dc.creatorSoares A.B.
dc.creatorLins L.H.S.
dc.creatorMacedo A.P.
dc.creatorPereira Neto J.S.
dc.creatorVargas P.A.
dc.date2006
dc.date2015-06-30T18:18:39Z
dc.date2015-11-26T14:29:29Z
dc.date2015-06-30T18:18:39Z
dc.date2015-11-26T14:29:29Z
dc.date.accessioned2018-03-28T21:32:43Z
dc.date.available2018-03-28T21:32:43Z
dc.identifier
dc.identifierMedicina Oral, Patologia Oral Y Cirugia Bucal. , v. 11, n. 3, p. 191 - 194, 2006.
dc.identifier16984447
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-33745074073&partnerID=40&md5=7958684ac96e0d7a788a16238596b90f
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/103916
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/103916
dc.identifier2-s2.0-33745074073
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1246855
dc.descriptionFibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this article we describe a case of primary fibrosarcoma in the mandible in a 16-year-old girl. Microscopically the tumor showed an intense proliferation of spindle-shaped cells, varying little in size and shape and arranged in parallel bands, partly crossing each other, the mitotic activity was increased and there was nuclear pleomorphism. Immunohistochemically the cells only showed immunoreactivity for vimentin and negativity for S-100 protein, CD 68, cytokeratin cocktail, HMB-45, CD34, pan actin HHF 35, desmin, smooth muscle actin and epithelial membrane antigen (EMA). Based on clinical, radiological, histological and immunohistochemical findings the final diagnosis was high-grade intra-osseous fibrosarcoma. The treatment choice was radical surgery with mandibular reconstruction. After one year and nine months of the treatment the patient displayed multiple metastases. Radiation therapy and chemotherapy were used as adjuvant treatment. Unfortunately, the girl died two years after the initial diagnosis. © Medicina Oral S. L. C.I.F. B 96689336.
dc.description11
dc.description3
dc.description191
dc.description194
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dc.languageen
dc.publisher
dc.relationMedicina Oral, Patologia Oral y Cirugia Bucal
dc.rightsaberto
dc.sourceScopus
dc.titleFibrosarcoma Originating In The Mandible
dc.typeArtículos de revistas


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