dc.descriptionShinkai, M., Rubin, B.K., Macrolides and airway inflammation in children (2005) Paediatr Respir Rev, 6 (3), pp. 227-235. , http://dx.doi.org/10.1016/j.prrv.2005.06.005, PMid:16153572
dc.descriptionKudoh, S., Uetake, T., Hagiwara, K., Hirayama, M., Hus, L.H., Kimura, H., Clinical effects of low-dose long-term erythromycin chemotherapy on diffuse panbronchiolitis (1987) Nihon Kyobu Shikkan Gakkai Zasshi, 25 (6), pp. 632-642. , Article in Japanese, PMid:3682440
dc.descriptionMcArdle, J.R., Talwalkar, J.S., Macrolides in cystic fibrosis (2007) Clin Chest Med, 28 (2), pp. 347-360. , http://dx.doi.org/10.1016/j.ccm.2007.02.005, PMid:17467553
dc.descriptionEqui, A., Balfour-Lynn, I.M., Bush, A., Rosenthal, M., Long term azithromycin in children with cystic fibrosis: A randomised, placebo-controlled crossover trial (2002) Lancet, 360 (9338), pp. 978-984. , http://dx.doi.org/10.1016/S0140-6736(02)11081-6
dc.descriptionSaiman, L., Marshall, B.C., Mayer-Hamblett, N., Burns, J.L., Quittner, A.L., Cibene, D.A., Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: A randomized controlled trial (2003) JAMA, 290 (13), pp. 1749-1756. , http://dx.doi.org/10.1001/jama.290.13.1749, PMid:14519709
dc.descriptionSaiman, L., Anstead, M., Mayer-Hamblett, N., Lands, L.C., Kloster, M., Hocevar-Trnka, J., Effect of azithromycin on pulmonary function in patients with cystic fibrosis uninfected with Pseudomonas aeruginosa: A randomized controlled trial (2010) JAMA, 303 (17), pp. 1707-1715. , http://dx.doi.org/10.1001/jama.2010.563, PMid:20442386
dc.descriptionCai, Y., Chai, D., Wang, R., Bai, N., Liang, B.B., Liu, Y., Effectiveness and safety of macrolides in cystic fibrosis patients: A meta-analysis and systematic review (2011) J Antimicrob Chemother, 66 (5), pp. 968-978. , http://dx.doi.org/10.1093/jac/dkr040, PMid:21393178
dc.descriptionSouthern, K.W., Barker, P.M., Solis-Moya, A., Patel, L., Macrolide antibiotics for cystic fibrosis (2011) Cochrane Database Syst Rev, (12), pp. CD002203. , PMid:22161368
dc.descriptionSmith, A.L., Fiel, S.B., Mayer-Hamblett, N., Ramsey, B., Burns, J.L., Susceptibility testing of Pseudomonas aeruginosa isolates and clinical response to parenteral antibiotic administration: Lack of association in cystic fibrosis (2003) Chest, 123 (5), pp. 1495-1502. , http://dx.doi.org/10.1378/chest.123.5.1495, PMid:12740266
dc.descriptionAaron, S.D., Vandemheen, K.L., Ferris, W., Fergusson, D., Tullis, E., Haase, D., Combination antibiotic susceptibility testing to treat exacerbations of cystic fibrosis associated with multiresistant bacteria: A randomised, double-blind, controlled clinical trial (2005) Lancet, 366 (9484), pp. 463-471. , http://dx.doi.org/10.1016/S0140-6736(05)67060-2
dc.descriptionCantón, R., Cobos, N., de Gracia, J., Baquero, F., Honorato, J., Gartner, S., Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients (2005) Clin Microbiol Infect, 11 (9), pp. 690-703. , http://dx.doi.org/10.1111/j.1469-0691.2005.01217.x, PMid:16104983
dc.descriptionSaiman, L., Mehar, F., Niu, W.W., Neu, H.C., Shaw, K.J., Miller, G., Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantation (1996) Clin Infect Dis, 23 (3), pp. 532-537. , http://dx.doi.org/10.1093/clinids/23.3.532, PMid:8879776
dc.descriptionMerlo, C.A., Boyle, M.P., Diener-West, M., Marshall, B.C., Goss, C.H., Lechtzin, N., Incidence and risk factors for multiple antibiotic-resistant Pseudomonas aeruginosa in cystic fibrosis (2007) Chest, 132 (2), pp. 562-568. , http://dx.doi.org/10.1378/chest.06-2888, PMid:17646236
dc.descriptionLechtzin, N., John, M., Irizarry, R., Merlo, C., Diette, G.B., Boyle, M.P., Outcomes of adults with cystic fibrosis infected with antibiotic-resistant Pseudomonas aeruginosa (2006) Respiration, 73 (1), pp. 27-33. , http://dx.doi.org/10.1159/000087686, PMid:16113513
dc.languageen
dc.languagept
dc.publisher
dc.relationJornal Brasileiro de Pneumologia
dc.rightsaberto
dc.sourceScopus
dc.titlePseudomonas Aeruginosa Infection In Patients With Cystic Fibrosis: Scientific Evidence Regarding Clinical Impact, Diagnosis, And Treatment [infecção Por Pseudomonas Aeruginosa Em Pacientes Com Fibrose Cística: Evidências Científicas Sobre O Impacto Clínico, Diagnóstico E Tratamento]
dc.typeArtículos de revistas


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