Fast Determination Of Basic Drugs In Plasma By Gas Chromatography With Nitrogen Phosphorus Detector [determinação Rápida De Fármacos Básicos Em Plasma Por Cromatografia A Gás Com Detector De Nitrogênio E Fósforo]

dc.creatorLizot L.F.
dc.creatorDa Silva L.L.
dc.creatorSpaniol B.
dc.creatorAntunes M.V.
dc.creatorLinden R.
dc.creatorLanaro R.
dc.date2012
dc.date2015-06-26T20:28:43Z
dc.date2015-11-26T14:24:34Z
dc.date2015-06-26T20:28:43Z
dc.date2015-11-26T14:24:34Z
dc.date.accessioned2018-03-28T21:26:49Z
dc.date.available2018-03-28T21:26:49Z
dc.identifier
dc.identifierQuimica Nova. , v. 35, n. 6, p. 1222 - 1227, 2012.
dc.identifier1004042
dc.identifier10.1590/S0100-40422012000600029
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84865276640&partnerID=40&md5=8eb8494ecfeccc16032e5b3475873f2b
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/96723
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/96723
dc.identifier2-s2.0-84865276640
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1245454
dc.descriptionA simple and fast method for determination of 40 basic drugs in human plasma employing gas-chromatography with nitrogen-phosphorus detection was developed and validated. Drugs were extracted from 800 ?L of plasma with 250 ?L of butyl acetate at basic pH. Aliquots of the organic extract were directly injected on a column with methylsilicone stationary phase. Total chromatographic run time was 25 min. All compounds were detected in concentrations ranging from therapeutic to toxic levels, with intermediate precision CV% below 11.2 and accuracy in the range of 92-114%.
dc.description35
dc.description6
dc.description1222
dc.description1227
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dc.languagept
dc.publisher
dc.relationQuimica Nova
dc.rightsaberto
dc.sourceScopus
dc.titleFast Determination Of Basic Drugs In Plasma By Gas Chromatography With Nitrogen Phosphorus Detector [determinação Rápida De Fármacos Básicos Em Plasma Por Cromatografia A Gás Com Detector De Nitrogênio E Fósforo]
dc.typeArtículos de revistas


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