Actas de congresos
Semi-interpenetrating Polymer Networks Of Poly(3-hydroxybutyrate) Prepared By Radiation-induced Polymerization
Registro en:
Radiation Physics And Chemistry. , v. 71, n. 1-2, p. 255 - 260, 2004.
0969806X
10.1016/j.radphyschem.2004.03.049
2-s2.0-4143133318
Autor
Martellini F.
Innocentini Mei L.H.
Lora S.
Carenza M.
Institución
Resumen
Semi-interpenetrating polymer networks (IPNs) based on bacterial poly(3-hydroxy butyrate) with a hydrophilic monomer at different compositions were prepared by radiation-induced polymerization using γ-rays from a 60Co source with a total dose of 10-100kGy. The swelling behaviour was determined by water content at equilibrium, while thermal properties and crystallinity were studied by differential scanning calorimetry. Extraction of the soluble part of PHB from the films at low and high temperature with water or chloroform as well as FTIR data indicate the occurrence of the crosslinking reaction in the hydrogels. The results show a water uptake increasing with the hydrophilic component until 25%. © 2004 Elsevier Ltd. All rights reserved. 71 1-2 255 260 Amass, W., Amass, A., Tighe, B., A review of biodegradable polymers: Uses, current development in the synthesis and characterization of biodegradable polyesters, blends of biodegradable polymers and recent advances in biodegradation studies (1998) Polym. Int., 47, pp. 89-144 Anderson, A.J., Dawes, E.A., Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates (1990) Microbiol. Rev., 54, pp. 450-472 Avella, M., Martuscelli, E., Raimo, M., Properties of blends and composites based on poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate-hydroxyvaleate) (PHBV) copolymers (2000) J. Mater. Sci., 35, pp. 523-545 Carenza, M., Recent achievements in the use of radiation polymerization and grafting for biomedical applications (1992) Radiat. Phys. Chem., 39, pp. 485-493 Gursel, I., Balcik, C., Arica, Y., Akkas, O.N., Hasirci, V., Synthesis and mechanical properties of interpenetrating networks of polyhydroxybutyrate-co-hydroxyvalerate and polyhydroxyethyl methacrylate (1998) Biomaterials, 19, pp. 1137-1143 Hao, J., Deng, X., Semi-interpenetrating networks of bacterial poly(3-hydroxybutyrate) with net-poly(ethylene glycol) (2001) Polymer, 42, pp. 4091-4097 Holland, S.J., Jolly, A.M., Yasin, M., Tighe, B.J., Polymers for biodegradable medical devices. II. Hydroxybutyrate- hydroxyvalerate copolymers: Hydrolytic degradation studies (1987) Biomaterials, 8, pp. 289-295 Kabanov, V.Y., Preparation of polymeric biomaterials with the aid of radiation chemical methods (1998) Russ. Chem. Rev., 67, pp. 783-816 Kaetsu, I., Radiation synthesis of polymeric materials for biomedical and biochemical applications (1993) Adv. Polym. Sci., 105, pp. 81-97 Lee, H.B., Khang, G., Lee, J.H., Polymeric biomaterials (2000) The Biomedical Engineering Handbook, 2nd Edition, 1, pp. 39-41. , Bronzino, J.D. (Ed.), CRC Press, Boca Raton, FL Miller, N.D., Williams, D.F., On the biodegradation of poly β-hydroxybutyrate (PHB) homopolymer and poly β-hydroxybutyrate-hydroxyvalerate copolymers (1987) Biomaterials, 8, pp. 129-137 Mitomo, H., Watanabe, Y., Ishigaki, I., Saito, T., Radiation-induced degradation of poly(3-hydroxybutyrate) and the copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (1994) Polym. Degrad. Stab., 45, pp. 11-17 Mitomo, H., Watanabe, Y., Yoshii, F., Makuuchi, K., Radiation effect on polyesthers (1995) Radiat. Phys. Chem., 46, pp. 233-238 Mitomo, H., Enjoji, T., Watanabe, Y., Yoshii, F., Makuuchi, K., Saito, T., Radiation-induced graft polymerization of poly(3-hydroxybutyrate) and its copolymer (1995) J.M.S. -Pure Appl. Chem., 32, pp. 429-442 Pouton, C.W., Akhtar, S., Biosynthetic polyhydroxyalkanoates and their potential in drug delivery (1996) Adv. Drug Deliv. Rev., 18, pp. 133-162 Uhrich, K.E., Cannizzaro, S.M., Langer, R.S., Shakesheff, K.M., Polymeric systems for controlled drug release (1999) Chem. Rev., 99, pp. 3181-3198 Yasin, M., Holland, S.J., Tighe, B.J., Polymers for biodegradable medical devices. V. Hydroxybutyrate- hydroxyvalerate copolymers: Effects of polymer processing on hydrolytic degradation (1990) Biomaterials, 11, pp. 451-454 Zinn, M., Witholt, B., Egli, T., Occurrence, synthesis and medical application of bacterial polyhydroxyalkanoate (2001) Adv. Drug Deliv. Rev., 53, pp. 5-21