| dc.creator | Jorge S.E.C. | |
| dc.creator | Kimura E.M. | |
| dc.creator | Oliveira D.M. | |
| dc.creator | Ogo S. | |
| dc.creator | Albuquerque D.M. | |
| dc.creator | Costa F.F. | |
| dc.creator | Sonati M.D.F. | |
| dc.date | 2007 | |
| dc.date | 2015-06-30T18:47:14Z | |
| dc.date | 2015-11-26T14:35:39Z | |
| dc.date | 2015-06-30T18:47:14Z | |
| dc.date | 2015-11-26T14:35:39Z | |
| dc.date.accessioned | 2018-03-28T21:39:04Z | |
| dc.date.available | 2018-03-28T21:39:04Z | |
| dc.identifier | | |
| dc.identifier | Hemoglobin. , v. 31, n. 2, p. 151 - 157, 2007. | |
| dc.identifier | 3630269 | |
| dc.identifier | 10.1080/03630260701289425 | |
| dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-34248196518&partnerID=40&md5=ded03e6b06453d9c81f19b4da0db4c9a | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/104776 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/104776 | |
| dc.identifier | 2-s2.0-34248196518 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1248433 | |
| dc.description | Three novel α-globin variants were found during a screening program for hemoglobinopathies in blood donors at the UNICAMP Hematology and Hemotherapy Center, Campinas, State of São Paulo, Southeastern Brazil. They were named for the town of origin of the carrier as Hb Itapira [α30(B11) Glu→Val], Hb Bom Jesus da Lapa [α30(B11)Glu→Ala] and Hb Boa EsperanÇa [α16(A14)Lys→Thr]. Hb Itapira, like Hb Bom Jesus da Lapa, shows an electrophoretic mobility similar to that of Hb S [β6(A3)Glu→Val, GAG→GTG] at alkaline pH; it is associated with a triplicate α-globin allele (αααanti 3.7) and corresponds to only 5.5% of the total hemoglobin (Hb). Hb Boa EsperanÇa, found in two different individuals, moves faster than Hb A and exhibits an abnormal functional performance. Copyright © Informa Healthcare. | |
| dc.description | 31 | |
| dc.description | 2 | |
| dc.description | 151 | |
| dc.description | 157 | |
| dc.description | Hardison, R.C., Chui, D.H.K., Giardine, B., Riemer, C., Patrinos, G.P., Anagnou, N., Miller, W., Wajcman, H., HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server (2002) Hum Mutat, 19 (3), pp. 225-233. , http://globin.cse.psu.edu | |
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| dc.description | Dodé, C., Krishnamoorthy, R., Lamb, J., Rochette, J., Rapid analysis of ?α 3.7 thalassaemia and ααα anti 3.7 triplication by enzymatic amplification analysis (1993) Br J Haematol, 83 (1), pp. 105-111 | |
| dc.description | Rossi-Fanelli, A., Antonini, E., Studies on the oxygen and carbon monoxide equilibria of human hemoglobin (1958) Arch Biochem Biophys, 77 (2), pp. 478-492 | |
| dc.description | Chanutin, A., Curnish, R.R., Effect of organic and inorganic phosphates on the oxygen equilibrium of human erythrocytes (1967) Arch Biochem Biophys, 121 (1), pp. 96-102 | |
| dc.description | Benesch, R., Benesch, R.E., The effect of organic phosphates from the human erythrocyte on the allosteric properties of hemoglobin (1967) Biochem Biophys Res Commun, 26 (2), pp. 162-167 | |
| dc.description | Tan, A.S.C., Quah, T.C., Low, P.S., Chong, S.S., A rapid and reliable 7-deletion multiplex polymerase chain reaction assay for α-thalassemia (2001) Blood, 98 (1), pp. 250-251 | |
| dc.description | Antonini, E., Brunoni, M., (1970) Hemoglobin and Myoglobin in Their Reaction with Ligands, , 1st ed. Amsterdam: North-Holland Publishing Company | |
| dc.description | Vestri, R., Pieragostini, E., Yang, F., di Gregório, P., Rando, A., Masina, P., Expression of triplicated and quadruplicated α globin genes in sheep (1991) Br J Haematol, 77 (1), pp. 110-116 | |
| dc.description | Vestri, R., Pieragostini, E., Ristaldi, M.S., Expression gradient in sheep αα and ααα globin gene haplotypes: MRNA levels (1994) Blood, 83 (8), pp. 2317-2322 | |
| dc.language | en | |
| dc.publisher | | |
| dc.relation | Hemoglobin | |
| dc.rights | fechado | |
| dc.source | Scopus | |
| dc.title | Three New α-globin Variants: Hb Itapira [α30(b11)glu→val (α1)], Hb Bom Jesus Da Lapa [α30(b11)glu→ala (α1)] And Hb Boa Esperança [α16(a14)lys→thr (α2)] | |
| dc.type | Artículos de revistas | |
