dc.creatorFigueiredo E.C.
dc.creatorDias A.C.B.
dc.creatorArruda M.A.Z.
dc.date2008
dc.date2015-06-30T19:14:00Z
dc.date2015-11-26T14:39:46Z
dc.date2015-06-30T19:14:00Z
dc.date2015-11-26T14:39:46Z
dc.date.accessioned2018-03-28T21:45:39Z
dc.date.available2018-03-28T21:45:39Z
dc.identifier
dc.identifierRevista Brasileira De Ciencias Farmaceuticas/brazilian Journal Of Pharmaceutical Sciences. , v. 44, n. 3, p. 361 - 375, 2008.
dc.identifier15169332
dc.identifier10.1590/S1516-93322008000300005
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-55849114045&partnerID=40&md5=a1571adf5a3f2bf685d7c16b11e3ac35
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/105351
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/105351
dc.identifier2-s2.0-55849114045
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1250133
dc.descriptionBiomolecular interactions (antigen-antibody, enzymesubstrate and drug-receptor) have been investigated due to their selective nature. Thus, since 1940, the search for synthetic materials presenting specific binding sites has been increasing. Nowadays, they are well established in different science areas such as pharmacy, analytical chemistry, biochemistry, among others, being the referred materials called molecularly imprinted polymers-MIP. Although the largest applications of MIP are found in the separations science field, few applications of these polymers have been reported as drug delivery systems-DDS. Such applications have been promising due to the feasibility of the MIP synthesis. However, the clinical use of the MIP as DDS is still not observed, probably due to its recent application, as well as extensive tests necessary for its approval as a new pharmaceutical form. In this way, this work aims to present the most recent progresses in the use of MIP as DDS, reinforcing the most significant aspects of this application (potentialities and limitations), as well as classifying and detailing such systems.
dc.description44
dc.description3
dc.description361
dc.description375
dc.descriptionALLENDER, C.J., RICHARDSON, C., WOODHOUSE, B., HEARD, C.M., BRAIN, K.R., Pharmaceutical applications for molecularly imprinted polymers (2000) Int. J. Pharm, 195 (1-2), pp. 39-43
dc.descriptionALVAREZ-LORENZO, C., CONCHEIRO, A., Molecularly imprinted polymers for drugs delivery (2004) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 804 (1), pp. 231-245
dc.descriptionALVAREZ-LORENZO, C., GUNEY, O., OYA, T., SAKAI, Y., KOBAYASHI, M., ENOKI, T., TAKEOKA, Y., GROSBERG, A.Y., Reversible adsorption of calsium ions by imprinted temperature sensitive gels (2001) J. Chem. Phys, 114 (6), pp. 2812-2816
dc.descriptionALVAREZ-LORENZO, C., YAÑEZ, F., BARREIROIGLESIAS, R., CONCHEIRO, A., Imprinted soft contact lenses as norfloxacin delivery systems (2006) J. Control. Release, 113 (3), pp. 236-244
dc.descriptionANDERSSON, L., SELLERGREN, B., MOSBACH, K., Imprinting of amino acid derivatives in macroporous polymers (1984) Tetrahedron Lett, 25 (45), pp. 5211-5214
dc.descriptionARSHADY, R., MOSBACH, M., Synthesis of substrate-selective polymers by host-guest polymerization (1981) Macromol. Chem. Phys, 182 (2), pp. 687-692
dc.descriptionAYDIN, O., ATTILA, G., DOGAN, A., AYDIN, M.V., CANACANKATAN, N., KANIK, A., The effects of methyl methacrylate on nasal cavity, lung, and antioxidant system (an experimental inhalation study) (2002) Toxicol. Pathol, 30 (3), pp. 350-356
dc.descriptionAZEVEDO, M.M.M. Nanoesfereas e a liberação controlada de fármacos. In: WORKSHOP DO CURSO: TÓPICOS ESPECIAIS EM QUÍMICA INORGÂNICA IV - INTRODUÇÃO À NANOTECNOLOGIA: UM ENFOQUE QUÍMICO, 1, Campinas, 2002. Disponível em: 〈http://lqes.iqm.unicamp.br/images/ vivencia_lqes_monografias_marcelo_nanoesferas.pdf〉. Acesso em: 08 maio 2007BERZELIUS, J.J., (1835) Jahresber. Chem, 15, pp. 242-244
dc.descriptionCHEN, G., GUAN, Z., CHEN, C., FU, L., SUNDARESAN, V., ARNALD, F.H., A glucose-sensing polymer (1997) Nat. Biotechnol, 15 (4), pp. 354-357
dc.descriptionCHIEN, Y.W., LIN, S., Optimisation of treatment by applying programmable rate-controlled drug delivery technology (2002) Clin. Pharmacokinet, 41 (15), pp. 1267-1300
dc.descriptionCHUNG, J.E., YOKOYAMA, M., OKANO, T., Inner core segment design for drug delivery control of thermoresponsive polymeric micelles (2000) J.Control. Release, 65 (1-2), pp. 93-103
dc.descriptionCIARDELLI, G., CIONI, B., CRISTALLINI, C., BARBANI, N., SILVESTRI, D., GIUSTI, P., Acrylic polymeric nanospheres for the release and recognition of molecules of clinical interest (2004) Biosens. Bioelectron, 20 (6), pp. 1083-1090
dc.descriptionCORMACK, P.A.G., ELORZA, A.Z., Molecularly imprinted polymers: Synthesis and characterization (2004) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 804 (1), pp. 173-182
dc.descriptionCUNLIFFE, D., KIRBY, A., ALEXANDER, C., Molecularly imprinted drug delivery systems (2005) Adv. Drug Deliv. Rev, 57 (12), pp. 1836-1853
dc.descriptionDICKEY, F.H., The preparation of specific adsorbents (1949) Proc. Natl. Acad. Sci, 35 (5), pp. 227-229
dc.descriptionN.
dc.descriptionDE AZEVEDO, M.M. O que é nanotecnologia? Atualidades e perspectivas, , http://www.ifi.unicamp.br/extensao/downloads/nanobiotecnologia.doc〉.Acesso, DURÁN, Disponível em:, 15 jun. 2007
dc.descriptionFIUME, M.Z., Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients (2002) In. J. Toxicol, 21 (3), pp. 1-50
dc.descriptionGLAD, M., REINHOLDSSON, P., MOSBACH, K., Molecularly imprinted composite polymers based on trimethylolpropane trimethacrylate (TRIM) particles for efficient enantiomeric separations (1995) React. Poly, 25 (1), pp. 47-54
dc.descriptionGRAYSON, A.C.R., CHOI, I., TYLER, B.M., WANG, P.P., BREM, H., CIMA, M.J., LANGER, R., Multi-pulse drug delivery from a resorbable, polymeric microchip device (2003) Nat. Mater, 2 (11), pp. 767-772
dc.descriptionHAGINAKA, J., Monodispersed, molecularly imprinted polymers as affinity-based chromatography media (2008) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 866 (1-2), pp. 3-13
dc.descriptionHAGINAKA, J., SANBE, H., TAKEHIRA, H., Uniformsized molecularly imprinted polymer for (S)-ibuprofen retention properties in aqueous mobile phases (1999) J. Chromatogr., A, 857 (1-2), pp. 117-125
dc.descriptionHILLBERG, A.L., BRAIN, K.R., ALLENDER, C.J., Molecular imprinted polymer sensors: Implications for therapeutics (2005) Adv. Drug Deliv. Rev, 57 (12), pp. 1875-1889
dc.descriptionHILT, J.Z., BYRNE, M.E., Configurational biomimesis in drug delivery: Molecular imprinting of biologically significant molecules (2004) Adv. Drug Delivery Rev, 56 (11), pp. 1599-1620
dc.descriptionHIRATANI, H., ALVAREZ-LORENZO, C., Timolol uptake and release by imprinted soft contact lenses made of N,N-dimethylacrylamine and methacrylic acid (2002) J. Control. Release, 83 (2), pp. 223-230
dc.descriptionHIRATANI, H., FUJIWARA, A., TAMIYA, Y., MIZUTANI, Y., ALVAREZ-LORENZO, C., Ocular release of timolol from molecularly imprinted soft contact lenses (2005) Biomaterials, 26 (11), pp. 1293-1298
dc.descriptionHIROKAWA, Y., TANAKA, T., Volume phase transition in a nonionic gel (1984) J. Chem. Phys, 81 (12), pp. 6379-6380
dc.descriptionHOFFMAN, A.S., Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics (1987) J. Control. Release, 6 (1), pp. 297-305
dc.descriptionJANTARAT, C., TANGTHONG, N., SONGKRO, S., MARTIN, G.P., SUEDEE, R., S-Propranolol imprinted polymer nanoparticle-on-microsphere composite porous cellulose membrane for the enantioselectively controlled delivery of racemic propranolol (2008) Int. J. Pharm, 349 (1-2), pp. 212-225
dc.descriptionKAPARISSIDES, C., ALEXANDRIDOU, S., KOTTI, K., CHAITIDOU, S., Recent advances in novel drug delivery systems (2006) J. Nanotechynol. Online, 2, pp. 1-11
dc.descriptionKARLSSON, J.G., ANDERSSON, L.I., NICHOLLS, I.A., Probing the molecular basis for ligand-selective recognation in molecularly imprinted polymers for the local anesthetic bupivacaine (2001) Anal. Chim. Acta, 435 (1), pp. 57-64
dc.descriptionKARMALKAR, R.N., KULKARNI, M.G., MASHELKAR, R.A., Pendent chain linked delivery systems: II. Facile hydrolysis through molecular imprinting effects (1997) J. Control. Release, 43 (2-3), pp. 235-243
dc.descriptionKATAOKA, K.
dc.descriptionMIYAZAKI, H.
dc.descriptionBUNYA, M.
dc.descriptionOKANO, T.
dc.descriptionSAKURAI, Y. On-off regulation of insulin-release by totally synthetic polymer gels responding to external glucose concentration. Polym. Prepr., Abstracts of Papers of the American Chemical Society, v.217, n.165-Poly, p.U564-U564, 1999KHAJEH, M., YAMINI, Y., GHASEMI, E., FASIHI, J., SHAMSIPUR, M., Imprinted polymer particles for selenium uptake: Synthesis, characterization and analytical applications (2007) Anal. Chim. Acta, 581 (2), pp. 208-213
dc.descriptionKIM, I.S., JEONG, Y.I., CHO, C.S., KIM, S.H., Core-shell type polymeric nanoparticles composed of poly(L-lactic acid) and poly(N- isopropylacrylamide (2000) Int. J. Pharm, 211 (1-2), pp. 1-8
dc.descriptionLEE, W.F., YEN, S.H., Thermoreversible hydrogels. XII. Effect of the polymerization conditions on the swelling behavior of the N-isopropylacrylamide gel (2000) J. Appl. Polym. Sci, 78 (9), pp. 1604-1611
dc.descriptionLIMBIRD, L.E., The Receptor Concept: A Continuing Evolution (2004) Mol. Interv, 4, pp. 326-336
dc.descriptionMAGALHÃES, C.S., GARCIA, J.S.
dc.descriptionLOPES, A.S.
dc.descriptionFIGUEIREDO, E.C.
dc.descriptionARRUDA, M.A.Z. Strategies for sample preparation focusing on biomolecules determination/caracterization In: ARRUDA, M.A.Z. (Eds.). Trends in sample preparation. New York: Nova Science Publishers, 2007. cap.9, p.245-288MARTÍN-ESTEBAN, A., Molecularly imprinted polymers: New molecular recognation materials for selective solid-phase extraction of organic compounds (2001) Fresenius J. Anal. Chem, 370 (7), pp. 795-802
dc.descriptionMATSUI, J., OKADA, M., TSURUOKA, M., TAKEUCHI, T., Solid-phase extraction of a triazine herbicide using a molecularly imprinted synthetic receptor (1997) Anal. Commun, 34 (3), pp. 85-87
dc.descriptionMAYES, A.G., MOSBACH, K., Molecularly imprinted polymer beads: Suspension polymerization using a liquid perfluorocarbon as the dispersing phase (1996) Anal. Chem, 68 (21), pp. 3769-3774
dc.descriptionMIYATA, T., URAGAMI, T., NAKAMAE, K., Biomolecule-sensitive hydrogels (2002) Adv. Drug Del. Rev, 54 (1), pp. 79-98
dc.descriptionMORITANI, T., ALVAREZ-LORENZO, C., Conformational imprinting effect on stimuli-sensitive gels made with an "imprinter" monomer (2001) Macromolecules, 34 (22), pp. 7796-7803
dc.descriptionNICHOLLS, I.A., ADBO, K., ANDERSSON, H.S., ANDERSSON, P.O., ANKARLOO, J., HEDINDAHLSTROM, J., JOKELA, P., WIKMAN, S., Can we rationally design molecularly imprinted polymers? (2001) Anal. Chim. Acta, 435 (1), pp. 9-18
dc.descriptionNORELL, M.C., ANDERSSON, H.S., NOCHOLLS, I.A., Theophylline molecularly imprinted polymer dissociation kinetics: A novel sustained realease drug dosage mechanism (1998) J. Mol. Recog, 11 (1-6), pp. 98-102
dc.descriptionOKANO, T., BAE, Y.H., JACOBS, H., KIM, S.W., Thermally on-off switching polymers for drug permeation and release (1990) J. Control. Release, 11 (1-3), pp. 255-265
dc.descriptionPAULING, L.J., A Theory of the structure and process of formation of antibodies (1940) J. Am. Chem. Soc, 62 (10), pp. 2643-2657
dc.descriptionPHILIP, J.Y.N., BUCHWEISHAIJA, J., MKAYULA, L.L., YE, L., Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid (2007) J. Agric. Food Chem, 55 (22), pp. 8870-8876
dc.descriptionPUOCI, F., IEMMA, F., CIRILLO, G., PICCI, N., MATRICARDI, P., ALHAIQUE, A., Molecularly Imprinted Polymers for 5-Fluorouracil Release in Biological Fluids (2007) Molecules, 12 (4), pp. 805-814
dc.descriptionPUOCI, F., IEMMA, E., MUZZALUPO, R., SPIZZIRRI, U.G., TROMBINO, S., CASSANO, R., PICCI, N., Spherical Molecularly Imprinted Polymers (SMIPs) via a Novel Precipitation Polymerization in the Controlled Delivery of Sulfasalazine (2004) Macromol. Biosc, 4 (1), pp. 22-26
dc.descriptionRAMSTRÖM, O., ANDERSSON, L.I., MOSBACH, K., Recognition sites incorporating both pyridinyl and carboxy functionalities prepared by molecular imprinting (1993) J. Org. Chem, 58 (26), pp. 7562-7564
dc.descriptionRICKA, J., TANAKA, T., Phase transition in ionic gels induced by copper complexation (1985) Macromol, 18 (1), pp. 83-85
dc.descriptionSANTINI Jr., J.T., CIMA, M.J., LANGER, R., A controlled-release microchip (1999) Nature, 397, pp. 335-338
dc.descriptionSELLERGREN, B., ALLENDER, C.J., Molecularly imprinted polymers: A bridge to advanced drug delivery (2005) Adv. Drug Delivery Rev, 57 (12), pp. 1733-1741
dc.descriptionSELLERGREN, B.
dc.descriptionHALL, A. J. Fundamental aspects on the synthesis and characterisation of imprinted network polymers
dc.descriptionIn: SELLERGREN, B. (Ed.). Molecularly imprinted polymers: Man-made mimics of antibodies and their applications in analytical chemistry. Amsterdam: Elsevier, 2001. cap.2, p. 21-57SELLERGREN, B., LEPISTÖ, M., MOSBACH, K., Highly Enantioselective and substrate-selective polymers obtained by molecular imprinting utilizing noncovalent interactions. NMR and chromatographic studies on the nature of recognition (1988) J. Am. Chem. Soc, 110 (17), pp. 5853-5860
dc.descriptionSREENIVASAN, K., Imparting cholesterol recognition sites in radiation polymerised poly(2-hydroxyethyl methacrylate) by molecular imprinting (1997) Polym. Int, 42 (2), pp. 169-172
dc.descriptionSREENIVASAN, K., On the aplication of molecularly imprinted poly(HEMA) as a template responsive realise system (1999) J. Appl. Polym, Sci, 71 (11), pp. 1819-1821
dc.descriptionSTRIEGLER, S., Selective discrimination of closely related monosaccharides at physiological pH a polymeric receptor (2001) Tetrahedron, 57 (12), pp. 2349-2354
dc.descriptionSTRIEGLER, S., Investigation of disaccharide recognition by molecularly imprinted polymers (2002) Bioseparation, 10 (6), pp. 307-314
dc.descriptionSTRIEGLER, S., Carbohydrate recognition in cross-linked sugar-templated poly(acrylates) (2003) Macromol, 36 (4), pp. 1310-1317
dc.descriptionSUEDEE, R., SRICHANA, T., RATTANANONT, T., Enantioselective release of contolled delivery granules based on molecularly imprintd polymers (2002) Drug Delivery, 9 (1), pp. 19-30
dc.descriptionTARLEY, C.R.T., SOTOMAYOR, M.P.T., KUBOTA, L.T., Polímeros Biomiméticos em Química Analítica. Parte 1: Preparo e Aplicações de MIP (Molecularly Imprinted Polymers) em Técnicas de Extração e Separação. (2005) Quim. Nova, 28 (6), pp. 1076-1086
dc.descriptionTHE UNITED STATES PHARMACOPEIA. 24. ed. Rockville: United States Pharmacopeial Convention, 2000. p.1577UCHIMURA, E., OTSUKA, H., OKANO, T., SAKURAI, Y., KATAOKA, K., Totally synthetic polymer with lectin-like function: Induction of killer cells by the copolymer of 3-acrylamidophenilboronic acid with n,ndimethylacrylamide (2001) Biotechnol. Bioeng, 72 (3), pp. 307-314
dc.descriptionULUBAYRAM, K., TUNC, Y., BAYKARA, E., Molecularly imprinted acrylic-based microspheres for colonic delivery of 5-aminosalicylic acid (2007) J. Optoelectron. Adv. Mater, 9 (11), pp. 3479-3483
dc.descriptionVLATAKIS, G., ANDERSSON, L.I., MÜLLER, R., MOSBACH, K., Drug assay using antibody mimics made by molecularly imprinting (1993) Nature, 361, pp. 645-647
dc.descriptionWANG, J.F., CORMARCK, P.A.G., SHERRINGTON, D.C., KHOSHDEL, E., Monodisperse, molecularly imprinted polymer microspheres prepared by precipitation polymerization for affinity separation applications (2003) Angew. Chem, 42 (43), pp. 5336-5338
dc.descriptionWANG, X.B., DING, X.B., ZHENG, Z.H., HU, X.H., CHENG, X., PENG, Y.X., Magnetic molecularly imprinted polymer particles synthesized by suspension polymerization in silicone oil (2006) Macromol. Rapid Commun, 27 (14), pp. 1180-1184
dc.descriptionWHITCOMBE, M.J., RODRIGUEZ, M.E., VILLAR, P., VULFSON, E.N., A new method for the introduction of recognition site functionality into polymers prepared by molecular imprinting - synthesies and characterization of polymeric recptors for cholesterol (1995) J. Am. Chem. Soc, 117 (27), pp. 7105-7111
dc.descriptionWOLMAN, F.J., SMOLKO, E.E., CASCONE, O., GRASSELLI, M., Peptide imprinted polymer synthesized by radiation-induced graft polymerization (2006) React. Funct. Polym, 66 (11), pp. 1199-1205
dc.descriptionWULFF, G., SARHAN, A., Über die Anwendung von enzymanalog gebauten Polymeren zur Racemattrennung (1972) Angew. Chem, 84 (8), p. 364
dc.descriptionYE, L., CORMACK, P.A.G., MOSBACH, K., Molecularly imprinted monodisperse microspheres for competitive radioassay (1999) Anal. Commun, 36 (2), pp. 35-38
dc.descriptionYE, L., CORMACK, P.A.G., MOSBACH, K., Molecular imprinting on microgel spheres (2001) Anal. Chim. Acta, 435 (1), pp. 187-196
dc.descriptionYILMAZ, E., RAMSTRÖM, O., MÖLLER, P., SANCHEZC, D., MOSBACHA, K., A facile method for preparing molecularly imprinted polymer spheres using spherical silica templates (2002) J. Mater. Chem, 12, pp. 1577-1581
dc.descriptionYOSHIMATSU, K., REIMHULT, K., KROZER, A., MOSBACH, K., SODE, K., YE, L., Uniform molecularly imprinted microspheres and nanoparticles prepared by precipitation polymerization: The control of particle size suitable for different analytical applications (2007) Anal. Chim. Acta, 584 (1), pp. 112-121
dc.descriptionYUK, S.H., BAE, Y.H., Phase-transition polymers for drug delivery (1999) Crit. Rev. Ther. Drug Carrier Syst, 16 (4), pp. 385-423
dc.languagept
dc.publisher
dc.relationRevista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences
dc.rightsfechado
dc.sourceScopus
dc.titleMolecular Imprinting: A Promising Strategy In Matrices Elaboration For Drug Delivery Systems [impressão Molecular: Uma Estratégia Promissora Na Elaboração De Matrizes Para A Liberação Controlada De Fármacos]
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución