Serum Levels Of Retinol Binding Protein 4 In Women With Different Levels Of Adiposity And Glucose Tolerance [níveis Séricos Da Proteína Carreadora Do Retinol 4 Em Mulheres Com Diferentes Níveis De Adiposidade E Tolerância à Glicose]

dc.creatorComucci E.B.
dc.creatorVasques A.C.J.
dc.creatorGeloneze B.
dc.creatorCalixto A.R.
dc.creatorPareja J.C.
dc.creatorTambascia M.A.
dc.date2014
dc.date2015-06-25T17:56:47Z
dc.date2015-11-26T14:47:02Z
dc.date2015-06-25T17:56:47Z
dc.date2015-11-26T14:47:02Z
dc.date.accessioned2018-03-28T21:57:11Z
dc.date.available2018-03-28T21:57:11Z
dc.identifier
dc.identifierArquivos Brasileiros De Endocrinologia E Metabologia. Sociedade Brasileira De Endocrinologia E Metabologia, v. 58, n. 7, p. 709 - 714, 2014.
dc.identifier42730
dc.identifier10.1590/0004-2730000002431
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84908370174&partnerID=40&md5=1bb4c2e2aa6854dd4acca8853a220c74
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/87118
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/87118
dc.identifier2-s2.0-84908370174
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1253105
dc.descriptionObjective: Retinol-binding protein 4 (RBP4) is an adipokine responsible for vitamin A (retinol) transportation. Studies associated RBP4 increased levels with severity of type 2 diabetes mellitus (T2DM) and insulin resistance (IR). The study aimed to quantify RBP4 serum standards in women with a wide range of body mass index (BMI) and glucose tolerance level. Subjects and methods: Cross-sectional study was performed with 139 women divided into three groups: Group 1 (lean-control, n = 45) and Group 2 (obese, n = 53) with normal glucose tolerance and group 3 (obese with T2DM, n = 41), called G1, G2 and G3. Were assessed clinical, biochemical, anthropometric and body composition parameters. Results: According to data analysis, we obtained in G1 higher RBP4 levels (104.8 ± 76.8 ng/mL) when compared to G2 (87.9 ± 38 ng/mL) and G3 (72.2 ± 15.6 ng/mL) levels. Also, were found: in G1 positive correlations of RBP4 with BMI (r = 0.253), glycated hemoglobin (r = 0.378) and fasting insulin (r = 0.336); in G2 with glycated hemoglobin (r = 0.489); in G3 with glycated hemoglobin (r = 0.330), fasting glucose (r = 0.463), HOMA-IR (r = 0.481). Conclusions: Although RBP4 have shown lower levels in diabetic and obese, a strong correlation with HOMA-IR index highlights that, in our study, there is growing IR when there is an increasing in RBP4 levels.
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dc.languageen
dc.publisherSociedade Brasileira de Endocrinologia e Metabologia
dc.relationArquivos Brasileiros de Endocrinologia e Metabologia
dc.rightsaberto
dc.sourceScopus
dc.titleSerum Levels Of Retinol Binding Protein 4 In Women With Different Levels Of Adiposity And Glucose Tolerance [níveis Séricos Da Proteína Carreadora Do Retinol 4 Em Mulheres Com Diferentes Níveis De Adiposidade E Tolerância à Glicose]
dc.typeArtículos de revistas


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