Quality Of Life And Adverse Events After Radiotherapy In Gynecologic Cancer Survivors: A Cohort Study

dc.creatorVaz A.F.
dc.creatorConde D.M.
dc.creatorCosta-Paiva L.
dc.creatorMorais S.S.
dc.creatorEsteves S.B.
dc.creatorPinto-Neto A.M.
dc.date2011
dc.date2015-06-30T20:41:28Z
dc.date2015-11-26T14:53:13Z
dc.date2015-06-30T20:41:28Z
dc.date2015-11-26T14:53:13Z
dc.date.accessioned2018-03-28T22:05:08Z
dc.date.available2018-03-28T22:05:08Z
dc.identifier
dc.identifierArchives Of Gynecology And Obstetrics. , v. 284, n. 6, p. 1523 - 1531, 2011.
dc.identifier9320067
dc.identifier10.1007/s00404-011-1886-x
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84862608098&partnerID=40&md5=b389611d9072013dc39c04ae72f11a37
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/108898
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/108898
dc.identifier2-s2.0-84862608098
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1254930
dc.descriptionPurpose: To evaluate quality of life (QOL) in gynecologic cancer survivors after radiotherapy (RT), investigate the frequency of adverse events and demonstrate an association between these symptoms and QOL. Methods: A prospective cohort study of 95 women aged 21-75 years undergoing RT for gynecologic cancer was carried out. QOL was assessed by the WHOQOL-BREF before, at 4 months, 1 year and 3 years after RT and adverse events were evaluated following RT by the (CTCAE) v 3.0 scale. QOL scores were assessed by the Wilcoxon signed rank test over time. Multiple linear regression analysis was used to identify predictors of QOL. Results: The most frequent adverse events were pain (64.2%) and dyspareunia (45.9%). A significant increase in QOL scores was observed in the psychological domain, general health and overall QOL. Pain was negatively associated with the physical, psychological and social relationship domains (p < 0.01); dyspareunia with the physical and social relationship (p < 0.01); decreased sexual interest with the psychological (p < 0.01). Higher family income was positively associated with the psychological domain and general health (p < 0.01). Conclusions: Results suggested that QOL improved after RT in women with gynecologic cancer. Adverse events, such as pain, dyspareunia and decreased sexual interest had a negative impact on QOL. © Springer-Verlag 2011.
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dc.languageen
dc.publisher
dc.relationArchives of Gynecology and Obstetrics
dc.rightsfechado
dc.sourceScopus
dc.titleQuality Of Life And Adverse Events After Radiotherapy In Gynecologic Cancer Survivors: A Cohort Study
dc.typeArtículos de revistas


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