Evaluation Of The Effects Of Anthocyanins In Type 2 Diabetes

dc.creatorSancho R.A.S.
dc.creatorPastore G.M.
dc.date2012
dc.date2015-06-26T20:30:14Z
dc.date2015-11-26T14:28:50Z
dc.date2015-06-26T20:30:14Z
dc.date2015-11-26T14:28:50Z
dc.date.accessioned2018-03-28T21:32:03Z
dc.date.available2018-03-28T21:32:03Z
dc.identifier
dc.identifierFood Research International. , v. 46, n. 1, p. 378 - 386, 2012.
dc.identifier9639969
dc.identifier10.1016/j.foodres.2011.11.021
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84857648468&partnerID=40&md5=1da4c4cad95257573f215bb1e76cd594
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/97271
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/97271
dc.identifier2-s2.0-84857648468
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1246693
dc.descriptionThe number of cases of type 2 diabetes (T2D) is increasing worldwide. This disease can be characterized by insulin resistance and pancreatic β cell dysfunction, which lead to macro- and microvascular complications. Anthocyanins are flavonoids that occur naturally in plants and are responsible for their color. Studies with cell lines and animal models and clinical trials in humans suggest that anthocyanins exhibit antidiabetic properties. However, variation in the structure of anthocyanins makes it difficult to determine their effects on T2D. Understanding the absorption and metabolism of anthocyanins is important for understanding their role in the improvement of this disease. Published data suggest that anthocyanins may lower blood glucose by improving insulin resistance, protecting β cells, increasing secretion of insulin and reducing digestion of sugars in the small intestine. The mechanisms of action are primarily related to their antioxidant properties, but enzymatic inhibition and other pathways may also be relevant. © 2011 Elsevier Ltd.
dc.description46
dc.description1
dc.description378
dc.description386
dc.descriptionAdisakwattana, S., Charoenlertkul, P., Yibchok-Anun, S., A-Glucosidase inhibitory activity of cyanidin-3-galactoside and synergistic effect with acarbose (2009) Journal of Enzyme Inhibition and Medicinal Chemistry, 24, pp. 65-69
dc.descriptionAhrén, B., Type 2 diabetes, insulin secretion and β-cell mass (2005) Current Molecular Medicine, 5, pp. 275-286
dc.descriptionAmes, B.M., Shigena, M.K., Hagen, T.M., Oxidants, antioxidants and the degenerative diseases of aging (1993) Proceedings of the National Academy of Sciences U.S.A., 90, pp. 7915-7922
dc.descriptionAraki, E., Oyadomari, S., Mori, M., Endoplasmic reticulum stress and diabetes mellitus (2003) Internal Medicine, 42, pp. 7-14
dc.descriptionAtaie-Jafari, A., Hosseini, S., Karimi, F., Pajouhi, M., Effects of sour cherry juice on blood glucose and some cardiovascular risk factors improvements in diabetic women (2008) A pilot study. Nutrition & Food Science, 38, pp. 355-360
dc.descriptionAura, A.M., Martin-Lopez, P., O'Leary, K.A., Williamson, G., Oksman-Caldentey, K.M., Poutanen, K., Santos-Buelga, C., In vitro metabolism of anthocyanins by human gut microflora (2005) European Journal of Nutrition, 44, pp. 133-142
dc.descriptionAwika, J.M., Rooney, L.W., Waniska, R.D., Anthocyanins from black sorghum and their antioxidant properties (2005) Food Chemistry, 90, pp. 293-301
dc.descriptionBaron, A.D., Postprandial hyperglycaemia and α-glucosidase inhibitors (1998) Diabetes Research and Clinical Practice, 40, pp. S51-S55
dc.descriptionBasu, A., Wilkinson, M., Penugonda, K., Simmons, B., Betts, N.B., Timothy, J., Lyons, T.J., Freeze-dried strawberry powder improves lipid profile and lipid peroxidation in women with metabolic syndrome: Baseline and post intervention effects (2009) Nutrition Journal, 8, pp. 43-49
dc.descriptionBaynes, J.W., Thorpe, S.R., Perspectives in diabetes, role of oxidative stress in diabetic complications. A new perspective on an old paradigm (1999) Diabetes, 48, pp. 1-9
dc.descriptionBitsch, R., Netzel, N., Frank, T., Strass, G., Bitsch, I., Bioavailability and biokinetics of anthocyanins from red grape juice and red wine (2004) Journal of Biomedicine & Biotechnology, 5, pp. 293-298
dc.descriptionBonina, F.P., Leorra, C., Scalia, G., Puglia, C., Trombetta, D., Tringali, G., Roccazzello, A.M., Saija, A., Evaluation of oxidative stress in diabetic patients after supplementation with a standardised red orange extract (2002) Diabetes, Nutrition & Metabolism, 15, pp. 14-19
dc.descriptionBouwens, L., Rooman, I., Regulation of pancreatic betacell mass (2005) Physiological Reviews, 85, pp. 1255-1270
dc.descriptionBrouillard, R., Iacobucci, G.A., Sweeny, J.G., Chemistry of anthocyanin pigments. 9. UV-visible spectrophotometric determination of the acidity constants of apigeninidin and three related 3-deoxyflavylium salts (1982) Journal of the American Chemical Society, 104, pp. 7585-7590
dc.descriptionBryant, N.J., Govers, R., James, D.E., Regulated transport of the glucose transporter GLUT4 (2002) Nature Reviews. Molecular Cell Biology, 3, pp. 267-277
dc.descriptionBub, A., Watzl, B., Heeb, D., Rechkemmer, G., Briviba, K., Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice (2001) European Journal of Nutrition, 40, pp. 113-120
dc.descriptionCao, G.U., Muccitelli, H.U., Sánchez-Moreno, C., Prior, R.L., Anthocyanins are absorbed in glycated forms in elderly women: A pharmacokinetic study (2001) The American Journal of Clinical Nutrition, 73, pp. 920-926
dc.descriptionCevallos-Casals, B.A., Cisneros-Zevallos, L., Stability of anthocyanin-based aqueous extracts of Andean purple corn and red-fleshed sweet potato compared to synthetic and natural colorants (2004) Food Chemistry, 86, pp. 69-77
dc.descriptionChambers, B.K., Camire, M.H., Can cranberry supplementation benefit adults with type 2 diabetes? (2003) Diabetes Care, 26, pp. 2695-2696
dc.descriptionCharron, C.S., Kurilich, A.C., Beverly, A., Clevidence, B.A., Simon, P.W., Harrison, D.J., Britz, S.J., Novotny, J.A., Bioavailability of anthocyanins from purple carrot juice: effects of acylation and plant matrix (2009) Journal of Agricultural and Food Chemistry, 57, pp. 1226-1230
dc.descriptionChiasson, J.L., Josse, R.G., Gomis, R., Hanefeld, M., Karasik, A., Laakso, M., Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial (2002) The Lancet, 359, pp. 2072-2077
dc.descriptionClifford, M.N., Anthocyanins - nature, occurrence and dietary burden (2000) Journal of the Science of Food and Agriculture, 80, pp. 1063-1072
dc.descriptionDeFuria, J., Bennett, G., Strissel, K.J., Perfield, J.W., Milbury, P.E., Greenberg, A.S., Obin, M.S., Dietary blueberry attenuates whole-body insulin resistance in high hat-fed mice by reducing adipocyte death and its inflammatory sequelae (2009) The Journal of Nutrition, 139, pp. 1-7
dc.descriptionDel Bò, C., Ciappellano, S., Klimis-Zacas, D., Martini, D., Gardana, C., Riso, P., Porrini, M., Anthocyanin absorption, metabolism, and distribution from a wild blueberry-enriched diet (Vaccinium angustifolium) is affected by diet duration in the Sprague-Dawley rat (2010) Journal of Agricultural and Food Chemistry, 58, pp. 2491-2497
dc.descriptionDonath, M.Y., Sheolson, S.E., Type 2 diabetes as an inflammatory disease (2011) Nature Reviews Immunology, 11, pp. 98-107
dc.descriptionDonnelly, R., Emslie-Smith, A.M., Gardner, I.D., Morris, A.D., ABC of arterial and venous disease. Vascular complications of diabetes (2000) British Medical Journal, 320, pp. 1062-1066
dc.descriptionDresner, A., Laurent, D., Marcucci, M., Griffin, M.E., Dufour, S., Cline, G.W., Slezak, L.A., Rothman, D.L., Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity (1999) The Journal of Clinical Investigation, 103, pp. 253-259
dc.descriptionEhlenfeldt, M.K., Prior, R.L., Oxygen radical absorbance capacity (ORAC) and phenolic and anthocyanin concentrations in fruit and leaf tissues of highbush blueberry (2001) Journal of Agricultural and Food Chemistry, 49, pp. 2222-2227
dc.descriptionEvans, J.L., Goldfine, I.D., Maddux, B.A., Grodsky, G.M., Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction? (2003) Diabetes, 52, pp. 1-8
dc.descriptionFelgines, C., Talavera, S., Gonthier, M.P., Texier, O., Scalbert, A., Lamaison, J.L., Rémésy, C., Strawberry anthocyanins are recovered in urine as glucuro- and sulfoconjugates in humans (2003) The Journal of Nutrition, 133, pp. 1296-1301
dc.descriptionFelgines, C., Talavera, S., Texier, O., Gil-Izquierdo, A., Lamaison, J.L., Rémésy, C., Blackberry anthocyanins are mainly recovered from urine as methylated and glucuronidated conjugates in humans (2005) Journal of Agricultural and Food Chemistry, 53, pp. 7721-7727
dc.descriptionFeshani, A.M., Kouhsar, S.M., Mohammadi, S., Vaccinium arctostaphylos, a common herbal medicine in Iran: molecular and biochemical study of its antidiabetic effects on alloxan-diabetic Wistar rats (2011) Journal of Ethnopharmacology, 133, pp. 67-74
dc.descriptionForester, S.C., Waterhouse, A.L., Metabolites are key to understanding health effects of wine polyphenolics (2009) The Journal of Nutrition, 138, pp. 1824S-1831S
dc.descriptionForester, S.C., Waterhouse, A.L., Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells (2010) Journal of Agricultural and Food Chemistry, 58, pp. 5320-5327
dc.descriptionFuruta, M., Yano, Y., Gabazza, E.C., Araki-Sasaki, R., Tanaka, T., Katsuki, A., Hori, Y., Adachi, Y., Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus (2002) Diabetes Research and Clinical Practice, 56, pp. 159-171
dc.descriptionGrace, M.H., David, M., Ribnicky, D.M., Kuhnb, P., Poulev, A., Logendra, S., Yousef, G.G., Lila, M.A., Hypoglycemic activity of a novel anthocyanin-rich formulation from lowbush blueberry, Vaccinium angustifolium Aiton (2009) Phytomedicine, 16, pp. 406-415
dc.descriptionGray, G.M., Lally, B.C., Conklin, K.A., Action of intestinal sucrase-isomaltase and its free monomers on an α-limit dextrin (1979) The Journal of Biological Chemistry, 254, pp. 6038-6043
dc.descriptionGuo, H., Ling, W., Liu, C., Hu, Y., Xia, M., Feng, X., Xia, X., Effect of anthocyanin-rich extract from black rice (Oryza sativa L. indica) on hyperlipidemia and insulin resistance in fructose-fed rats (2007) Plant Foods for Human Nutrition, 62, pp. 1-6
dc.descriptionHe, J., Magnuson, B.A., Giusti, M.M., Analysis of anthocyanins in rat intestinal contents - Impact of anthocyanin chemical structure on fecal excretion (2005) Journal of Agricultural and Food Chemistry, 53, pp. 2859-2866
dc.descriptionHe, J., Giusti, M.M., Anthocyanins: natural colorants with health-promoting properties (2010) Annual Review of Food Science and Technology, 1, pp. 163-187
dc.descriptionHeinonen, I.M., Meyer, A.S., Frankel, E.N., Antioxidant activity of berry phenolics on human low-density lipoprotein and liposome oxidation (1998) Journal of Agricultural and Food Chemistry, 46, pp. 4107-4112
dc.descriptionHoustis, N., Rosen, E.D., Lander, E.S., Reactive oxygen species have a causal role in multiple forms of insulin resistance (2006) Nature, 440, pp. 944-948
dc.descriptionHunt, J.V., Smith, C.C., Wolff, S.P., Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose (1990) Diabetes, 39, pp. 1420-1424
dc.descriptionIchiyanagi, T., Rahman, M.M., Kashiwada, Y., Ikeshiro, Y., Shida, Y., Hatano, Y., Matsumoto, H., Konishi, T., Absorption and metabolism of delphinidin 3-O-β-d-glucopyranoside in rats (2004) Free Radical Biology & Medicine, 36, pp. 930-937
dc.descriptionIwai, K., Onodera, A., Matsue, H., Inhibitory effects of Viburnum dilatatum Thunb. (Gamazumi) on oxidation and hyperglycemia in rats with streptozotocin-induced diabetes (2004) Journal of Agricultural and Food Chemistry, 52, pp. 1002-1007
dc.descriptionJain, S.K., McVie, R., Duett, J., Herbst, J.J., Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes (1989) Diabetes, 38, pp. 1539-1543
dc.descriptionJayaprakasam, B., Vareed, S.K., Olson, L.K., Nair, M.G., Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits (2005) Journal of Agricultural and Food Chemistry, 53, pp. 28-31
dc.descriptionJayaprakasam, B., Olson, L.K., Schutzki, R.E., Tai, M.H., Nair, M.G., Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas) (2006) Journal of Agricultural and Food Chemistry, 54, pp. 243-248
dc.descriptionJurgoński, A., Juśkiewicz, J., Zduńczyk, Z., Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia (2008) Plant Foods for Human Nutrition, 63, pp. 176-182
dc.descriptionKähkönen, M.P., Heinonen, M., Antioxidant activity of anthocyanins and their aglycons (2003) Journal of Agricultural and Food Chemistry, 51, pp. 628-633
dc.descriptionKalt, W., Blumberg, J.B., McDonald, J.E., Vinqvist-Tymchuk, M.R., Fillmore, S.A.E., Graf, B.A., O'Leary, J.M., Milbury, P.E., Identification of anthocyanins in the liver, eye, and brain of blueberry-fed pigs (2008) Journal of Agricultural and Food Chemistry, 56, pp. 705-712
dc.descriptionKaneto, H., Fujii, J., Myint, T., Miyazawa, N., Islam, K.N., Kawasaki, K., Suzuki, K., Taniguchi, N., Reducing sugars trigger oxidative modification and apoptosis in pancreatic β-cells by provoking oxidative stress through the glycation reaction (1996) Biochemical Journal, 320, pp. 855-863
dc.descriptionKaneto, H., Kajimoto, Y., Miyagawa, J., Matsuoka, T., Fujitani, Y., Umayahara, Y., Hanafusa, T., Hori, M., Benefical effects of antioxidants in diabetes, possible protection of pancreatic β-cells against glucose toxicity (1999) Diabetes, 48, pp. 2398-2406
dc.descriptionKay, C.D., Holub, B.J., The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects (2002) British Journal of Nutrition, 88, pp. 389-397
dc.descriptionKay, C.D., Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans (2006) Nutrition Research Reviews, 19, pp. 137-146
dc.descriptionKelley, D.S., Rasooly, R., Jacob, R.A., Kader, A.A., Bruce, E., Mackey, B.E., Consumption of bing sweet cherries lowers circulating concentrations of inflammation markers in healthy men and women (2006) The Journal of Nutrition, 136, pp. 981-986
dc.descriptionKeppler, K., Humpf, H.U., Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora (2005) Bioorganic & Medicinal Chemistry, 13, pp. 5195-5205
dc.descriptionKong, J.M., Chia, L.S., Goh, N.K., Chia, T.F., Brouillard, R., Analysis and biological activities of anthocyanins (2003) Phytochemistry, 64, pp. 923-933
dc.descriptionLapidot, T., Harel, S., Akiri, B., Granit, R., Kanner, J., PH-dependent forms of red wine anthocyanins as antioxidants (1999) Journal of Agricultural and Food Chemistry, 47, pp. 67-70
dc.descriptionLeite, A.V., Malta, L.G., Riccio, M.F., Eberlin, M.N., Pastore, G.M., Maróstica Júnior, M.R., Antioxidant potential of rat plasma by administration of freeze-dried jaboticaba peel (Myrciaria jaboticaba Vell Berg) (2011) Journal of Agricultural and Food Chemistry, 59, pp. 2277-2283
dc.descriptionManach, C., Scalbert, A., Morand, C., Rémésy, C., Jiménez, L., Polyphenols: Food sources and bioavailability (2004) The American Journal of Clinical Nutrition, 79, pp. 727-747
dc.descriptionMartineau, L.C., Couture, A., Spoora, S., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Haddad, P.S., Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait (2006) Phytomedicine, 13, pp. 612-623
dc.descriptionMatsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., Matsumoto, K., α-Glucosidase inhibitory action of natural acylated anthocyanins. 1. Survey of natural pigments with potent inhibitory activity (2001) Journal of Agricultural and Food Chemistry, 49, pp. 1948-1951
dc.descriptionMatsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., Matsumoto, K., α-Glucosidase inhibitory action of natural acylated anthocyanins. 2. α-glucosidase inhibition by isolated acylated anthocyanins (2001) Journal of Agricultural and Food Chemistry, 49, pp. 1952-1956
dc.descriptionMatsui, T., Ebichi, S., Kobayashi, M., Fukui, K., Sugita, K., Terahara, N., Matsumoto, K., Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the α-glucosidase inhibitory action (2002) Journal of Agricultural and Food Chemistry, 50, pp. 7244-7248
dc.descriptionMatsuzawa, Y., Adipocytokines and metabolic syndrome (2005) Seminars in Vascular Medicine, 5, pp. 34-39
dc.descriptionMatuschek, M.C., Hendriks, W.H., McGhie, T.K., Reynolds, G.W., The jejunum is the main site of absorption for anthocyanins in mice (2006) The Journal of Nutritional Biochemistry, 17, pp. 31-36
dc.descriptionMazza, G., Brouillard, R., Recent developments in stabilization of anthocyanins in food products (1987) Food Chemistry, 25, pp. 207-225
dc.descriptionMazza, G., Kay, C.D., Cottrell, T., Holub, B.J., Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects (2002) Journal of Agricultural and Food Chemistry, 50, pp. 7731-7737
dc.descriptionMcDougall, G.J., Stewart, D., The inhibitory effects of berry polyphenols on digestive enzymes (2005) BioFactors, 23, pp. 189-195
dc.descriptionMcGhie, T.K., Ainge, G.D., Barnett, L.E., Cooney, J.M., Jensen, D.J., Anthocyanin glycosides from berry fruit are absorbed and excreted unmetabolised by both humans and rats (2003) Journal of Agricultural and Food Chemistry, 51, pp. 4539-4548
dc.descriptionMcGhie, T.K., Walton, M.C., The bioavailability and absorption of anthocyanins: Towards a better understanding (2007) Molecular Nutrition & Food Research, 51, pp. 702-713
dc.descriptionMoyer, R.A., Hummer, K.E., Finn, C.E., Frei, B., Wrolstad, R.E., Anthocyanins, phenolics, and antioxidant capacity in diverse small fruits: Vaccinium, Rubus, and Ribes (2002) Journal of Agricultural and Food Chemistry, 50, pp. 519-525
dc.descriptionNickavar, B., Amin, G., Anthocyanins from Vaccinium arctostaphylos berries (2004) Pharmaceutical Biology, 42, pp. 289-291
dc.descriptionNizamutdinova, I.T., Jin, Y.C., Chung, J., Shin, S.C., Lee, S.J., Seo, H.G., Lee, J.H., Kim, H.J., The anti-diabetic effect of anthocyanins in streptozotocin-induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and pancreatic apoptosis (2009) Molecular Nutrition & Food Research, 53, pp. 1419-1429
dc.descriptionNöthlings, U., Schulze, M.B., Weikert, C., Boeing, H., Schouw, Y.T., Bamia, C., Benetou, V., Trichopoulo, A., Intake of vegetables, legumes, and fruit, and risk for all-cause, cardiovascular, and cancer mortality in a European diabetic population (2008) The Journal of Nutrition, 138, pp. 775-781
dc.descriptionNurmi, T., Mursu, J., Heinonen, M., Nurmi, A., Hiltunen, R., Voutilainen, S., Metabolism of berry anthocyanins to phenolic acids in humans (2009) Journal of Agricultural and Food Chemistry, 57, pp. 2274-2281
dc.descriptionOhnishi, R., Ito, H., Kasajima, N., Kaneda, M., Kariyama, R., Kumon, H., Hatano, T., Yoshida, T., Urinary excretion of anthocyanins in humans after cranberry juice ingestion (2006) Bioscience, Biotechnology, and Biochemistry, 70, pp. 1681-1687
dc.descriptionPassamonti, S., Vrhovsek, U., Vanzo, A., Mattivi, F., The stomach as a site for anthocyanins absorption from food (2003) FEBS Letters, 544, pp. 210-213
dc.descriptionPhilpott, M., Gould, K.S., Lim, C., Ferguson, L.R., In situ and in vitro antioxidant activity of sweet potato anthocyanins (2004) Journal of Agricultural and Food Chemistry, 52, pp. 1511-1513
dc.descriptionPileggi, A., Molano, R.D., Berney, T., Cattan, P., Vizzardelli, C., Oliver, R., Fraker, C., Inverardi, L., Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation (2001) Diabetes, 50, pp. 1983-1991
dc.descriptionPrior, R.L., Cao, G., Martin, A., Sofic, E., McEwen, J., O'Brien, C., Lischner, N., Mainland, C.M., Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity, and variety of Vaccinium species (1998) Journal of Agricultural and Food Chemistry, 46, pp. 2686-2693
dc.descriptionPrior, R.L., Wu, X., Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities (2006) Free Radical Research, 40, pp. 1014-1028
dc.descriptionPrior, R.L., Wu, X., Gu, L., Hager, T., Hager, A., Wilkes, S., Howard, L., Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet (2009) Molecular Nutrition & Food Research, 53, pp. 1406-1418
dc.descriptionPrior, R.L., Wilkes, S.E., Rogers, T.R., Khanal, R.C., Wu, X., Howard, L.R., Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet (2010) Journal of Agricultural and Food Chemistry, 58, pp. 3970-3976
dc.descriptionRechner, A.R., Kuhnle, G., Bremner, P., Hubbard, G.P., Moore, K.P., Rice-Evans, C., The metabolic fate of dietary polyphenols in humans (2002) Free Radical Biology & Medicine, 33, pp. 220-235
dc.descriptionRoy, M., Sen, S., Chakraborti, A.S., Action of pelargonidin on hyperglycemia and oxidative damage in diabetic rats: Implication for glycation-induced hemoglobin modification (2008) Life Sciences, 82, pp. 1102-1110
dc.descriptionSartipy, P., Loskutoff, D.J., Monocyte chemoattractant protein 1 in obesity and insulin resistance (2003) Proceedings of the National Academy of Science of the USA, 100, pp. 7265-7270
dc.descriptionSasaki, R., Nishimura, N., Hoshino, H., Isa, Y., Kadowaki, M., Ichi, T., Tanaka, A., Tsuda, T., Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice (2007) Biochemical Pharmacology, 74, pp. 1619-1627
dc.descriptionSatué-Gracia, M.T., Heinonen, M., Frankel, E., Anthocyanins as antioxidants on human low-density lipoprotein and lecithin-liposome systems (1997) Journal of Agricultural and Food Chemistry, 45, pp. 3362-3367
dc.descriptionScalbert, A., Williamson, G., Dietary intake and bioavailability of polyphenols (2000) The Journal of Nutrition, 130, pp. 2073S-2085S
dc.descriptionSeeram, N., Berry fruits: Compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease (2008) Journal of Agricultural and Food Chemistry, 56, pp. 627-629
dc.descriptionSeymour, E.M., Singer, A.M.A., Kirakosyan, A., Urcuyo-Llanes, D.E., Kaufman, P.B., Bolling, S.F., Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry (2008) Journal of Medicinal Food, 11, pp. 252-259
dc.descriptionSeymour, E.M., Lewis, S.K., Urcuyo-Llanes, D.E., Tanone, I.I., Kirakosyan, A., Kaufman, P.B., Bolling, S.F., Regular tart cherry intake alters abdominal adiposity, adipose gene transcription, and inflammation in obesity-prone rats fed a high fat diet (2009) Journal of Medicinal Food, 12, pp. 935-942
dc.descriptionStintzing, F.C., Carle, R., Functional properties of anthocyanins and betalains in plants, food, and in human nutrition (2004) Trends in Food Science & Technology, 15, pp. 19-38
dc.descriptionStumvoll, M., Goldstein, B.J., van Haeften, T.W., Type 2 diabetes: Principles of pathogenesis and therapy (2005) The Lancet, 365, pp. 1333-1346
dc.descriptionSugimoto, E., Igarachi, K., Kubo, K., Molineux, J., Kubomura, K., Protective effects of boysenberry anthocyanins on oxidative stress in diabetic rats (2003) Food Science and Technology Research, 9, pp. 345-349
dc.descriptionTakikawa, M., Inoue, S., Horio, F., Tsuda, T., Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice (2010) The Journal of Nutrition, 140, pp. 527-533
dc.descriptionTalavéra, S., Felgines, C., Texier, O., Besson, C., Lamaison, J.L., Rémésy, C., Anthocyanins are efficiently absorbed from the stomach in anesthetized rats (2003) The Journal of Nutrition, 133, pp. 4178-4182
dc.descriptionTalavéra, S., Felgines, C., Texier, O., Besson, C., Manach, C., Lamaison, J.L., Rémésy, C., Anthocyanins are efficiently absorbed from the small intestine in rats (2004) The Journal of Nutrition, 134, pp. 2275-2279
dc.descriptionTian, Q., Giusti, M.M., Stoner, G.D., Schwartz, S.J., Urinary excretion of black raspberry (Rubus occidentalis) anthocyanins and their metabolites (2006) Journal of Agricultural and Food Chemistry, 54, pp. 1467-1472
dc.descriptionTiedge, M., Lortz, S., Drinkgern, J., Lenzen, S., Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells (1997) Diabetes, 46, pp. 1733-1742
dc.descriptionTourrel, C., Bailbe, D., Lacorne, M., Meile, M.J., Kergoart, M., Portha, B., Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4 (2002) Diabetes, 51, pp. 1443-1452
dc.descriptionTraustadóttir, T., Davies, S.S., Stock, A.A., Su, Y., Heward, C.B., Roberts, L.J., Harman, S.M., Tart cherry juice decreases oxidative stress in healthy older men and women (2009) The Journal of Nutrition, 139, pp. 1896-1900
dc.descriptionTsuda, T., Shiga, K., Ohshima, K., Kawakishi, S., Osawa, T., Inhibition of lipid peroxidation and the active oxygen radical scavenging effect of anthocyanin pigments isolated from Phaseolus vulgaris L (1996) Biochemical Pharmacology, 52, pp. 1033-1039
dc.descriptionTsuda, A., Horio, F., Osawa, T., Absorption and metabolism of cyanidin 3-O-l-d-glucoside in rats (1999) FEBS Letters, 449, pp. 179-182
dc.descriptionTsuda, T., Horio, F., Kitoh, J., Osawa, T., Protective effects of dietary cyanidin 3-O-beta-d-glucoside on liver ischemia-reperfusion injury in rats (1999) Archives of Biochemistry and Biophysics, 368, pp. 361-366
dc.descriptionTsuda, T., Horio, F., Uchida, K., Aoki, H., Osawa, T., Dietary cyanidin 3-O-beta-d-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice (2003) The Journal of Nutrition, 133, pp. 2125-2130
dc.descriptionTsuda, T., Ueno, Y., Kojo, H., Yoshikawa, T., Osawa, T., Gene expression profile of isolated rat adipocytes treated with anthocyanins (2005) Biochimica et Biophysica Acta, 1733, pp. 137-147
dc.descriptionVitaglione, P., Donnarumma, G., Napolitano, A., Galvano, F., Gallo, A., Scalfi, L., Fogliano, V., Protocatechuic acid is the major human metabolite of cyanidin-glucosides (2007) The Journal of Nutrition, 137, pp. 2043-2048
dc.descriptionWalle, T., Absorption and metabolism of flavonoids (2004) Free Radical Biology & Medicine, 36, pp. 829-837
dc.descriptionWang, D., Wei, X., Yan, X., Jin, T., Ling, A., Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice (2010) Journal of Agricultural and Food Chemistry, 58, pp. 12722-12728
dc.descriptionWeisel, T., Baum, M., Eisenbrand, G., Dietrich, H., Will, F., Stockis, J.P., Kulling, S., Christine Janzowski, C., An anthocyanin/polyphenolic-rich fruit juice reduces oxidative DNA damage and increases glutathione level in healthy probands (2006) Biotechnology Journal, 1, pp. 388-397
dc.descriptionWild, S., Roglic, G., Green, A., Sicree, R., King, H., Global prevalence of diabetes estimates for the year 2000 and projections for 2030 (2004) Diabetes Care, 27, pp. 1047-1053
dc.descriptionWoodward, G.M., Needs, P.W., Kay, C.D., Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation (2010) Molecular Nutrition & Food Research, 54, pp. 1-9
dc.descriptionWu, X., Cao, G., Prior, R.L., Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry (2002) The Journal of Nutrition, 132, pp. 1865-1871
dc.descriptionWu, X., Pittman, H.E., Mckay, S., Prior, R.L., Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs (2005) The Journal of Nutrition, 135, pp. 2417-2424
dc.descriptionXu, J.W., Ikeda, K., Yamori, Y., Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment (2004) Hypertension, 44, pp. 217-222
dc.descriptionYang, Q., Graham, T.E., Mody, N., Preitner, F., Peroni, O.D., Zabolotny, J.M., Kotani, K., Kahn, B.B., Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes (2005) Nature, 436, pp. 356-362
dc.descriptionYang, M.I., Koo, S.O., Song, W.K., Chun, O., Food matrix affecting anthocyanin bioavailability: Review (2011) Current Medicinal Chemistry, 18, pp. 291-300
dc.descriptionYi, W., Akoh, C.C., Foscher, J., Krewer, G., Absorption of anthocyanins from blueberry extracts by Caco-2 human intestinal cell monolayers (2006) Journal of Agricultural and Food Chemistry, 54, pp. 5651-5658
dc.descriptionZhang, B., Kang, M., Xie, Q., Xu, B., Sun, C., Chen, K., Wu, Y., Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulation (2011) Journal of Agricultural and Food Chemistry, 59, pp. 537-545
dc.languageen
dc.publisher
dc.relationFood Research International
dc.rightsfechado
dc.sourceScopus
dc.titleEvaluation Of The Effects Of Anthocyanins In Type 2 Diabetes
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución