Insulin Receptor/irs-1/pi 3-kinase Signaling System In Corticosteroid-induced Insulin Resistance

dc.creatorFolli F.
dc.creatorSaad M.J.A.
dc.creatorKahn C.R.
dc.date1996
dc.date2015-06-26T17:03:16Z
dc.date2015-11-26T14:18:50Z
dc.date2015-06-26T17:03:16Z
dc.date2015-11-26T14:18:50Z
dc.date.accessioned2018-03-28T21:20:12Z
dc.date.available2018-03-28T21:20:12Z
dc.identifier
dc.identifierActa Diabetologica. , v. 33, n. 3, p. 185 - 192, 1996.
dc.identifier9405429
dc.identifier10.1007/s005920050032
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0029914756&partnerID=40&md5=5e40ad3dfaa138e82cc50142f01d94bf
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/95572
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/95572
dc.identifier2-s2.0-0029914756
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1243758
dc.description[No abstract available]
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dc.description3
dc.description185
dc.description192
dc.descriptionFelig, P., Bergman, M., Integrated physiology of carbohydrate metabolism (1990) Ellenberg and Rifkin's Diabetes Mellitus, , Rifkin H, Porte D (eds) Elsevier, New York
dc.descriptionKahn, C.R., White, M.F., Shoelson, S.E., The insulin receptor and its substrate: Molecular determinants of early events in insulin action (1993) Recent Progress in Hormone Research, 48, pp. 291-339. , Academic Press, London
dc.descriptionGammeltofi, S., Kahn, C.R., Hormone signaling via membrane receptors (1995) Endocrinology, pp. 17-65. , DeGroot LJ, Besser M, Burger HG et al. (eds) W.B. Saunders, Philadelphia
dc.descriptionCheatham, B., Kahn, C.R., Insulin action and the insulin signaling network (1995) Endocrinol Rev, 16, pp. 117-142
dc.descriptionFreychet, P., Roth, J., Neville Jr., D.M., Insulin receptors in the liver, specific binding of [125I] insulin to the plasma membrane and its relation to insulin bioactivity (1971) Proc Natl Acad Sci USA, 68, pp. 1833-1837
dc.descriptionCuatrecasas, P., Affinity chromatography and purification of the insulin receptor of liver cell membranes (1972) Proc Natl Acad Sci USA, 69, pp. 1277-1281
dc.descriptionMassague, J., Pilch, P.F., Czech, M.P., Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries (1981) Proc Natl Acad Sci USA, 77, pp. 7137-7141
dc.descriptionKasuga, M., Hedo, J.A., Yamada, K.M., Kahn, C.R., The structure of the insulin receptor and its subunits: Evidence for multiple non-reduced forms and a 210K possible proreceptor (1982) J Biol Chem, 257, pp. 10392-10399
dc.descriptionUllrich, A., Bell, J.R., Chen, E.Y., Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes (1985) Nature, 313, pp. 756-761
dc.descriptionEbina, Y., Ellis, L., Jarnagin, K., The human insulin receptor cDNA: The structural basis for hormone activated transmembrane signalling (1985) Cell, 40, pp. 747-758
dc.descriptionSeino, S., Seino, M., Nishi, S., Bell, G.I., Structure of the human insulin receptor gene and characterization of its promoter (1989) Proc Natl Acad Sci USA, 86, pp. 114-118
dc.descriptionGoldstein, B.J., Muller-Wieland, D., Kahn, C.R., Variation in insulin receptor mRNA expression in human and rodent tissues (1987) Mol Endocrinol, 1, pp. 759-766
dc.descriptionSell, S.M., Reese, D., Ossowski, V.M., Insulin-inducible changes in insulin receptor mRNA splice variants (1994) J Biol Chem, 269, pp. 30769-30772
dc.descriptionKellerer, M., Sesti, G., Seffer, E., Ullrich, A., Haring, H.U., Altered pattern of insulin receptor isotypes in skeletal muscle membranes of NIDDM patients (1993) Diabetologia, 36, pp. 628-632
dc.descriptionNorgren, S., Zierath, J., Galuska, D., Wallberg-Henriksson, H., Luthman, H., Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. the RNA variant without exon 11 predominates in both groups (1993) Diabetes, 42, pp. 675-681
dc.descriptionBenecke, H., Flier, J.S., Moller, D.E., Alternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissues (1992) J Clin Invest, 8966, pp. 2066-2070
dc.descriptionHansen, T., Bjorbaek, C., Vestergaard, H., Gronskov, K., Bak, J.F., Pedersen, O., Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus (1993) J Clin Endocrinol Meta, 77, pp. 1500-1505
dc.descriptionDe Mcyts, P., Gu, J.L., Shymko, R.M., Kaplan, B.E., Bell, G.I., Whittaker, J., Identification of a ligand-binding region of the human insulin receptor encoded by the second exon of the gene (1990) Mol Endocrinol, 4, pp. 409-416
dc.descriptionKasuga, M., Karlsson, F.A., Kahn, C.R., Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor (1982) Science, 215, pp. 185-187
dc.descriptionWhite, M.F., Haring, H.U., Kasuga, M., Kahn, C.R., Kinetic properties and sites of autophosphorylation in the partially purified insulin receptor from hepatoma cells (1984) J Biol Chem, 259, pp. 255-264
dc.descriptionWhite, M.F., Shoelson, S.E., Keutmann, H., Kahn, C.R., A cascade of tyrosine autophosphorylation in the β-subunit activates the insulin receptor (1988) J Biol Chem, 263, pp. 2969-2980
dc.descriptionYu, K.T., Czech, M.P., Tyrosine phosphorylation of the insulin receptor β subunit activates the receptor-associated tyrosine kinase activity (1984) J Biol Chem, 259, pp. 5277-5286
dc.descriptionEllis, L., Clauser, E., Morgan, D.O., Edery, M., Roth, R.A., Rutter, W.J., Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose (1986) Cell, 45, pp. 721-732
dc.descriptionWilden, P.A., Siddle, K., Haring, E., Backer, J.M., White, M.F., Kahn, C.R., The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities (1992) J Biol Chem, 267, pp. 13719-13727
dc.descriptionKasuga, M., Zick, Y., Blithe, D.L., Karlsson, F.A., Haring, H.U., Kahn, C.R., Insulin stimulation of phosphorylation of the β-subunit of the insulin receptor: Formation of both phosphoserine and phosphotyrosine (1982) J Biol Chem, 257, pp. 9891-9894
dc.descriptionTakayama, S., White, M.F., Lauris, V., Kahn, C.R., Phorbol esters modulate insulin receptor phosphorylation and insulin action in hepatoma cells (1984) Proc Natl Acad Sci USA, 81, pp. 7797-7801
dc.descriptionTakayama, S., White, M.F., Kahn, C.R., Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity (1988) J Biol Chem, 263, pp. 3440-3447
dc.descriptionEbina, Y., Araki, E., Taira, M., Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity (1987) Proc Natl Acad Sci USA, 84, pp. 704-708
dc.descriptionPawson, T., Protein modules and signalling networks (1995) Nature, 373, pp. 573-580
dc.descriptionWhite, M.F., Maron, R., Kahn, C.R., Insulin rapidly stimulates tyrosine phosphorylation of a Mr 185,000 protein in intact cells (1985) Nature, 318, pp. 183-186
dc.descriptionSun, X., Miralpeix, M., Myers Jr., M.G., The expression and function of IRS-1 in insulin signal transmission (1992) J Biol Chem, 267, pp. 22662-22672
dc.descriptionWhite, M.F., Livingstone, J.N., Backer, J.M., Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity (1988) Cell, 54, pp. 651-1649
dc.descriptionRothenberg, P.L., Lane, W.S., Karasik, A., Backer, J., White, M., Kahn, C.R., Purification and partial sequence analysis of pp 185, the major cellular substrate of the insulin receptor tyrosine kinase (1991) J Biol Chem, 266, pp. 8302-8311
dc.descriptionSun, X., Rothenberg, P., Kahn, C.R., The structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein (1991) Nature, 352, pp. 73-77
dc.descriptionAraki, E., Sun, X., Haag, B.L., Human skeletal muscle insulin receptor substrate-1: Characterization of the cDNA, gene and chromosomal localization (1993) Diabetes, 42, pp. 1041-1054
dc.descriptionWhite, M.F., Kahn, C.R., The insulin signaling system (1994) J Biol Chem, 269, pp. 1-5
dc.descriptionBacker, J.M., Schroeder, G.G., Kahn, C.R., Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation (1992) J Biol Chem, 267, pp. 1367-1374
dc.descriptionBacker, J.M., Myers Jr., M.G., Shoelson, S.E., The phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation (1992) EMBO J, 11, pp. 3469-3479
dc.descriptionFolli, F., Saad, M.J.A., Backer, J.M., Kahn, C.R., Insulin stimulation of phosphatidyhnositol 3-kinase activity and association with IRS-1 in liver and muscle of the intact rat (1992) J Biol Chem, 267, pp. 22171-22177
dc.descriptionHadari, Y.R., Tzahar, E., Nadiv, O., Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers (1993) J Biol Chem, 268, p. 9156
dc.descriptionWhitman, M., Downes, C.P., Keeler, M., Keller, T., Cantley, L., Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate (1988) Nature, 332, pp. 644-646
dc.descriptionHiles, I.D., Otsu, M., Volinna, S., Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit (1992) Cell, 70, pp. 419-429
dc.descriptionHerman, P.K., Emr, S.D., Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae (1990) Mol Cell Biol, 12, pp. 981-990
dc.descriptionEscobedo, J.A., Navankasattusas, S., Kavanaugh, W.M., Milfay, D., Fried, V.A., Williams, L.T., cDNA cloning of a novel 85 kD protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor (1991) Cell, 65, pp. 75-82
dc.descriptionCarpenter, C.L., Cantley, L.C., Phosphoinositide kinases (1990) Biochemistry, 29, pp. 11147-11156
dc.descriptionCheatham, B., Vlahos, C.J., Cheatham, L., Wang, L., Blenis, J., Kahn, C.R., Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation (1994) Mol Cell Biol, 14, pp. 4902-4911
dc.descriptionOkada, T., Kawano, Y., Sakakibara, T., Hazeki, O., Ui, M., Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes (1994) J Biochem, 269, pp. 3568-3573
dc.descriptionBlenis, J., Chung, J., Erikson, E., Alcorta, D.A., Erikson, R.L., Distinct mechanisms for the activation of the RSK kinases/MAP2 kinase/pp90rsk and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis (1991) Cell Growth Diff, 2, pp. 279-285
dc.descriptionKuhne, M.R., Pawson, T., Lienhard, G.E., Feng, G.-S., The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp (1993) J Biol Chem, 268, pp. 11479-11481
dc.descriptionTobe, K., Matuoka, K., Tamemoto, H., Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2 (1993) J Biol Chem, 268, pp. 11167-11171
dc.descriptionSun, X., Crimmins, D.L., Myers Jr., M.G., Miralpeix, M., White, M.F., Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 (1993) Mol Cell Biol, 13, pp. 7418-7428
dc.descriptionSun, X., Wang, L.M., Zhang, Y., The structure and function of 4PS reveals IRS-2: A common interface in insulin and cytokine signaling (1995) Nature, 377, pp. 173-177
dc.descriptionWang, L.M., Myers Jr., M.G., Sun, X., Aaronson, S.A., White, M.F., Pierce, J.H., IRS-1: Essential for insulin and IL-4-stimulated mitogenesis in hematopoietic cells (1993) Science, 261, pp. 1591-1594
dc.descriptionPatti, M.E., Sun, X., Bruning, J.C., 4PS/IRS-2 is the alternative substrate of the insulin receptor in IRS-1 deficient mice (1995) J Biol Chem, 270, pp. 24670-24673
dc.descriptionFolli, F., Bonfanti, L., Renard, E., Kahn, C.R., Merighi, A., Insulin receptor substrate-1 (IRS-1) distribution in the rat central nervous system (1994) J Neurosci, 14, pp. 6412-6422
dc.descriptionBergman, R.N., Finegold, D.T., Ader, M., Assessment of insulin sensitivity in vivo (1985) Endocr Rev, 6, pp. 45-86
dc.descriptionReynet, C., Kahn, C.R., Rad: A member of the ras family overexpressed in muscle of type II diabetic humans (1993) Science, 262, pp. 1441-1444
dc.descriptionAlmind, K., Biorbaek, C., Vestergaard, H., Hansen, T., Echwald, S., Pederson, O., Amino acid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus (1993) Lancet, 342, pp. 828-832
dc.descriptionKahn, C.R., Causes of insulin resistance (1995) Nature, 373, pp. 384-385
dc.descriptionDefronzo, R.A., Hendler, R., Simonson, D.C., Insulin resistance is a prominent feature of insulin-dependent diabetes (1982) Diabetes, 31, pp. 795-801
dc.descriptionMoller, D.E., Flier, J.S., Insulin resistance: Mechanisms, syndromes, and implications (1991) N Engl J Med, 325, pp. 938-948
dc.descriptionMondon, C.E., Reaven, G.M., Evidence of abnormalities of insulin metabolism in rats with spontaneous hypertension (1988) Metabolism, 37, pp. 303-305
dc.descriptionCahill Jr., G.F., Action of adrenal cortex steroids on carbohydrate metabolism (1971) The Human Adrenal Cortex, pp. 205-238. , Christy NP (ed) Harper and Row, New York
dc.descriptionExton, J.H., Miller Jr., T.B., Harper, S.C., Park, C.R., Carbohydrate metabolism in perfused livers of adrenalectomized and steroid-replaced rats (1976) Am J Physiol, 230, pp. 163-170
dc.descriptionO'Brien, R.M., Granner, D.K., PEPCK gene as model of inhibitory effects of insulin on gene expression (1990) Diabetes Care, 13, pp. 327-339
dc.descriptionOlefsky, J.M., Effect of dexamethasone on insulin binding, glucose transport and glucose oxidation of isolated rat adipocytes (1975) J Clin Invest, 56, pp. 1499-1508
dc.descriptionBaxter, J., Forsham, P., Tissue effects of glucocorticoids (1972) Am J Med, 53, pp. 573-577
dc.descriptionRebuffe-Scrive, M., Krotkiewski, M., Elfverson, J., Bjorntorp, P., Muscle and adipose tissue morphology and metabolism in Cushing's syndrome (1988) J Clin Endocrinol Metab, 67, pp. 1122-1128
dc.descriptionCaro, J.F., Amatruda, J.M., Glucocorticoid-induced insulin resistance (1982) J Clin Invest, 69, pp. 866-875
dc.descriptionAmatruda, J.M., Livingston, J.N., Lockwood, D.H., Cellular mechanisms in selected states of insulin resistance: Human obesity, glucocorticoid excess and chronic renal failure (1985) Diabetes Metab Rev, 3, pp. 293-317
dc.descriptionSaad, M.J.A., Folli, F., Kahn, J.A., Kahn, C.R., Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats (1993) J Clin Invest, 92, pp. 2065-2072
dc.descriptionMordes, J.P., Rossint, A.A., Animal models of diabetes mellitus (1985) Joslin's Diabetes Mellitus, pp. 110-137. , Marble A, Krall LP, Bradley RF, Christlieb HR, Soeldner JS (eds) Lea and Febiger, Malvern
dc.descriptionSaad, M.J.A., Araki, E., Miralpeix, M., Rothenberg, P.L., White, M.F., Kahn, C.R., Regulation of insulin receptor substrate 1 in liver and muscle of animal models of insulin resistance (1992) J Clin Invest, 90, pp. 1839-1849
dc.descriptionVicario, P., Brady, E.J., Slater, E., Superstein, R., Insulin receptor tyrosine kinase activity is unaltered in ob/ob and db/db mouse skeletal muscle membranes (1987) Life Sci, 41, pp. 1233-1241
dc.descriptionFolli, F., Saad, J.A., Backer, J.M., Kahn, C.R., Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus (1993) J Clin Invest, 92, pp. 1787-1794
dc.descriptionSaad, M.J.A., Pimenta, W.P., Paccola, G.M.G.F., Picinato, C.E., Foss, M.C., Effect of glucose ingestion on peripheral glucose metabolism in normal man (1989) Diabetes Metab, 15, pp. 5-10
dc.descriptionSaad, M.J.A., Folli, F., Kahn, C.R., Insulin and dexamethasone regulate insulin receptors, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in fao hepatoma cells (1995) Endocrinology, 136, pp. 1579-1588
dc.descriptionSaad, M.J.A., Folli, F., Araki, E., Hashimoto, N., Csermely, P., Kahn, C.R., Regulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in 3R3-F442A adipocytes. Effects of differentiation, insulin and dexamethasone (1994) Mol Endocrinol, 8, pp. 545-557
dc.descriptionFantus, G., Saviolakis, G.A., Hedo, J.A., Gorden, P., Mechanism of glucocorticoid-induced increase in insulin receptors of cultured human lymphocytes (1982) J Biol Chem, 257, pp. 8277-8283
dc.descriptionSalhanick, A.I., Krupp, M.N., Amatruda, J.M., Dexamethasone stimulates insulin receptor synthesis in cultured rat hepatocytes (1983) J Biol Chem, 258, pp. 14130-14135
dc.descriptionRice, K.M., Lienhard, G.E., Garner, C.W., Regulation of the expression of pp160, a putative insulin receptor signal protein, by insulin, dexamethasone, and 1-methyl-3-isobutylxanthine in 3T3-L1 adipocytes (1992) J Biol Chem, 267, pp. 10163-10167
dc.descriptionSavitsky, K., Bar-Shira, A., Gilad, S., A single ataxia telangectasia gene with a product similar to PI 3-kinase (1995) Science, 268, pp. 1749-1753
dc.languageen
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dc.relationActa Diabetologica
dc.rightsfechado
dc.sourceScopus
dc.titleInsulin Receptor/irs-1/pi 3-kinase Signaling System In Corticosteroid-induced Insulin Resistance
dc.typeActas de congresos


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