The interventricular septum is the most densely vascularized portion of the heart, containing important elements of the cardiac conduction system and providing mechanical support for both right and left ventricular function. The diagnosis and understanding of anomalies in coronary circulation are important when surgical or percutaneous myocardial revas-cularization is required. We report the case of a patient with an anomalous septal perforator artery arising from the proximal portion of the right coronary artery.191 Topaz, O., Vetrovec, G.W., Anomalous first septal perforator artery: Anatomic-clinical correlates (1996) Clin Anat, 9 (1), pp. 14-18James, T.N., Burch, G.E., Blood supply of the human interventricular septum (1958) Circulation, 17 (3), pp. 391-396Yamanaka, O., Hobbs, R.E., Coronary artery anomalies in 126,595 patients undergoing coronary arteriography (1990) Cathet Cardiovasc Diagn, 21 (1), pp. 28-40Tuncer, C., Batyraliev, T., Yilmaz, R., Gokce, M., Eryonucu, B., Koroglu, S., Origin and distribution anomalies of the left anterior descending artery in 70,850 adult patients: Multicenter data collection (2006) Catheter Cardiovasc Interv, 68 (4), pp. 574-585Tüccar, E., Elhan, A., Examination of coronary artery anomalies in an adult Turkish population (2002) Turk J Med Sci, 32, pp. 309-312Cheng, T.O., Prevalence and relevance of coronary artery anomalies (1997) Cathet Cardiovasc Diagn, 42 (3), pp. 276-277Bream, P.R., Jones, J.M., Elliott, L.P., The anomalous septal perforating artery. Its origin from the first diagonal, first marginal, or circumflex artery (1981) Radiology, 138 (2), pp. 301-307Stoney, W.S., Vernon, R.P., Alford Jr., W.C., Burrus, G.R., Thomas Jr., C.S., Revascularization of the septal artery (1976) Ann Thorac Surg, 21 (1), pp. 2-6Topaz, O., Mackall, J.A., Nair, R., Thames, M.D., Hodgson, J.M., Anomalous septal perforator artery: A source for supportive circulation in severe coronary artery disease-case reports (1992) An-giology, 43 (6), pp. 501-505Palomo, A.R., Schrager, B.R., Chahine, R.A., Anomalous separate origin of the septal perforator coronary artery from the left sinus of Valsalva (1984) Cathet Cardiovasc Diagn, 10 (4), pp. 385-388Bream, P.R., Souza Jr., A.S., Elliott, L.P., Soto, B., Curry, G.C., Right superior septal perforator artery: Its angiographic description and clinical significance (1979) AJR Am J Roentgenol, 133 (1), pp. 67-73Choi, D., Dardano, J., Naidu, S.S., Alcohol septal ablation through an anomalous right coronary septal perforator: First report and discussion (2009) J Invasive Cardiol, 21 (6), pp. e106-9