Annona crassiflora (araticum), Solanum lycocarpum (lobeira), Eugenia dysenterica (cagaita), Caryocar brasilense (pequi) and Swartzia langsdorfii (banha de galinha) are tropical fruits consumed mainly by native people in the Brazilian Cerrado (second biggest biome of Brazil). In this study, pulp, seed and peel of the fruits were extracted using ethanol and water. Some of the extracts showed a high content of total phenols and were screened for their potential as antioxidants using the in vitro model 2,2-diphenyl-1-picryl hydrazyl (DPPH). The best results were found for aqueous and ethanolic extracts of pequi peel (IC50 of 9,44 and 17,98 μg.mL-1 respectively), etanolic extract of cagaita seeds (IC50 of 14,15 μg.mL-1), etanolic extract of araticum seeds and peel (IC 50 of 30,97 and 49,18 μg.mL-1 respectively). This is the first report on the antioxidant properties of the extracts of cerrado fruit fractions. 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