Activity Of Phosphodiesterases In Granulation Tissue Treated With Electron Irradiation -- Experimental Study On Rats [atividade Das Fosfodiesterases Em Tecido De Granulação Submetido A Irradiação De Elétrons--estudo Experimental Em Ratos.]

dc.creatorBoscolo F.N.
dc.creatorde Almeida S.M.
dc.creatorCury J.A.
dc.creatorLourenco R.M.
dc.date2001
dc.date2015-06-26T14:43:52Z
dc.date2015-11-26T14:17:17Z
dc.date2015-06-26T14:43:52Z
dc.date2015-11-26T14:17:17Z
dc.date.accessioned2018-03-28T21:18:21Z
dc.date.available2018-03-28T21:18:21Z
dc.identifier
dc.identifierPesquisa Odontologica Brasileira = Brazilian Oral Research. , v. 15, n. 3, p. 223 - 228, 2001.
dc.identifier15177491
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0035404810&partnerID=40&md5=ff2023c6e762d465f5f7cc9b479805ed
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/95195
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/95195
dc.identifier2-s2.0-0035404810
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1243292
dc.descriptionThe present study evaluated the effect of low doses of electron radiation on the activity of phosphodiesterases in granulation tissue. In order to induce growth of granulation tissue, a PVC sponge disk was introduced under the dorsal skin of 84 Wistar rats. The rats were divided in two groups, control and irradiated. The enzymatic activity was evaluated according to the evolution of the granulation tissue after 5, 7, 10, 14, 17, 20 and 24 days. Irradiation was carried out 3 days after the implantation of the sponge, by means of a linear accelerator, with energy of 6 MeV, and dose of 1.0 Gy. The results of this study showed that 5'-nucleotidase and ATPase had their activity directly affected by irradiation only in the beginning of the tissue repairing process. Alkaline phosphatase did not suffer any direct effect of irradiation. It is possible that the main factor has been the damage of the cellular components responsible for the growth of granulation tissue, which determine the production of enzymes according to the necessity.
dc.description15
dc.description3
dc.description223
dc.description228
dc.languagept
dc.publisher
dc.relationPesquisa odontologica brasileira = Brazilian oral research
dc.rightsaberto
dc.sourceScopus
dc.titleActivity Of Phosphodiesterases In Granulation Tissue Treated With Electron Irradiation -- Experimental Study On Rats [atividade Das Fosfodiesterases Em Tecido De Granulação Submetido A Irradiação De Elétrons--estudo Experimental Em Ratos.]
dc.typeArtículos de revistas


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