Effects Of The Topical Application Of Hydroalcoholic Leaf Extract Of Oncidium Flexuosum Sims. (orchidaceae) And Microcurrent On The Healing Of Wounds Surgically Induced In Wistar Rats

dc.creatorDe Gaspi F.O.D.G.
dc.creatorFoglio M.A.
dc.creatorDe Carvalho J.E.
dc.creatorSantos G.M.T.
dc.creatorTesta M.
dc.creatorPassarini Jr. J.R.
dc.creatorDe Moraes C.P.
dc.creatorEsquisatto M.A.M.
dc.creatorMendonca J.S.
dc.creatorMendonca F.A.S.
dc.date2011
dc.date2015-06-30T20:27:30Z
dc.date2015-11-26T14:49:48Z
dc.date2015-06-30T20:27:30Z
dc.date2015-11-26T14:49:48Z
dc.date.accessioned2018-03-28T22:00:53Z
dc.date.available2018-03-28T22:00:53Z
dc.identifier
dc.identifierEvidence-based Complementary And Alternative Medicine. , v. 2011, n. , p. - , 2011.
dc.identifier1741427X
dc.identifier10.1155/2011/950347
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-80052692602&partnerID=40&md5=fc6d8d1c4d302ab598af8d2908767cbc
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/108014
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/108014
dc.identifier2-s2.0-80052692602
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1254008
dc.descriptionThis study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 μA/2min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (P<.05), with positive effects on the area of newly formed tissue, number of fibroblasts, number of newly formed blood vessels, and epithelial thickness. Morphometric data confirmed the structural findings. The O. flexuosum leaf extract contains active compounds that speed the healing process, especially when applied simultaneously with microcurrent stimulation. Copyright © 2011 Fernanda Oliveira de G. de Gaspi et al.
dc.description2011
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dc.languageen
dc.publisher
dc.relationEvidence-based Complementary and Alternative Medicine
dc.rightsaberto
dc.sourceScopus
dc.titleEffects Of The Topical Application Of Hydroalcoholic Leaf Extract Of Oncidium Flexuosum Sims. (orchidaceae) And Microcurrent On The Healing Of Wounds Surgically Induced In Wistar Rats
dc.typeArtículos de revistas


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