Thyroid Function In Hemidecorticate Rats.

dc.creatorMunhoz C.O.
dc.creatorTosello D.O.
dc.creatorFernandez G.A.
dc.creatorMerzel J.
dc.date1988
dc.date2015-06-30T13:40:22Z
dc.date2015-11-26T14:36:39Z
dc.date2015-06-30T13:40:22Z
dc.date2015-11-26T14:36:39Z
dc.date.accessioned2018-03-28T21:40:38Z
dc.date.available2018-03-28T21:40:38Z
dc.identifier
dc.identifierBrazilian Journal Of Medical And Biological Research. , v. 21, n. 5, p. 949 - 955, 1988.
dc.identifier0100879X
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0024269195&partnerID=40&md5=b7c194cfdd2509946406f1f63832119b
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/98132
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/98132
dc.identifier2-s2.0-0024269195
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1248845
dc.description1. Thyroid function was evaluated in hemidecorticate (HD) and control (C) rats by determining serum T3 and T4 levels and the development of incisors and mandibles and through analysis of various histological features of the thyroid such as follicle size, colloid droplet content and [3H]-glycine uptake by follicular cells. 2. HD animals presented normal levels of circulating T3 but significantly lower T4 levels. 3. There was slight atrophy of the gland in HD animals and fewer colloid droplets were present in the cytoplasm of the follicular cells in this group, indicating a reduction in the breakdown of thyroglobulin. [3H]-glycine uptake by HD indicated that the rate of thyroglobulin biosynthesis was not altered in the experimental animals. 4. The growth of mandibles (weight) and incisors (weight and length) was reduced in HD compared to the control animals. 5. These results suggest that hemidecortication causes mild hypothyroidism (trophoprivic type) probably by affecting hypothalamic function.
dc.description21
dc.description5
dc.description949
dc.description955
dc.languageen
dc.publisher
dc.relationBrazilian Journal of Medical and Biological Research
dc.rightsaberto
dc.sourceScopus
dc.titleThyroid Function In Hemidecorticate Rats.
dc.typeArtículos de revistas


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