dc.creator | Syrjanen K. | |
dc.creator | Derchain S. | |
dc.creator | Roteli-Martins C. | |
dc.creator | Longatto-Filho A. | |
dc.creator | Hammes L.S. | |
dc.creator | Sarian L. | |
dc.creator | Naud P. | |
dc.creator | Tatti S. | |
dc.creator | Branca M. | |
dc.creator | Erzen M. | |
dc.creator | Matos J. | |
dc.creator | Gontijo R. | |
dc.creator | Braganca J. | |
dc.creator | Arlindo F. | |
dc.creator | Maeda M.Y.S. | |
dc.creator | Lorincz A. | |
dc.creator | Dores G.B. | |
dc.creator | Costa S. | |
dc.creator | Syrjanen S. | |
dc.date | 2008 | |
dc.date | 2015-06-30T19:12:34Z | |
dc.date | 2015-11-26T14:39:31Z | |
dc.date | 2015-06-30T19:12:34Z | |
dc.date | 2015-11-26T14:39:31Z | |
dc.date.accessioned | 2018-03-28T21:45:14Z | |
dc.date.available | 2018-03-28T21:45:14Z | |
dc.identifier | | |
dc.identifier | Acta Cytologica. S. Karger Ag, v. 52, n. 6, p. 641 - 653, 2008. | |
dc.identifier | 15547 | |
dc.identifier | | |
dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-44349125420&partnerID=40&md5=d74aef23a733eaf88d7dbccb7ff06c74 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/105255 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/105255 | |
dc.identifier | 2-s2.0-44349125420 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1250031 | |
dc.description | Objective: To compare performance of conventional Pap test, liquid-based cytology (LBC) and visual inspection with acetic acid (VIA), as well as human papillomavirus (HPV) testing in 2 subcohorts of women, < 35 and ≥ 35 years of age. Study Design: Performance indicators were calculated using colposcopic biopsies as the gold standard; all results were corrected for verification bias using maximum likelihood. Results: Both conventional Pap test and Hybrid Capture 2 (HC2) assay performed significantly better among older women than younger; no difference was observed in performance of LBC and VIA, both inferior to Pap and HC2. The Pap test was more specific than HC2 in both subcohorts; HC2 had the highest sensitivity. For individual tests, the best balance between sensitivity and specificity was obtained for HC2 assay corrected for verification bias in the older women's subcohort; this was further improved by the combined use of the Pap test and HC2. Conclusion: Age of the target population is an important determinant of the performance of different screening tests. The choice of optimal test for women < 35 and ≥ 35 years of age depends on whether the highest positive predictive value (Pap test) or the best SE/SP balance (HC2) is used as the selection criterion. © The International Academy of Cytology. | |
dc.description | 52 | |
dc.description | 6 | |
dc.description | 641 | |
dc.description | 653 | |
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dc.language | en | |
dc.publisher | S. Karger AG | |
dc.relation | Acta Cytologica | |
dc.rights | fechado | |
dc.source | Scopus | |
dc.title | Value Of Conventional Pap Smear, Liquid-based Cytology, Visual Inspection And Human Papillomavirus Testing As Optional Screening Tools Among Latin American Women < 35 And ≥ 35 Years Of Age: Experience From The Latin American Screening Study | |
dc.type | Artículos de revistas | |