dc.creator | Arruda P. | |
dc.creator | Kemper E.L. | |
dc.creator | Papes F. | |
dc.creator | Leite A. | |
dc.date | 2000 | |
dc.date | 2015-06-30T19:50:35Z | |
dc.date | 2015-11-26T14:47:09Z | |
dc.date | 2015-06-30T19:50:35Z | |
dc.date | 2015-11-26T14:47:09Z | |
dc.date.accessioned | 2018-03-28T21:57:21Z | |
dc.date.available | 2018-03-28T21:57:21Z | |
dc.identifier | | |
dc.identifier | Trends In Plant Science. , v. 5, n. 8, p. 324 - 330, 2000. | |
dc.identifier | 13601385 | |
dc.identifier | 10.1016/S1360-1385(00)01688-5 | |
dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-0034254531&partnerID=40&md5=a40b5f3e2df4e45e126797cdab600606 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/107229 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/107229 | |
dc.identifier | 2-s2.0-0034254531 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1253152 | |
dc.description | Lysine is an essential amino acid for mammals but its concentration in cereals, one of our main food sources, is low. Research over the past 40 years has unraveled many biochemical and molecular details of the aspartic acid pathway, which is the main route of lysine biosynthesis in plants. However, genetic manipulation of this pathway has not been successful at producing high-lysine seeds. This is because lysine, instead of being accumulated, is degraded via the saccharopine pathway. Recent work has increased our knowledge of this pathway, including both the enzymes involved and their regulation. | |
dc.description | 5 | |
dc.description | 8 | |
dc.description | 324 | |
dc.description | 330 | |
dc.description | Azevedo, R.A., The biosynthesis and metabolism of the aspartate derived amino acids in higher plants (1999) Phytochemistry, 46, pp. 395-419 | |
dc.description | Galili, G., Regulation of lysine and threonine synthesis (1995) Plant Cell, 7, pp. 899-906 | |
dc.description | Shaul, O., Galili, G., Concerted regulation of lysine and threonine synthesis in tobacco plants expressing bacterial feedback-insensitive aspartate kinase and dihydrodipicolinate synthase (1993) Plant Mol. Biol., 23, pp. 759-768 | |
dc.description | Falco, S.C., Transgenic canola and soybean seeds with increased lysine (1995) Biotechnology, 13, pp. 577-582 | |
dc.description | Sodek, L., Biosynthesis of lysine and other amino acids in the developing maize endosperm (1976) Phytochemistry, 15, pp. 1903-1906 | |
dc.description | Arruda, P., Silva, W., Amino acid composition of vascular sap of maize ear peduncle (1979) Phytochemistry, 18, pp. 409-410 | |
dc.description | Shewry, P.R., Casey, R., Seed proteins (1999) Seed Proteins, pp. 1-10. , Casey, R. and Shewry, P.R., eds, Kluwer Academic Publishers | |
dc.description | Arruda, P., Lysine-ketoglutaric acid reductase activity in developing maize endosperm (1982) Plant Physiol., 69, pp. 988-989 | |
dc.description | Gaziola, S.A., The enzymology of lysine catabolism in rice seeds - isolation, characterization, and regulatory properties of a lysine 2-oxoglutarate reductase/saccharopine dehydrogenase bifunctional polypeptide (1997) Eur. J. Biochem., 247, pp. 364-371 | |
dc.description | Sodek, L., Wilson, C.M., Incorporation of leucine-C14 and lysine-C14 into protein in the developing endosperm of normal and opaque2 corn (1970) Arch. Biochem. Biophys., 140, pp. 29-38 | |
dc.description | Brandt, A.B., In vivo incorporation of lysine-C14 into the endosperm of wild type and high lysine barley (1975) FEBS Lett., 52, pp. 288-291 | |
dc.description | Gonçalves-Butruille, M., Purification and characterization of the bifunctional enzyme lysine-ketoglutarate reductase-saccharopine dehydrogenase from maize (1996) Plant Physiol., 110, pp. 765-771 | |
dc.description | Shewry, P.R., Tatham, A., The characteristcs, structures and evolutionary relationships of prolamins (1999) Seed Proteins, pp. 11-33. , Casey, R. and Shewry, P.R., eds, Kluwer Academic Publishers | |
dc.description | Arruda, P., Silva, W.J., Lysine-ketoglutaric acid reductase activity in maize: Its possible role on lysine metabolism of developing endosperm (1983) Phytochemistry, 22, pp. 206-208 | |
dc.description | Tang, G., Regulation of lysine catabolism through lysine-ketoglutaric acid reductase and saccharopine dehydrogenase in Arabidopsis (1997) Plant Cell, 9, pp. 1305-1316 | |
dc.description | Karchi, H., Lysine synthesis and catabolism are coordinately regulated during tobacco seed development (1994) Proc. Natl. Acad. Sci. U. S. A., 91, pp. 2577-2581 | |
dc.description | Miron, D., In vitro dephosphorylation inhibits the activity of soybean lysine-ketoglutaric acid reductase in a lysine-regulated manner (1997) Plant J., 12, pp. 1453-1458 | |
dc.description | Kemper, E.L., The role of Opaque2 on the control of lysine degrading activities in developing maize endosperm (1999) Plant Cell, 11, pp. 1981-1994 | |
dc.description | Schmidt, R.J., Opaque2 is a transcriptional activator that recognizes a specific target site in 22-kD zein genes (1992) Plant Cell, 4, pp. 689-700 | |
dc.description | Cord Neto, G., The involvement of Opaque2 on β-prolamin gene regulation in maize and Coix suggests a more general role for this transcriptional activator (1995) Plant Mol. Biol., 27, pp. 1015-1029 | |
dc.description | Brochetto-Braga, M.R., Partial purification and characterization of lysine-ketoglutarate reductase activity in normal and opaque2 maize endosperms (1992) Plant Physiol., 98, pp. 1139-1147 | |
dc.description | Gaziola, S.A., Quality protein maize: A biochemical study of enzymes involved in lysine metabolism (1999) J. Agric. Food Chem., 47, pp. 1268-1275 | |
dc.description | Azevedo, R.A., Biochemical genetics of the interaction of the lysine plus threonine resistant mutant Ltr*1 with opaque-2 maize mutant (1990) Plant Sci., 70, pp. 81-90 | |
dc.description | Karchi, H., The lysine-dependent stimulation of lysine catabolism in tobacco seed requires calcium and protein-phosphorylation (1995) Plant Cell, 7, pp. 1963-1970 | |
dc.description | Kemper, E.L., Structure and regulation of the bifunctional enzyme lysine-oxoglutarate reductase-saccharopine dehydrogenase in maize (1998) Eur. J. Biochem., 253, pp. 720-729 | |
dc.description | Epelbaum, S., Lysine-ketoglutaric acid reductase and saccharopine dehydrogenase from Arabidopsis thaliana: Nucleotide sequence and characterization (1997) Plant Mol. Biol., 35, pp. 735-748 | |
dc.description | Mazur, B., Gene discovery and product development for grain quality traits (1999) Science, 285, pp. 372-375 | |
dc.description | Ramos, F., Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae: Evidence for a regulatory route of LYS14 (1988) Eur. J. Biochem., 171, pp. 171-176 | |
dc.description | Hinnebusch, A.G., Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae (1988) Microbiol. Rev., 52, pp. 248-273 | |
dc.description | Müller, M., Knudsen, S., The nitrogen response of a barley C-hordein promoter is controlled by positive and negative regulation of the GCN4 and endosperm box (1993) Plant J., 4, pp. 343-355 | |
dc.description | Rao, V.V., Developmental changes of L-lysine-ketoglutaric acid reductase in rat brain and liver (1992) Comp. Biochem. Physiol. B Biochem. Mol. Biol., 103, pp. 221-224 | |
dc.description | Markovitz, P.J., Familial hyperlysinemias (1984) J. Biol. Chem., 259, pp. 11643-11646 | |
dc.description | Deleu, C., Three new osmotic stress-regulated cDNAs identified by differential display polymerase chain reaction in rapeseed leaf discs (1999) Plant Cell Environ., 22, pp. 979-988 | |
dc.description | Feller, A., Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation (1994) Mol. Cell. Biol., 14, pp. 6411-6418 | |
dc.description | Verhage, M., Synaptic assembly of the brain in the absence of neurotransmitter secretion (2000) Science, 287, pp. 864-869 | |
dc.description | Lam, H.M., Glutamic acid receptor genes in plants (1998) Nature, 396, pp. 125-126 | |
dc.description | Nanjo, T., Biological functions of proline in morphogenesis and osmotolerance revealed in antisense transgenic Arabidopsis thaliana (1999) Plant J., 18, pp. 185-193 | |
dc.language | en | |
dc.publisher | | |
dc.relation | Trends in Plant Science | |
dc.rights | fechado | |
dc.source | Scopus | |
dc.title | Regulation Of Lysine Catabolism In Higher Plants | |
dc.type | Artículos de revistas | |