Prolactine (PRL) and progesterone were systematically measured in all women presenting with amenorrhea, oligomenorrhea or galactorrhea at the Infertility Clinic of the Department of Obstetrics and Gynecology, State University of Campinas, Brazil, during a period of 34 months. The same hormonal assays were done to all infertile patients presenting for the first time during the last 6 months of the same period, for a total of 190 subjects. Fifty-five patients with amenorrhea, 38 with oligomenorrhea and 97 with normal cycles, 20 of whom had galactorrhea, were included in the study. Fifty-five percent of amenorrheic patients, 37% of oligomenorrheic and 9% of those with normal menses had elevated PRL. The mean PRL was higher the greater the menstrual disturbance but was not influenced by presence or absence of galactorrhea. Short luteal phase was the ovarian function condition most frequently associated with high PRL among women with normal menses. © 1985.2313136Bahamondes, Saboya, Tambascia, Trevisan, Galactorrhea, infertility and short luteal phase in hyperprolactinemic women: early stage of amenorrhea-galactorrhea? (1979) Fertil Steril, 32, p. 476Bahamondes, Tambascia, Motta Collier, Faúndes, Pinotti, Estudo das gonadotropinas hipofisárias, estradiol e progesterona por radioimunoensaio, durante o ciclo menstrual normal em mulheres brasileiras (1980) Rev Bras Gin Ob, 2, p. 82Davajan, Kletzky, March, Roy, Mishell, Significance of galactorrhea in patients with normal menses, oligomenorrhea and secondary amenorrhea (1978) Am J Obstet Gynecol, 130, p. 894Del Pozo, Wyss, Tolis, Alcañiz, Campana, Naftolin, Prolactin and deficient luteal function (1979) Obstet Gynecol, 53, p. 282Delvoye, Tauber, Jurgensen, Effect of methylergobasine maleate on serum gonadotrophin and prolactin in humans. Acta Endocrinol (Copenh), , (KBH Suppl)Kleinberg, Noel, Frants, Galactorrhea: a study of 235 cases, including 48 pituitary tumors (1977) New Engl J Med, 296, p. 589McNatty, Sawers, McNeilly, A possible role for prolactin in control of steroid secretion by the human Graafin follicle (1974) Nature, 250, p. 653Pepperell, Evans, Brown, Smith, Healy, Burger, Serum prolactin levels and the value of bromocriptine in the treatment of anovulatory infertility (1977) Br J Obstet Gynaecol, 84, p. 58Seppäla, Hirvonen, Ranta, Virkkunen, Lappaluoto, Raised serum prolactin levels in amenorrhoea. (1975) BMJ, 2, p. 305Seppäla, Hirvonen, Ranta, Hyperprolactinemia and luteal insufficiency (1976) Lancet, 1, p. 299Shearman, Frase, Impact of new diagnostic methods on the differential diagnosis and treatment of secondary amenorrhea (1977) Lancet, 1, p. 1195Tambascia, Bahamondes, Pinotti, Motta Collier, Dachs, Faúndes, Sustained hyperprolactinemia in a normally menstruating woman with apparently normal ovarian function (1980) Fertil Steril, 34, p. 282