Tracheal Occlusion For Fetuses With Severe Isolated Left-sided Diaphragmatic Hernia: A Nonrandomized Controlled Experimental Study [oclusão Traqueal Para Fetos Com Hérnia Diafragmática Esquerda Grave Isolada: Um Estudo Experimental Controlado Não Randomizado]

dc.creatorPeralta C.F.A.
dc.creatorSbragia L.
dc.creatorBennini J.R.
dc.creatorCavalli R.C.
dc.creatorRousselet M.S.
dc.creatorBarini R.
dc.date2011
dc.date2015-06-30T20:33:46Z
dc.date2015-11-26T14:51:11Z
dc.date2015-06-30T20:33:46Z
dc.date2015-11-26T14:51:11Z
dc.date.accessioned2018-03-28T22:02:43Z
dc.date.available2018-03-28T22:02:43Z
dc.identifier
dc.identifierRevista Brasileira De Ginecologia E Obstetricia. , v. 33, n. 12, p. 381 - 387, 2011.
dc.identifier1007203
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84856619653&partnerID=40&md5=398d13bb370fe317f64afaf567a2d81c
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/108409
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/108409
dc.identifier2-s2.0-84856619653
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1254413
dc.descriptionPURPOSE: To compare postnatal survival to hospital discharge of fetuses with severe isolated left-sided congenital diaphragmatic hernia, who underwent tracheal occlusion, with that of nonrandomized contemporaneous controls. METHODS: Experimental nonrandomized controlled study, performed from April 2007 to September 2011. Fetuses with severe isolated left-sided congenital diaphragmatic hernia with liver herniation into the chest and lung area-to-head circumference ratio <1.0, who underwent tracheal occlusion (study group) or expectant management (non-randomized contemporaneous controls), were compared in terms of lung area-to-head circumference ratio and observed/expected lung area-to-head circumference ratio (observed/expected lung area-to-head circumference ratio) at the time of diagnosis, gestational age at birth, and survival to hospital discharge. Modifications in lung area-to-head circumference ratio and o/e lung area-to-head circumference ratio after tracheal occlusion were also analyzed. Fisher's exact test, Mann-Whitney's or Wilcoxon's tests were used for the comparisons. RESULTS: There were no significant differences between the Study Group (TO=28) and Controls (n=13) in terms of the lung area-to-head circumference ratio (p=0.709) and the observed/expected lung area-to-head circumference ratio (p=0.5) at the time of diagnosis and gestational age at birth (p=0.146). The survival to hospital discharge was higher (p=0.012) in the tracheal occlusion group (10/28=35.7%) than in controls (0/13=0.0%). There was a significant increase in lung area-to-head circumference ratio (p<0.001) and observed/expected lung area-to-head circumference ratio (p<0.001) between the diagnosis of the congenital diaphragmatic hernia [lung area-to-head circumference ratio: 0.80 (0.40-0.94); observed/expected lung area-to-head circumference ratio: 27.0 (15.3-45.0)], and the day before retrieval of the balloon [lung area-to-head circumference ratio: 1.2 (0.50-1.80); observed/expected lung area-to-head circumference ratio: 40.0 (17.5-60.0)]. CONCLUSIONS: There was a significant improvement in the survival rate to hospital discharge of fetuses with severe isolated left-sided congenital diaphragmatic hernia, who underwent tracheal occlusion in comparison to nonrandomized contemporaneous controls.
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dc.description381
dc.description387
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dc.languageen
dc.languagept
dc.publisher
dc.relationRevista Brasileira de Ginecologia e Obstetricia
dc.rightsaberto
dc.sourceScopus
dc.titleTracheal Occlusion For Fetuses With Severe Isolated Left-sided Diaphragmatic Hernia: A Nonrandomized Controlled Experimental Study [oclusão Traqueal Para Fetos Com Hérnia Diafragmática Esquerda Grave Isolada: Um Estudo Experimental Controlado Não Randomizado]
dc.typeArtículos de revistas


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