Background: Fungal keratitis is an important cause of corneal infection mainly in tropical countries. With high morbidity due to delay in diagnosis, laboratory examination is mandatory in these cases. However, technical difficulties in obtaining samples generatea large number of false negatives. In these cases a detailed patient assessment for specific characteristics of this entity may help in diagnosis.Purpose: To create an epidemiological profile of patients with keratomycosis to assist in early diagnosis and treatment.Methods: A retrospective study was performed by searching patients with keratomycosis diagnostic on the corneal ulcers database. Information about gender, household location, educational level, occupation, age, predisposing and precipitating factors (ocular and systemic), initial etiological hypothesis, laboratory results, healing time, complications, and adjuvant treatments were collected.Results: Of 599 patients with corneal ulcer, 150(25%) were diagnosed as fungal infection. There was a higher prevalence in males of working age and low educational level. Trauma with plant material was involved in 74 (49.33%) cases. Other factors such as workers and residents of rural areas also supports trauma withvegetalas the main risk factor identified in the study.Conclusions: Based on the collected data, it was possible to form a profile of patients with fungal ulcers treated by HC-UNICAMP.754247250Wilhelmus, K., Epidemiology of ocular infections (1998) Tasman W JE, editor. Foundations of Clinical Ophthalmology, , Philadelphia: Lippincott-RavenBharathi, M.J., Ramakrishnan, R., Meenakshi, R., Shivakumar, C., Raj, D.L., Analysis of the risk factors predisposing to fungal, bacterial & acanthamoeba keratitis in south India (2009) Indian J Med Res., 130 (6), pp. 749-757Rippon, J., Medical Mycology (1988) The Pathogenic Fungi and the Pathogenic Actinomycetes, , Philadelphia: Saunders CoHöfling-Lima, A.L., Forseto, A., Duprat, J.P., Andrade, A., Souza, L.B.D., Godoy, P., Estudo laboratorial das micoses oculares e fatores associados às ceratites (2005) Arq Bras Oftalmol., 68 (1), pp. 21-27Kurokawa, C.S., Sugizaki, M.F., Peracoli, M.T., Virulence factors in fungi of systemic mycoses (1998) Rev Inst Med Trop Sao Paulo., 40 (3), pp. 125-135Wong, T.Y., Ng, T.P., Fong, K.S., Tan, D.T., Risk factors and clinical outcomes between fungal and bacterial keratitis: a comparative study (1997) CLAO J., 23 (4), pp. 275-281Oliveira, P.R., Resende, S.M., Oliveira, F.C., Oliveira, A.C., Ceratite fúngica (2001) Arq Bras Oftalmol., 64 (1), pp. 75-79Allan, B.D., Dart, J.K., Strategies for the management of microbial keratitis (1995) Br J Ophthalmol., 79 (8), pp. 777-786Kumar, M., Shukla, P.K., Use of PCR targeting of internal transcribed spacer regions and single-stranded conformation polymorphism analysis of sequence variation in different regions of rrna genes in fungi for rapid diagnosis of mycotic keratitis (2005) J Clin Microbiol., 43 (2), pp. 662-668Dunlop, A.A., Wright, E.D., Howlader, S.A., Nazrul, I., Husain, R., Mcclellan, K., Suppurative corneal ulceration in Bangladesh (1994) A study of 142 cases examining the microbiological diagnosis, clinical and epidemiological features of bacterial and fungal keratitis. Aust N Z J Ophthalmol., 22 (2), pp. 105-110Jones, D., Diagnosis and management of fungal keratitis (2005) Duane's clinical ophthalmology. 5th ed., , Philadelphia: Lippincott Williams & WilkinsAlfonso, E.C.G.A., Miller, D., Fungal keratitis (2010) Krachmer JH MM, Holland EJ, editor, , Cornea: fundamentals, diagnosis and management. 3th ed. New York: Mosby ElsevierIbrahim, M.M., Vanini, R., Ibrahim, F.M., Martins, W.D.P., Carvalho, R.T., Castro, R.S., Rocha, E.M., Epidemiology and medical prediction of microbial keratitis in southeast Brazil (2011) Arq Bras Oftalmol., 74 (1), pp. 7-12Vanzzini Zago, V., Manzano-Gayosso, P., Hernández-Hernández, F., Méndez-Tovar, L.J., Gómez-Leal, A., López Martínez, R., Mycotic keratitis in an eye care hospital in Mexico City (2010) Rev Iberoam Micol, 27 (2), pp. 57-61. , Spanish(2010) Distribuição percentual da população nos Censos Demográficos, segundo as Grandes Regiões, as Unidades da Federação e a situação do domicílio - 1960/2010, , http://www.ibge.gov.br/home/estatistica/populacao/censo2010/tabelas_pdf/ Brasil_tab_1_9.pdf, IBGE, Available fromGopinathan, U., Garg, P., Fernandes, M., Sharma, S., Athmanathan, S., Rao, G.N., The epidemiological features and laboratory results of fungal keratitis: a 10-year review at a referral eye care center in South India (2002) Cornea, 21 (6), pp. 555-559Costa, M.L.G.P., Lage, J., Flora micótica da conjuntiva de indivíduos normais (1975) Rev Bras Oftalmol., 34 (2), pp. 199-206Bharathi, M.J., Ramakrishnan, R., Vasu, S., Meenakshi, R., Palaniappan, R., Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study (2003) Indian J Ophthalmol., 51 (4), pp. 315-321Xie, L., Zhong, W., Shi, W., Sun, S., Spectrum of fungal keratitis in north China (2006) Ophthalmology, 113 (11), pp. 1943-1948Andrade, A.J., Vieira, L.A., Höfling-Lima, A.L., Yu, M.C., Gompertz, O.F., Freitas, D., Laboratorial analyses of fungal keratitis in a University Service (2000) Arq Bras Oftalmol., 63 (1), pp. 59-63Green, M., Apel, A., Stapleton, F., Risk factors and causative organisms in microbial keratitis (2008) Cornea, 27 (1), pp. 22-27Saha, S., Banerjee, D., Khetan, A., Sengupta, J., Epidemiological profile of fungal keratitis in urban population of West Bengal, India (2009) Oman J Ophthalmol., 2 (3), pp. 114-118Alexandrakis, G., Haimovici, R., Miller, D., Alfonso, E.C., Corneal biopsy in the management of progressive microbial keratitis (2000) Am J Ophthalmol., 129 (5), pp. 571-576Ishibashi, Y., Hommura, S., Matsumoto, Y., Direct examination vs culture of biopsy specimens for the diagnosis of keratomycosis (1987) Am J Ophthalmol., 103 (5), pp. 636-640Rosa Jr., R.H., Miller, D., Alfonso, E.C., The changing spectrum of fungal keratitis in south Florida (1994) Ophthalmology, 101 (6), pp. 1005-1013Salera, C.M., Tanure, M.A., Lima, W.T., Campos, C.M., Trindade, F.C., Moreira, J.A., Perfil das ceratites fúngicas no Hospital São Geraldo Belo Horizonte - MG (2002) Arq Bras Oftalmol., 65 (1), pp. 9-13