dc.creatorSantos I.N.
dc.creatorSpadari-Bratfisch R.C.
dc.date2006
dc.date2015-06-30T18:14:32Z
dc.date2015-11-26T14:28:09Z
dc.date2015-06-30T18:14:32Z
dc.date2015-11-26T14:28:09Z
dc.date.accessioned2018-03-28T21:31:19Z
dc.date.available2018-03-28T21:31:19Z
dc.identifier
dc.identifierStress. , v. 9, n. 2, p. 69 - 84, 2006.
dc.identifier10253890
dc.identifier10.1080/10253890600771858
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-33747097832&partnerID=40&md5=e1260b67232fc9f123738275d8b455ce
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/103645
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/103645
dc.identifier2-s2.0-33747097832
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1246519
dc.descriptionMost modern theories about stress recognize that although stress is not a disease, it may be the trigger for the majority of diseases when allostatic overload has been generated. During stress, the glucocorticoids and catecholamines play a key role in the regulation of physiological parameters and homeostasis during stress. In the heart, positive chronotropic, inotropic, and lusitropic responses to catecholamines are mediated by various subtypes of adrenergic receptors (β-ARs), mainly β1- and β2 -adrenergic receptors. β-ARs also control cardiomyocyte growth and death, thus contributing to cardiac remodelling. The structural basis of each β-AR subtype, as well as their signalling pathways, and adaptive responses to stress are discussed. The participation of β3- and putative β4-ARs in the control of cardiac function is also discussed, with emphasis on low affinity β-AR isoforms and the role they play in the response to the catecholamines under stress. The changes in β-AR signalling under pathogenic conditions as well as under stress are reviewed. © 2006 Informa UK Ltd.
dc.description9
dc.description2
dc.description69
dc.description84
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dc.languageen
dc.publisher
dc.relationStress
dc.rightsfechado
dc.sourceScopus
dc.titleStress And Cardiac Beta Adrenoceptors
dc.typeArtículos de revistas


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