dc.creatorAntunes-Neto J.M.F.
dc.creatorToyama M.H.
dc.creatorCarneiro E.M.
dc.creatorBoschero A.C.
dc.creatorPereira-Da-Silva L.
dc.creatorMacedo D.V.
dc.date2006
dc.date2015-06-30T18:14:31Z
dc.date2015-11-26T14:28:07Z
dc.date2015-06-30T18:14:31Z
dc.date2015-11-26T14:28:07Z
dc.date.accessioned2018-03-28T21:31:18Z
dc.date.available2018-03-28T21:31:18Z
dc.identifier
dc.identifierStress. , v. 9, n. 2, p. 107 - 115, 2006.
dc.identifier10253890
dc.identifier10.1080/10253890600772211
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-33747085156&partnerID=40&md5=c10ad4cdf68826f12e6d84c9bdc4fb9f
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/103644
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/103644
dc.identifier2-s2.0-33747085156
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1246512
dc.descriptionA novel method to measure oxidative stress resulting from exhaustive exercise in rats is presented. In this new procedure we evaluated the erythrocyte antioxidant enzymes, catalase (CAT) and glutathione reductase (GR), the plasma oxidative attack markers, reactive carbonyl derivatives (RCD) and thiobarbituric reactive substances (TBARS). Muscular tissue damage was evaluated by monitoring plasma creatine kinase (CK) and plasma taurine (Tau) concentrations. Also, we monitored total sulphydryl groups (TSG) and uric acid (UA), and the level of the 70 kDa heat shock protein (HSP70) in leukocytes as a marker of oxidative stress. In the study we found a correspondence between erythrocyte CAT and GR activities and leukocyte HSP70 levels, principally 3 h after the acute exercise, and this suggested an integrated mechanism of antioxidant defense. The increase in levels of plasma Tau was coincident with the increasing plasma levels of CK and TBARS, principally after two hours of exercise. Thus tissue damage occurred before the expression of any anti-oxidant system markers and the monitoring of Tau, CK or TBARS may be important for the estimation of oxidative stress during exhaustive exercise. Furthermore, the integrated analyses could be of value in a clinical setting to quantify the extent of oxidative stress risk and reduce the need to perform muscle biopsies as a tool of clinical evaluation. © 2006 Informa UK Ltd.
dc.description9
dc.description2
dc.description107
dc.description115
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dc.languageen
dc.publisher
dc.relationStress
dc.rightsfechado
dc.sourceScopus
dc.titleCirculating Leukocyte Heat Shock Protein 70 (hsp70) And Oxidative Stress Markers In Rats After About Of Exhaustive Exercise
dc.typeArtículos de revistas


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