| dc.creator | Matsumura C.Y. | |
| dc.creator | Taniguti A.P.T. | |
| dc.creator | Pertille A. | |
| dc.creator | Neto H.S. | |
| dc.creator | Marques M.J. | |
| dc.date | 2011 | |
| dc.date | 2015-06-30T20:38:58Z | |
| dc.date | 2015-11-26T14:52:44Z | |
| dc.date | 2015-06-30T20:38:58Z | |
| dc.date | 2015-11-26T14:52:44Z | |
| dc.date.accessioned | 2018-03-28T22:04:46Z | |
| dc.date.available | 2018-03-28T22:04:46Z | |
| dc.identifier | | |
| dc.identifier | American Journal Of Physiology - Cell Physiology. , v. 301, n. 6, p. C1344 - C1350, 2011. | |
| dc.identifier | 3636143 | |
| dc.identifier | 10.1152/ajpcell.00056.2011 | |
| dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-82455219484&partnerID=40&md5=9e052692aa0579412761725819eb8f5d | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/108785 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/108785 | |
| dc.identifier | 2-s2.0-82455219484 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1254862 | |
| dc.description | In Duchenne muscular dystrophy (DMD) and in the mdx mouse model of DMD, the lack of dystrophin is related to enhanced calcium influx and muscle degeneration. Stretch-activated channels (SACs) might be directly involved in the pathology of DMD, and transient receptor potential cation channels have been proposed as likely candidates of SACs. We investigated the levels of transient receptor potential canonical channel 1 (TRPC1) and the effects of streptomycin, a SAC blocker, in muscles showing different degrees of the dystrophic phenotype. Mdx mice (18 days old, n = 16) received daily intraperitoneal injections of streptomycin (182 mg/kg body wt) for 18 days, followed by removal of the diaphragm, sternomastoid (STN), biceps brachii, and tibialis anterior muscles. Control mdx mice (n = 37) were injected with saline. Western blot analysis showed higher levels of TRPC1 in diaphragm muscle compared with STN and limb muscles. Streptomycin reduced creatine kinase and prevented exercise-induced increases of total calcium and Evans blue dye uptake in diaphragm and in STN muscles. It is suggested that different levels of the stretch-activated calcium channel protein TRPC1 may contribute to the different degrees of the dystrophic phenotype seen in mdx mice. Early treatment designed to regulate the activity of these channels may ameliorate the progression of dystrophy in the most affected muscle, the diaphragm. © 2011 the American Physiological Society. | |
| dc.description | 301 | |
| dc.description | 6 | |
| dc.description | C1344 | |
| dc.description | C1350 | |
| dc.description | Allen, D.G., Whitehead, N.P., Yeung, E.W., Mechanisms of stretch-induced muscle damage in normal and dystrophic muscle: Role of ionic changes (2005) J Physiol, 567 (723), p. 735 | |
| dc.description | Barton-Davis, E.R., Cordier, L., Shoturma, D.I., Leland, S.E., Sweeney, H.L., Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice (1999) J Clin Invest, 104 (375), p. 381 | |
| dc.description | Beech, D.J., TRPC1: Store-operated channel and more (2005) Pflügers Arch, 451 (53), p. 60 | |
| dc.description | Bertorini, T.E., Palmieri, G.M., Griffin, J.W., Igarashi, M., McGee, J., Brown, R., Nutting, D.F., Karas, J.G., Effect of chronic treatment with the calcium antagonist diltiazem in Duchenne muscular dystrophy (1988) Neurology, 38 (609), p. 613 | |
| dc.description | Bulfield, G., Siller, W.G., Wight, P.A.L., Moore, K.J., X chromosome-linked muscular dystrophy (mdx) in the mouse (1984) Proc Natl Acad Sci USA, 81, pp. 1189+1192 | |
| dc.description | Burdi, R., Rolland, J.F., Fraysse, B., Litvinova, K., Cozzoli, A., Giannuzzi, V., Liantonio, A., de Luca, A., Multiple pathological events in exercised dystrophic mdx mice are targeted by pentoxifylline: Outcome of a large array of in vivo and ex vivo tests (2009) J Appl Physiol, 106 (1311), p. 1324 | |
| dc.description | Burkholder, T.J., Fingado, B., Baron, S., Lieber, R.L., Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb (1994) J Morphol, 221 (177), p. 190 | |
| dc.description | Engel, A.G., Yamamoto, M., Fischbeck, K.H., (1994) Dystrophinopathies:In Myology, , edited by Engel AG, Franzini-Armstrong. New York: McGraw- Hill | |
| dc.description | Ervasti, J.M., Dystrophin, its interactions with other proteins, and implications for muscular dystrophy (2007) Biochim Biophys Acta, 1772 (108), p. 117 | |
| dc.description | Ferretti, R., Marques, M.J., Pertille, A., Neto, H.S., Sarcoplasmicendoplasmic- reticulum calcium Ca 2+-ATPase and calsequestrin are overexpressed in spared intrinsic laryngeal muscles of dystrophin-deficient mdx mice (2009) Muscle Nerve, 39 (609), p. 615 | |
| dc.description | Fong, P., Turner, P.R., Denetclaw, W.F., Steinhardt, R.A., Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin (1990) Science, 250 (673), p. 676 | |
| dc.description | Franco Jr., A., Lansman, J.B., Calcium entry through stretch-inactivated ion channels in mdx myotubes (1990) Nature, 344 (670), p. 673 | |
| dc.description | Franco Jr., A., Lansman, J.B., Stretch-sensitive channels in developing muscle cells from a mouse cell line (1990) J Physiol, 427 (361), p. 380 | |
| dc.description | Franco-Obregón Jr., A., Lansman, J.B., Mechanosensitive ion channels in skeletal muscle from normal and dystrophic mice (1994) J Physiol, 481, pp. 299-309 | |
| dc.description | Franco-Obregón, A., Lansman, J.B., Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse (2002) J Physiol, 539 (391), p. 407 | |
| dc.description | Gervásio, O.L., Whitehead, N.P., Yeung, E.W., Phillips, W.D., Allen, D.G., TRPC1 binds to caveolin-3 and is regulated by Src kinase-role in Duchenne muscular dystrophy (2008) J Cell Sci, 121 (2246), p. 2255 | |
| dc.description | Gottlieb, P., Folgering, J., Maroto, R., Raso, A., Wood, T.G., Kurosky, A., Bowman, C., Honoré, E., Revisiting TRPC1 and TRPC6 mechanosensitivity (2008) Pflügers Arch, 455 (1097), p. 1103 | |
| dc.description | Grounds, M.D., Radley, H.G., Lynch, G.S., Nagaraju, K., de Luca, A., Towards developing standard operating procedures for preclinical testing in the mdx mouse model of Duchenne muscular dystrophy (2008) Neurobiol Dis, 31 (1), p. 19 | |
| dc.description | Guharay, F., Sachs, F., Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle (1984) J Physiol, 352 (685), p. 701 | |
| dc.description | Jorgensen, L.H., Blain, A., Greally, E., Laval, S.H., Blamire, A.M., Davison, B.J., Brinkmeier, H., Lochmüller, H., Long-term blocking of calcium channels in mdx mice results in differential effects on heart and skeletal muscle (2011) Am J Pathol, 178 (273), p. 283 | |
| dc.description | Lefaucheur, J.P., Pastoret, C., Sebille, A., Phenotype of dystrophinopathy in old mdx mice (1995) Anat Rec, 242 (70), p. 76 | |
| dc.description | Mallouk, N., Jacquemond, V., Allard, B., Elevated subsarcolemmal Ca 2+ in mdx mouse skeletal muscle fibers detected with Ca 2+-activated K 2+ channels (2000) Proc Natl Acad Sci USA, 97 (4950), p. 4955 | |
| dc.description | Maroto, R., Raso, A., Wood, T.G., Kurosky, A., Martinac, B., Hamill, O.P., TRPC1 forms the stretch-activated cation channel in vertebrate cells (2005) Nat Cell Biol, 7 (179), p. 185 | |
| dc.description | Marques, M.J., Matsumura, C.Y., Neto, H.S., Alterations in the permeability of dystrophic fibers during neuromuscular junction development (2007) Acta Biol Hung, 58 (1), p. 9 | |
| dc.description | Matsumura, C.Y., Albuquerque, T.C.P., Pertille, A., Neto, H.S., Marques, M.J., Diltiazem and verapamil protect dystrophin-deficient muscle fibers of mdx mice from degeneration: A potential role in calcium buffering and sarcolemmal stability (2009) Muscle Nerve, 39 (167), p. 176 | |
| dc.description | Patel, A., Sharif-Naeini, R., Folgering, J.R.H., Bichet, D., Duprat, F., Honoré, Canonical TRP channels and mechanotransduction: From physiology to disease states (2010) Pflügers Arch, 460 (571), p. 581 | |
| dc.description | Pertille, A., Carvalho, C.L.T., Matsumura, C.Y., Neto, H.S., Marques, M.J., Calcium-binding proteins in skeletal muscles of the mdx mice: Potential role in the pathogenesis of Duchenne muscular dystrophy (2010) Int J Exp Pathol, 91 (63), p. 71 | |
| dc.description | Quinlan, J.G., Hahn, H.S., Wong, B.L., Lorenz, J.N., Wenisch, A.S., Levin, L.S., Evolution of the mdx mouse cardiomyopathy: Physiological and morphological findings (2004) Neuromuscul Disord, 14 (491), p. 496 | |
| dc.description | Robert, V., Massimino, M.L., Tosello, V., Marsault, R., Cantini, M., Sorrentino, V., Pozzan, T., Alterations in calcium handling at the subcellular level in mdx myotubes (2001) J Biol Chem, 276 (4647), p. 4651 | |
| dc.description | Sabourin, J., Lamiche, C., Vandebrouck, A., Magaud, C., Rivet, J., Cognard, C., Bourmeyster, N., Constantin, B., Regulation of TRPC1 and TRPC4 cation channels requires an 1-syntrophin-dependent complex in skeletal mouse myotubes (2009) J Biol Chem, 284, p. 36261. , 36248 | |
| dc.description | Spassova, M.A., Hewavitharana, T., Xu, W., Soboloff, J., Gill, D.L., A common mechanism underlies stretch activation and receptor activation of TRPC6 channels (2006) Proc Natl Acad Sci USA, 103, p. 16591. , 16586 | |
| dc.description | Spurney, C.F., Knoblach, S., Pistilli, E.E., Nagaraju, K., Martin, G.R., Hoffman, E.P., Dystrophin deficient cardiomyopathy in mouse: Expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart (2008) Neuromuscul Disord, 18 (371), p. 381 | |
| dc.description | Stedman, H.H., Sweeny, H.L., Shrager, J.B., Maguire, H.C., Panettieri, R.A., Petrof, B., Narusawa, M., Kelly, A.M., The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy (1991) Nature, 352 (536), p. 538 | |
| dc.description | Turner, P.R., Fong, P., Denetclaw, W.F., Steinhardt, R.A., Increased calcium influx in dystrophic muscle (1991) J Cell Biol, 115 (1701), p. 1712 | |
| dc.description | Vandebrouck, C., Duport, G., Cognard, C., Raymond, G., Cationic channels in normal and dystrophic human myotubes (2001) Neuromuscul Disord, 11 (72), p. 79 | |
| dc.description | Vandebrouck, C., Martin, D., Colson-Van Schoor, M., Debaix, H., Gailly, P., Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers (2002) J Cell Biol, 158, pp. 1089-1096 | |
| dc.description | Vandebrouck, A., Sabourin, J., Rivet, J., Balghi, H., Sebille, S., Kitzis, A., Raymond, G., Constantin, B., Regulation of capacitative calcium entries by 1-syntrophin: Association of TRPC1 with dystrophin complex and the PDZ domain of 1-syntrophin (2007) FASEB J, 21 (608), p. 617 | |
| dc.description | Villalta, S.A., Nguyen, H.X., Deng, B., Gotoh, T., Tidball, J.G., Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy (2009) Hum Mol Genet, 18 (482), p. 496 | |
| dc.description | Ward, M.L., Williams, I.A., Chu, Y., Cooper, P.J., Ju, Y.K., Allen, D.G., Stretch-activated channels in the heart: Contributions to length-dependence and to cardiomyopathy (2008) Prog Biophys Mol Biol, 97 (232), p. 249 | |
| dc.description | Whitehead, N.P., Streamer, M., Lusambili, L.I., Sachs, F., Allen, D.G., Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice (2006) Neuromuscul Disord, 16 (845), p. 854 | |
| dc.description | Whitehead, N.P., Yeung, E.W., Allen, D.G., Muscle damage in mdx (dystrophic) mice: Role of calcium and reactive oxygen species (2006) Clin Exp Pharmacol Physiol, 33 (657), p. 662 | |
| dc.description | Williams, I.A., Allen, D.G., Intracellular calcium handling in ventricular myocytes from mdx mice (2007) Am J Physiol Heart Circ Physiol, 292, pp. H846-H855 | |
| dc.description | Yeung, E.W., Allen, D.G., Stretch-activated channels in stretch-induced muscle damage: Role in muscular dystrophy (2004) Clin Exp Pharmacol Physiol, 31 (551), p. 556 | |
| dc.description | Yeung, E.W., Whitehead, N.P., Suchyna, T.M., Gottlieb, P.A., Sachs, F., Allen, D.G., Effects of stretch-activated channel blockers on [Ca 2+]i and muscle damage in the mdx mouse (2005) J Physiol, 562 (367), p. 380 | |
| dc.description | Yoshida, M., Yonetani, A., Shirasaki, T., Wada, K., Dietary NaCl supplementation prevents muscle necrosis in a mouse model of Duchenne muscular dystrophy (2006) Am J Physiol Regul Integr Comp Physiol, 290, pp. R449-R455 | |
| dc.description | Zand, N., Chowdhry, B.Z., Zotor, F.B., Wray, D.S., Amuna, P., Pullen, F.S., Essential and trace elements content of commercial infant foods in the UK (2011) Food Chem, 128 (123), p. 128 | |
| dc.description | Zanou, N., Iwata, Y., Schakman, O., Lebacq, J., Wakabayashi, S., Gailly, P., Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions (2009) FEBS Lett, 583 (3600), p. 3604 | |
| dc.description | Zanou, N., Shapovalov, G., Louis, M., Tajeddine, N., Gallo, C., van Schoor, M., Anguish, I., Gailly, P., Role of TRCP1 channel in skeletal muscle function (2010) Am J Physiol Cell Physiol, 298, pp. C149-C162 | |
| dc.language | en | |
| dc.publisher | | |
| dc.relation | American Journal of Physiology - Cell Physiology | |
| dc.rights | fechado | |
| dc.source | Scopus | |
| dc.title | Stretch-activated Calcium Channel Protein Trpc1 Is Correlated With The Different Degrees Of The Dystrophic Phenotype In Mdx Mice | |
| dc.type | Artículos de revistas | |
