dc.creatorMazzafera P.
dc.creatorGoncalves K.V.
dc.creatorShimizu M.M.
dc.date2008
dc.date2015-06-30T19:19:47Z
dc.date2015-11-26T14:42:11Z
dc.date2015-06-30T19:19:47Z
dc.date2015-11-26T14:42:11Z
dc.date.accessioned2018-03-28T21:49:37Z
dc.date.available2018-03-28T21:49:37Z
dc.identifier
dc.identifierNatural Product Communications. , v. 3, n. 9, p. 1411 - 1422, 2008.
dc.identifier1934578X
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-77954140206&partnerID=40&md5=0f6b6cc44b999b2a961861bf50d19e68
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/105782
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/105782
dc.identifier2-s2.0-77954140206
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1251162
dc.descriptionComfrey, a medicinal herb with healing properties that are attributed to allantoin, was studied in this work. The accumulation and metabolism of allantoin (ALN) and its degradation product, allantoic acid (ALA), were examined. ALN was the main ureide in leaves and roots, with young leaves showing the highest content. ALA was the predominant ureide in the xylem sap, and together with ALN represented 27% of the nitrogen (N) transported in the xylem. Amino acids were the most abundant Ncompound in the xylem sap with a high proportion of glutamine. [ 14C]Xanthine feeding experiments showed that ALN and ALA were actively formed in leaves and roots by degradation of xanthine. Both xanthine and uric acid were rapidly degraded to form ALN and ALA. Enzyme studies showed that calculated V max/K m are low for allantoinase and alantoicase, supporting the results from the feeding experiments, and indicating that accumulation of ALN in comfrey is due to a low capacity for the enzymatic degradation of ureides.
dc.description3
dc.description9
dc.description1411
dc.description1422
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dc.languageen
dc.publisher
dc.relationNatural Product Communications
dc.rightsfechado
dc.sourceScopus
dc.titleControl Of Allantoin Accumulation In Comfrey
dc.typeArtículos de revistas


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