Importance Of Regulatory Cytokine Gene Polymorphisms In Hematopoietic Stem Cell Transplantation [importância De Polimorfismos De Genes Reguladores De Citocinas Em Transplantes De Células Progenitoras Hematopoiéticas]

dc.creatorVisentainer J.E.L.
dc.creatorSell A.M.
dc.creatorFranceschi D.A.
dc.creatorLieber S.R.
dc.creatorDe Souza C.A.
dc.date2008
dc.date2015-06-30T19:14:02Z
dc.date2015-11-26T14:39:48Z
dc.date2015-06-30T19:14:02Z
dc.date2015-11-26T14:39:48Z
dc.date.accessioned2018-03-28T21:45:42Z
dc.date.available2018-03-28T21:45:42Z
dc.identifier
dc.identifierRevista Brasileira De Ciencias Farmaceuticas/brazilian Journal Of Pharmaceutical Sciences. , v. 44, n. 4, p. 739 - 748, 2008.
dc.identifier15169332
dc.identifier10.1590/S1516-93322008000400021
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-59649125596&partnerID=40&md5=3f0fd4239d0c48894dafc37cbc3cf895
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/105353
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/105353
dc.identifier2-s2.0-59649125596
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1250148
dc.descriptionHLA genetic matching of donor and recipient is an important requirement for optimizing outcome following hematopoietic stem cell transplantation (HSCT). However, other non-HLA genes are being investigated for their role in graft-versus-host disease incidence and severity and in survival, by modulating the intensity of inflammation and tissue injury. These non-HLA-encoded genes include cytokine genes with polymorphisms within the 5' or 3' regulatory sequences of the genes. The polymorphisms or microsatellites may alter the transcription factor binding sites within the gene promoters and the amount of cytokine produced. This chapter summarizes the potential role of these genetic polymorphisms regarding the cytokines in predicting outcome of HSCT.
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dc.languagept
dc.publisher
dc.relationRevista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences
dc.rightsfechado
dc.sourceScopus
dc.titleImportance Of Regulatory Cytokine Gene Polymorphisms In Hematopoietic Stem Cell Transplantation [importância De Polimorfismos De Genes Reguladores De Citocinas Em Transplantes De Células Progenitoras Hematopoiéticas]
dc.typeArtículos de revistas


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