Metals And (metallo)proteins Identification In Vitreous Humor Focusing On Post-mortem Biochemistry

dc.creatorSantos Junior J.C.
dc.creatorMollo Filho P.C.
dc.creatorFelice Guidugli R.B.
dc.creatorEberlin M.N.
dc.creatorPessoa G.D.S.
dc.creatorDa Silva E.G.
dc.creatorArruda M.A.Z.
dc.creatorHoehr N.F.
dc.date2014
dc.date2015-06-25T17:54:15Z
dc.date2015-11-26T14:31:15Z
dc.date2015-06-25T17:54:15Z
dc.date2015-11-26T14:31:15Z
dc.date.accessioned2018-03-28T21:34:38Z
dc.date.available2018-03-28T21:34:38Z
dc.identifier
dc.identifierMetallomics. Royal Society Of Chemistry, v. 6, n. 10, p. 1801 - 1807, 2014.
dc.identifier17565901
dc.identifier10.1039/c3mt00373f
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84907613092&partnerID=40&md5=02d051044afea807e493fb06536a41d3
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/86643
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/86643
dc.identifier2-s2.0-84907613092
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1247327
dc.descriptionThis work describes the evaluation of metals and (metallo)proteins in vitreous humor samples and their correlations with some biological aspects in different post-mortem intervals (1-7 days), taking into account both decomposing and non-decomposing bodies. After qualitative evaluation of the samples involving 26 elements, representative metal ions (Fe, Mg and Mo) are determined by inductively coupled plasma mass spectrometry after using mini-vial decomposition system for sample preparation. A significant trend for Fe is found with post-mortem time for decomposing bodies because of a significant increase of iron concentration when comparing samples from bodies presenting 3 and 7 days post-mortem interval. An important clue to elucidate the role of metals is the coupling of liquid chromatography with inductively coupled plasma mass spectrometry for identification of metals linked to proteins, as well as mass spectrometry for the identification of those proteins involved in the post-mortem interval.
dc.description6
dc.description10
dc.description1801
dc.description1807
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dc.languageen
dc.publisherRoyal Society of Chemistry
dc.relationMetallomics
dc.rightsaberto
dc.sourceScopus
dc.titleMetals And (metallo)proteins Identification In Vitreous Humor Focusing On Post-mortem Biochemistry
dc.typeArtículos de revistas


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