Effects Of Conjugated Linoleic Acid On Animal Metabolism: Advances In Research And Perspectives For The Future [os Efeitos Do ácido Linoléico Conjugado No Metabolismo Animal: Avanço Das Pesquisas E Perspectivas Para O Futuro]

dc.creatorSantos-Zago L.F.
dc.creatorBotelho A.P.
dc.creatorDe Oliveira A.C.
dc.date2008
dc.date2015-06-30T19:37:56Z
dc.date2015-11-26T14:46:18Z
dc.date2015-06-30T19:37:56Z
dc.date2015-11-26T14:46:18Z
dc.date.accessioned2018-03-28T21:55:56Z
dc.date.available2018-03-28T21:55:56Z
dc.identifier
dc.identifierRevista De Nutricao. , v. 21, n. 2, p. 195 - 221, 2008.
dc.identifier14155273
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-46949097579&partnerID=40&md5=d4c6e85998ade501bd2b2097da84310b
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/106921
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/106921
dc.identifier2-s2.0-46949097579
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1252785
dc.descriptionThis systematic review without date restrictions is about the physiological effects of conjugated linoleic acid on regression of carcinogenesis, oxidative stress, glucose and lipid metabolism and change in body composition. The objective was to establish the historical aspect of research advances regarding conjugated linoleic acid, considering original articles reporting work on animals, cell cultures and humans. Regarding the researches on the anticarcinogenic effect of conjugated linoleic acid, innumerous evidences were found in this respect, especially in the regression of mammary and colon tumors induced by both isomers which act distinctively. The researchers devoted considerable effort to reinvestigate the antioxidant properties of conjugated linoleic acid. Although the antioxidant properties have been investigated, pro-oxidant effect has been identified leading to oxidative stress in humans. Few studies demonstrated significant beneficial effects of conjugated linoleic acid on the metabolism of lipids and glucose and on the reduction of body fat, especially in humans. Studies with adverse effects were also identified. There is strong indication that the action of this conjugated fatty acid on a class of transition factors - the peroxisome proliferator-activated receptor - and on the consequent modulation of gene expression can be the fundamental explanation of its physiological effects. The most recent studies reinforce the nutrigenomic concept, that is, the modulation of gene expression induced by compounds present in the foods consumed by humans. This current scenario stimulates the scientific community to seek a consensus on the effects of conjugated linoleic acid in humans, since it is naturally found in some foods; when these foods are consumed regularly and in appropriate amounts, they could help prevent and control innumerous chronic diseases.
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dc.languagept
dc.publisher
dc.relationRevista de Nutricao
dc.rightsaberto
dc.sourceScopus
dc.titleEffects Of Conjugated Linoleic Acid On Animal Metabolism: Advances In Research And Perspectives For The Future [os Efeitos Do ácido Linoléico Conjugado No Metabolismo Animal: Avanço Das Pesquisas E Perspectivas Para O Futuro]
dc.typeArtículos de revistas


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