Long-term Postoperative Atrophy Of Contralateral Hippocampus And Cognitive Function In Unilateral Refractory Mtle With Unilateral Hippocampal Sclerosis

dc.creatorFernandes D.A.
dc.creatorYasuda C.L.
dc.creatorLopes T.M.
dc.creatorEnrico G.
dc.creatorAlessio A.
dc.creatorTedeschi H.
dc.creatorde Oliveira E.
dc.creatorCendes F.
dc.date2014
dc.date2015-06-25T17:53:02Z
dc.date2015-11-26T14:21:15Z
dc.date2015-06-25T17:53:02Z
dc.date2015-11-26T14:21:15Z
dc.date.accessioned2018-03-28T21:22:59Z
dc.date.available2018-03-28T21:22:59Z
dc.identifier
dc.identifierEpilepsy And Behavior. Academic Press Inc., v. 36, n. , p. 108 - 114, 2014.
dc.identifier15255050
dc.identifier10.1016/j.yebeh.2014.04.028
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84901762722&partnerID=40&md5=f1e76203afe364e5dfaa0fc9dc678c87
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/86373
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/86373
dc.identifier2-s2.0-84901762722
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1244475
dc.descriptionObjective: This study aimed to evaluate long-term atrophy in contralateral hippocampal volume after surgery for unilateral MTLE, as well as the cognitive outcome for patients submitted to either selective transsylvian amygdalohippocampectomy (SelAH) or anterior temporal lobe resection (ATL). Methods: We performed a longitudinal study of 47 patients with MRI signs of unilateral hippocampal sclerosis (23 patients with right-sided hippocampal sclerosis) who underwent surgical treatment for MTLE. They underwent preoperative/postoperative high-resolution MRI as well as neuropsychological assessment for memory and estimated IQ. To investigate possible changes in the contralateral hippocampus of patients, we included 28 controls who underwent two MRIs at long-term intervals. Results: The volumetry using preoperative MRI showed significant hippocampal atrophy ipsilateral to the side of surgery when compared with controls (p. <. 0.0001) but no differences in contralateral hippocampal volumes. The mean postoperative follow-up was 8.7. years (±. 2.5 SD; median = 8.0). Our patients were classified as Engel I (80%), Engel II (18.2%), and Engel III (1.8%). We observed a small but significant reduction in the contralateral hippocampus of patients but no volume changes in controls. Most of the patients presented small declines in both estimated IQ and memory, which were more pronounced in patients with left TLE and in those with persistent seizures. Different surgical approaches did not impose differences in seizure control or in cognitive outcome. Conclusions: We observed small declines in cognitive scores with most of these patients, which were worse in patients with left-sided resection and in those who continued to suffer from postoperative seizures. We also demonstrated that manual volumetry can reveal a reduction in volume in the contralateral hippocampus, although this change was mild and could not be detected by visual analysis. These new findings suggest that dynamic processes continue to act after the removal of the hippocampus, and further studies with larger groups may help in understanding the underlying mechanisms. © 2014 Elsevier Inc.
dc.description36
dc.description
dc.description108
dc.description114
dc.descriptionHauser, W.A., Annegers, J.F., Rocca, W.A., Descriptive epidemiology of epilepsy - contributions of population-based studies from Rochester, Minnesota (1996) Mayo Clinic Proceedings, 71, pp. 576-586
dc.descriptionYasuda, C.L., Tedeschi, H., Oliveira, E.L., Ribas, G.C., Costa, A.L., Cardoso, T.A., Comparison of short-term outcome between surgical and clinical treatment in temporal lobe epilepsy: a prospective study (2006) Seizure, 15, pp. 35-40. , [S1059-1311(05)00209-8 [pii]]
dc.descriptionWiebe, S., Blume, W.T., Girvin, J.P., Eliasziw, M., A randomized, controlled trial of surgery for temporal-lobe epilepsy (2001) N Engl J Med, 345, pp. 311-318
dc.descriptionHelmstaedter, C., Neuropsychological aspects of epilepsy surgery (2004) Epilepsy Behav, 5 (SUPPL. 1), pp. S45-S55. , [S1525505003003196 [pii]]
dc.descriptionSherman, E.M., Wiebe, S., Fay-McClymont, T.B., Tellez-Zenteno, J., Metcalfe, A., Hernandez-Ronquillo, L., Neuropsychological outcomes after epilepsy surgery: systematic review and pooled estimates (2011) Epilepsia, 52, pp. 857-869
dc.descriptionAndersson-Roswall, L., Engman, E., Samuelsson, H., Malmgren, K., Cognitive outcome 10years after temporal lobe epilepsy surgery: a prospective controlled study (2010) Neurology, 74, pp. 1977-1985. , [74/24/1977 [pii]]
dc.descriptionBaxendale, S., Thompson, P.J., Duncan, J.S., Neuropsychological function in patients who have had epilepsy surgery: a long-term follow-up (2012) Epilepsy Behav, 23, pp. 24-29. , [S1525-5050(11)00619-6 [pii]]
dc.descriptionHelmstaedter, C., Kurthen, M., Lux, S., Reuber, M., Elger, C.E., Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy (2003) Ann Neurol, 54, pp. 425-432
dc.descriptionGrammaldo, L.G., Di Gennaro, G., Giampà, T., De Risi, M., Meldolesi, G.N., Mascia, A., Memory outcome 2 years after anterior temporal lobectomy in patients with drug-resistant epilepsy (2009) Seizure, 18 (2), pp. 139-144
dc.descriptionKuang, Y., Yang, T., Gu, J., Kong, B., Cheng, L., Comparison of therapeutic effects between selective amygdalohippocampectomy and anterior temporal lobectomy for the treatment of temporal lobe epilepsy: A meta-analysis (2013) Br J Neurosurg., 7, pp. 1-4
dc.descriptionTanriverdi, T., Olivier, A., Poulin, N., Andermann, F., Dubeau, F., Long-term seizure outcome after mesial temporal lobe epilepsy surgery: corticalamygdalohippocampectomy versus selective amygdalohippocampectomy (2008) J Neurosurg, 108, pp. 517-524
dc.descriptionvon, R.B., Nelles, M., Urbach, H., von, L.M., Schramm, J., Helmstaedter, C., Neuropsychological outcome after selective amygdalohippocampectomy: subtemporal versus transsylvian approach (2012) J Neurol Neurosurg Psychiatry, 83, pp. 887-893. , [jnnp-2011-302025 [pii]]
dc.descriptionBaxendale, S., Thompson, P.J., Duncan, J.S., Neuropsychological function in patients who have had epilepsy surgery: a long-term follow-up (2011) Epilepsy Behav, , [S1525-5050(11)00619-6 [pii]]
dc.descriptionChapin, J.S., Busch, R.M., Silveira, D.C., Wehner, T., Naugle, R.I., Ferguson, L., Memory performance in older adults before and after temporal lobectomy for pharmacoresistant epilepsy (2013) Clin Neuropsychol, 27, pp. 1316-1327
dc.descriptionEngel, J., A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology (2001) Epilepsia, 42, pp. 796-803. , [epi10401 [pii]]
dc.descriptionYasuda, C.L., Valise, C., Saude, A.V., Pereira, A.R., Pereira, F.R., Ferreira Costa, A.L., Dynamic changes in white and gray matter volume are associated with outcome of surgical treatment in temporal lobe epilepsy (2010) Neuroimage, 49, pp. 71-79. , [S1053-8119(09)00891-X [pii]]
dc.descriptionBonilha, L., Kobayashi, E., Cendes, F., Min, L.L., Protocol for volumetric segmentation of medial temporal structures using high-resolution 3-D magnetic resonance imaging (2004) Hum Brain Mapp, 22, pp. 145-154
dc.descriptionStrauss, E., Sherman, E.M.S., Spreen, O., (2006) A compendium of neuropsychological test, , OXFORD University Press, New York
dc.descriptionMalloy-Diniz, L.F., Lasmar, V.A., Gazinelli, L.S., Fuentes, D., Salgado, J.V., The Rey Auditory-Verbal Learning Test: applicability for the Brazilian elderly population (2007) Rev Bras Psiquiatr, 29, pp. 324-329. , [S1516-44462006005000053 [pii]]
dc.descriptionde, T.J., Bell, G.S., Peacock, J.L., McEvoy, A.W., Harkness, W.F., Sander, J.W., The long-term outcome of adult epilepsy surgery, patterns of seizure remission, and relapse: a cohort study (2011) Lancet, 378, pp. 1388-1395. , [S0140-6736(11)60890-8 [pii]]
dc.descriptionNoulhiane, M., Samson, S., Clemenceau, S., Dormont, D., Baulac, M., Hasboun, D., A volumetric MRI study of the hippocampus and the parahippocampal region after unilateral medial temporal lobe resection (2006) J Neurosci Methods, 156, pp. 293-304. , [S0165-0270(06)00135-X [pii]]
dc.descriptionBonilha, L., Edwards, J.C., Kinsman, S.L., Morgan, P.S., Fridriksson, J., Rorden, C., Extrahippocampal gray matter loss and hippocampal deafferentation in patients with temporal lobe epilepsy (2010) Epilepsia, 51, pp. 519-528. , [EPI2506 [pii]]
dc.descriptionAndersson, D., Wilhelmsson, U., Nilsson, M., Kubista, M., Stahlberg, A., Pekna, M., Plasticity response in the contralesional hemisphere after subtle neurotrauma: gene expression profiling after partial deafferentation of the hippocampus (2013) PLoS One, 8, pp. e70699. , [PONE-D-13-15506 [pii]]
dc.descriptionBaxendale, S., The impact of epilepsy surgery on cognition and behavior (2008) Epilepsy Behav, 12, pp. 592-599. , [S1525-5050(07)00479-9 [pii]]
dc.descriptionRausch, R., Kraemer, S., Pietras, C.J., Le, M., Vickrey, B.G., Passaro, E.A., Early and late cognitive changes following temporal lobe surgery for epilepsy (2003) Neurology, 60, pp. 951-959
dc.descriptionAlpherts, W.C., Vermeulen, J., van Rijen, P.C., da Silva, F.H., van Veelen, C.W., Verbal memory decline after temporal epilepsy surgery?: a 6-year multiple assessments follow-up study (2006) Neurology, 67, pp. 626-631. , [67/4/626 [pii]]
dc.descriptionSattler, J.M., (1988) Assessment of children, p. 995. , Jerome M. Sattler, Publisher, San Diego
dc.descriptionHelmstaedter, C., Cognitive outcomes of different surgical approaches in temporal lobe epilepsy (2013) Epileptic Disord, 15, pp. 221-239. , [epd.2013.0587 [pii]]
dc.descriptionPaglioli, E., Palmini, A., Portuguez, M., Paglioli, E., Azambuja, N., da Costa, J.C., Seizure and memory outcome following temporal lobe surgery: selective compared with nonselective approaches for hippocampal sclerosis (2006) J Neurosurg, 104, pp. 70-78
dc.descriptionClusmann, H., Schramm, J., Kral, T., Helmstaedter, C., Ostertun, B., Fimmers, R., Prognostic factors and outcome after different types of resection for temporal lobe epilepsy (2002) J Neurosurg, 97, pp. 1131-1141
dc.descriptionHelmstaedter, C., Richter, S., Roske, S., Oltmanns, F., Schramm, J., Lehmann, T.N., Differential effects of temporal pole resection with amygdalohippocampectomy versus selective amygdalohippocampectomy on material-specific memory in patients with mesial temporal lobe epilepsy (2008) Epilepsia, 49, pp. 88-97. , [EPI1386 [pii]]
dc.descriptionSagher, O., Thawani, J.P., Etame, A.B., Gomez-Hassan, D.M., Seizure outcomes and mesial resection volumes following selective amygdalohippocampectomy and temporal lobectomy (2012) Neurosurg Focus, 32, pp. E8
dc.languageen
dc.publisherAcademic Press Inc.
dc.relationEpilepsy and Behavior
dc.rightsfechado
dc.sourceScopus
dc.titleLong-term Postoperative Atrophy Of Contralateral Hippocampus And Cognitive Function In Unilateral Refractory Mtle With Unilateral Hippocampal Sclerosis
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución