Normalization Of Height And Excess Body Fat In Children With Salt-wasting 21-hydroxylase Deficiency [normalização Da Estatura E Excesso De Adiposidade Corporal Em Crianças Com A Forma Perdedora De Sal Da Deficiência Da 21-hidroxilase]

dc.creatorMendes-dos-Santos C.T.
dc.creatorDe Lemos-Marini S.H.V.
dc.creatorBaptista M.T.M.
dc.creatorGuerra Jr. G.
dc.creatorDe-Mello M.P.
dc.creatorPaulino M.F.V.M.
dc.creatorMorcillo A.M.
dc.date2011
dc.date2015-06-30T20:40:55Z
dc.date2015-11-26T14:53:06Z
dc.date2015-06-30T20:40:55Z
dc.date2015-11-26T14:53:06Z
dc.date.accessioned2018-03-28T22:05:04Z
dc.date.available2018-03-28T22:05:04Z
dc.identifier
dc.identifierJornal De Pediatria. , v. 87, n. 3, p. 263 - 268, 2011.
dc.identifier217557
dc.identifier10.2223/JPED.2095
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-79958714897&partnerID=40&md5=fa365a0bba8eb03bbb83ea0342365a6f
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/108870
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/108870
dc.identifier2-s2.0-79958714897
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1254920
dc.descriptionObjective: To evaluate growth and body composition of patients with the salt wasting form of classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency and to compare them with healthy children. Methods: Twenty-one prepubertal patients (eight boys and 13 girls) between 2.1 and 10.2 years and 67 prepubertal healthy controls (36 boys and 31 girls) between 1.2 and 11.7 years were included. Weight, height, upper-arm circumference, skinfolds, body composition determined by bioimpedance, and bone age were measured. The following data were obtained from the medical records: parents' height, serum levels of 17-hydroxyprogesterone and Δ4-androstenedione, prescribed hydrocortisone doses, weight and length at birth, in the beginning of the treatment, and at 2 years. Results: Patients had lower weight and length z scores at the first appointment compared with the same data at birth, showing recovery after the beginning of the treatment without advanced bone age. Mean height z score was higher in controls (0.28±0.86) than in patients (-0.61±0.99, p < 0.001); this difference disappeared when the patients' height was adjusted to their bone age (0.33±1.68, p = 0.912). Patients had higher body mass index (p < 0.001), fat mass (p < 0.001), and fat mass index (p < 0.001) than controls. There was no difference in the skinfolds between the two groups (p = 0.157). Conclusions: Patients had growth recovery with mean height similar to the general population; however, they had higher body fat, which seems to be visceral, since there was no difference between the skinfolds of both groups. Copyright © 2011 by Sociedade Brasileira de Pediatria.
dc.description87
dc.description3
dc.description263
dc.description268
dc.descriptionSpeiser, P.W., Azziz, R., Baskin, L.S., Ghizzoni, L., Hensle, T.W., Merke, D.P., Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: An Endocrine Society clinical practice guideline (2010) J Clin Endocrinol Metab, 95, pp. 4133-4160
dc.descriptionForest, M.G., Recent advances in the diagnosis and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency (2004) Human Reproduction Update, 10 (6), pp. 469-485. , DOI 10.1093/humupd/dmh047
dc.descriptionEugster, E.A., DiMeglio, L.A., Wright, J.C., Freidenberg, G.R., Seshadri, R., Pescovitz, O.H., Height outcome in congenital adrenal hyperplasia caused by 21-hydroxylase deficiency: A meta-analysis (2001) Journal of Pediatrics, 138 (1), pp. 26-32. , DOI 10.1067/mpd.2001.110527
dc.descriptionCameron, F.J., Kaymakci, B., Byrt, E.A., Ebeling, P.R., Warne, G.L., Walk, J.D., Bone mineral density and body composition in congenital adrenal hyperplasia (1995) J Clin Endocrinol Metab, 80, pp. 2238-2243
dc.descriptionCornean, R.E., Hindmarsh, P.C., Brook, C.G.D., Obesity in 21-hydroxylase deficient patients (1998) Archives of Disease in Childhood, 78 (3), pp. 261-263
dc.descriptionHagenfeldt, K., Martin Ritzén, E., Ringertz, H., Helleday, J., Carlström, K., Bone mass and body composition of adult women with congenital virilizing 21-hydroxylase deficiency after glucocorticoid treatment since infancy (2000) Eur J Endocrinol, 143, pp. 667-671
dc.descriptionManoli, I., Kanaka-Gantenbein, C.., Voutetakis, A., Maniati-Christidi, M., Dacou-Voutetakis, C., Early growth, pubertal development, body mass index and final height of patients with congenital adrenal hyperplasia: Factors influencing the outcome (2002) Clinical Endocrinology, 57 (5), pp. 669-676. , DOI 10.1046/j.1365-2265.2002.01645.x
dc.descriptionStikkelbroeck, N.M.M.L., Oyen, W.J.G., Van Der, W.G.-J., Hermus, A.R.M.M., Otten, B.J., Normal bone mineral density and lean body mass, but increased fat mass, in young adult patients with congenital adrenal hyperplasia (2003) Journal of Clinical Endocrinology and Metabolism, 88 (3), pp. 1036-1042. , DOI 10.1210/jc.2002-021074
dc.descriptionVölkl, T.M., Simm, D., Beier, C., Dörr, H.G., Obesity among children and adolescents with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (2006) Pediatrics, 117, pp. e98-e105
dc.descriptionMuthusamy, K., Elamin, M.B., Smushkin, G., Murad, M.H., Lampropulos, J.F., Elamin, K.B., Clinical review: Adult height in patients with congenital adrenal hyperplasia: A systematic review and metaanalysis (2010) J Clin Endocrinol Metab, 95, pp. 4161-4172
dc.descriptionHargitai, G., Sólyom, J., Battelino, T., Lebl, J., Pribilincová, Z., Hauspie, R., Growth patterns and final height in congenital adrenal hyperplasia due to classical 21-hydroxylase deficiency. Results of a multicenter study (2001) Horm Res, 55, pp. 161-171
dc.descriptionVan Der, K.H.J., Otten, B.J., Buitenweg, N., De Muinck K.-Schrama, S.M.P.F., Oostdijk, W., Jansen, M., Delemarre-de, W.H.A., Wit, J.M., Longitudinal analysis of growth and puberty in 21-hydroxylase deficiency patients (2002) Archives of Disease in Childhood, 87 (2), pp. 139-144. , DOI 10.1136/adc.87.2.139
dc.descriptionLemos-Marini, S.H., Guerra-Júnior, G., Morcillo, A.M., Baptista, M.T., Silva, L.O., Maciel-Guerra, A.T., Hiperplasia congênita das supra-renais por deficiência da 21-hidroxilase: Altura final de 27 pacientes com a forma clássica (2005) Arq Bras Endocrinol Metab, 49, pp. 902-907
dc.descriptionPaulino, L.C., Araujo, M., Guerra, G., Marini, S.H.V.L., De Mello, M.P., Mutation distribution and CYP21/C4 locus variability in Brazilian families with the classical form of the 21-hydroxylase deficiency (1999) Acta Paediatrica, International Journal of Paediatrics, 88 (3), pp. 275-283. , DOI 10.1080/08035259950170024
dc.descriptionSoardi, F.C., Barbaro, M., Lau, I.F., Lemos-Marini, S.H.V., Baptista, M.T.M., Guerra Jr., G., Wedell, A., De Mello, M.P., Inhibition of CYP21A2 enzyme activity caused by novel missense mutations identified in brazilian and scandinavian patients (2008) Journal of Clinical Endocrinology and Metabolism, 93 (6), pp. 2416-2420. , http://jcem.endojournals.org/cgi/reprint/93/6/2416, DOI 10.1210/jc.2007-2594
dc.descriptionFrisancho, A.R., Anthropometric standards (1993) Anthropometric Standards for the Assessment of Growth and Nutritional Status, pp. 37-118. , Frisancho AR. Michigan: The University of Michigan Press
dc.descriptionGoran, M.I., Kaskoun, M.C., Carpenter, W.H., Poehlman, E.T., Ravussin, E., Fontvieille, A.-M., Estimating body composition of young children by using bioelectrical resistance (1993) Journal of Applied Physiology, 75 (4), pp. 1776-1780
dc.descriptionTanner, J.M., Whitehouse, R.H., Cameron, N., Marshall, W.A., Healy, M.J., Goldstein, H., The rating system (1983) Assessment of Skeletal Maturity and Prediction of Adult Height (TW2 Method), pp. 50-103. , Tanner JM, Whitehouse RH, Cameron N, Marshall WA, Healy MJ, Goldstein H. 2nd ed. London: Academic Press
dc.descriptionTanner, J.M., Goldstein, H., Whitehouse, R.H., Standards for children's height at ages 2-9 years allowing for heights of parents (1970) Arch Dis Child, 45, pp. 755-762
dc.descriptionKuczmarski, R.J., Ogden, C.L., Grummer-Strawn, L.M., Flegal, K.M., Guo, S.S., Wei, R., CDC growth charts: United States (2000) Adv Data, pp. 1-27
dc.descriptionMarcondes, E., Curvas de crescimento e normalidade do crescimento (1994) Desenvolvimento Da Criança: Desenvolvimento Biológico, Crescimento, pp. 39-56. , Marcondes E. Rio de Janeiro: Sociedade Brasileira de Pediatria
dc.descriptionYu, A.C., Grant, D.B., Adult height in women with early-treated congenital adrenal hyperplasia (21-hydroxylase type): Relation to body mass index in earlier childhood (1995) Acta Paediatr, 84, pp. 899-903
dc.descriptionMendes-dos-Santos, C.T., Lemos-Marini, S.H., Baptista, M.T., Guerra-Junior, G., De-Mello, M.P., Morcillo, A.M., Crescimento de pacientes com hiperplasia congênita das supra-renais, forma perdedora de sal, nos primeiros dois anos de vida (2009) Rev Bras Saude Matern Infant, 9, pp. 415-421
dc.descriptionFernandes, R.A., Rosa, C.S.C., Buonani, C., De Oliveira, A.R., Freitas Jr., I.F., The use of bioelectrical impedance to detect excess visceral and subcutaneous fat (2007) Jornal de Pediatria, 83 (6), pp. 529-534. , http://www.jped.com.br/conteudo/07-83-06-529/ing.pdf, DOI 10.2223/JPED.1722
dc.descriptionLinder, B.L., Esteban, N.V., Yergey, A.L., Winterer, J.C., Loriaux, D.L., Cassorla, F., Cortisol production rate in childhood and adolescence (1990) J Pediatr, 117, pp. 892-896
dc.descriptionIsguven, P., Arslanoglu, I., Mesutoglu, N., Yildiz, M., Erguven, M., Bioelectrical impedance analysis of body fatness in childhood congenital adrenal hyperplasia and its metabolic correlates (2008) Eur J Pediatr, 167, pp. 1263-1268
dc.descriptionWajchenberg, B.L., Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome (2000) Endocrine Reviews, 21 (6), pp. 697-738. , DOI 10.1210/er.21.6.697
dc.descriptionFraser, R., Ingram, M.C., Anderson, N.H., Morrison, C., Davies, E., Connell, J.M.C., Cortisol effects on body mass, blood pressure, and cholesterol in the general population (1999) Hypertension, 33 (6), pp. 1364-1368
dc.descriptionGoran, M.I., Gower, B.A., Relation between visceral fat and disease risk in children and adolescents (1999) Am J Clin Nutr, 70, pp. 149S-56S
dc.descriptionHamdy, O., Porramatikul, S., Al-Ozairi, E., Metabolic obesity: The paradox between visceral and subcutaneous fat (2006) Current Diabetes Reviews, 2 (4), pp. 367-373. , http://www.ingentaconnect.com/content/ben/cdr/2006/00000002/00000004/ art00001
dc.descriptionMadeira, I.R., Carvalho, C.N., Gazolla, F.M., Pinto, L.W., Borges, M.A., Bordallo, M.A., Impact of obesity on metabolic syndrome components and adipokines in prepubertal children (2009) J Pediatr, 85, pp. 261-268. , Rio J
dc.languagept
dc.publisher
dc.relationJornal de Pediatria
dc.rightsaberto
dc.sourceScopus
dc.titleNormalization Of Height And Excess Body Fat In Children With Salt-wasting 21-hydroxylase Deficiency [normalização Da Estatura E Excesso De Adiposidade Corporal Em Crianças Com A Forma Perdedora De Sal Da Deficiência Da 21-hidroxilase]
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución