dc.creatorCunha T.S.
dc.creatorTanno A.P.
dc.creatorMoura M.J.C.S.
dc.creatorKlein Marcondes F.
dc.date2005
dc.date2015-06-26T14:08:52Z
dc.date2015-11-26T14:08:28Z
dc.date2015-06-26T14:08:52Z
dc.date2015-11-26T14:08:28Z
dc.date.accessioned2018-03-28T21:09:03Z
dc.date.available2018-03-28T21:09:03Z
dc.identifier
dc.identifierRevista Brasileira De Medicina Do Esporte. , v. 11, n. 3, p. 187 - 192, 2005.
dc.identifier15178692
dc.identifier
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-23144454511&partnerID=40&md5=c942e47148aebaef9ef18bdd61c43fa4
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/93655
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/93655
dc.identifier2-s2.0-23144454511
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1241012
dc.descriptionGlycogen supercompensation is one of the adaptations induced by physical training. To potentiate this phenomenon, many athletes use supraphysiological doses of anabolic androgenic steroids (AAS). The purpose of this study was to evaluate the effects of nandrolone and aerobic physical exercise in rats, on body weight, plasmatic triglycerides levels, blood glucose and glycogen content. Male Wistar rats were randomly divided into 4 groups: Sedentary + vehicle (SV), Trained + vehicle (TV), Sedentary + AAS (SAAS) and Trained + AAS (TAAS) (n = 7-14/group). They received i.m. injections of nandrolone or vehicle for 9 weeks, and during the same period trained rats were submitted to aerobic exercise. Data were analyzed by two-way ANOVA and Tukey tests (p < 0.05). The groups SAAS, TV and TAAS presented lower body weight than the SV group (SAAS: 339 ± 10 = TV: 342 ± 14 = TAAS: 332 ± 6 < SV: 398 ± 9 g). Physical training significantly reduced plasmatic concentration of triglycerides [(TV: 46 ± 4 = TAAS: 44 ± 3) < (SV: 104 ± 1 = SAAS: 101 ± 6 mg/dL)] and of hepatic glycogen [(TV: 3,38 ± 0,57 = TAAS: 2,62 ± 0,34) < (SV: 4,95 ± 0,11 = SAAS: 4,43 ± 0,23 mg/100 mg)] and increased the cardiac glycogen concentration [(TV: 0,38 ± 0,04 = TAAS: 0,42 ± 0,03) > (SV: 0,2 ± 0.02 = SAAS: 0,21 ± 0,02 mg/100 mg)]. Blood glucose and soleus glycogen reserves remained unaltered. The use of supraphysiological doses of nandrolone did not potentiate any of the effects obtained in response to aerobic physical training.
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dc.description187
dc.description192
dc.descriptionPowers, S.K., Howley, E.T., Bioenergética (2000) Fisiologia Do Exercício - Teoria E Aplicação Ao Condicionamento E Ao Desempenho, pp. 21-44. , Powers SK, Howley ET, editores. São Paulo: Manole
dc.descriptionWahren, J., Glucose turnover during exercise in healthy man and in patients with diabetes mellitus (1979) Diabetes, 28, pp. 82-88
dc.descriptionNakatani, A., Han, D., Hansen, P.A., Nolte, L.A., Host, H.H., Hickner, R.C., Effect of endurance exercise training on muscle glycogen supercompensation in rats (1997) J. Appl. Physiol., 82, pp. 711-715
dc.descriptionFoss, M.L., Keteyian, S.J., Medicamentos e recursos ergogênicos (2000) Bases Fisiológicas Do Exercício E Do Esporte, pp. 445-462. , Foss ML, Keteyian SJ, editores. Rio de Janeiro: Guanabara Koogan
dc.descriptionVan Breda, E., Keizer, H.A., Geurten, P., Van Kranenburg, G., Menheere, P.P., Kuipers, H., Modulation of glycogen metabolism of rat skeletal muscles by endurance training and testosterone treatment (1993) Pflugers Arch., 424, pp. 294-300
dc.descriptionCartee, G.D., Young, D.A., Sleeper, M.D., Zierath, J., Wallberg-Henriksson, H., Holloszy, J.O., Prolonged increase in insulin-stimulated glucose transport in muscle after exercise (1989) Am. J. Physiol., 256, pp. 494-499
dc.descriptionParssinen, M., Seppala, T., Steroid use and long-term health risks in former athletes (2002) Sports Med., 32, pp. 83-94
dc.descriptionClarkson, P.M., Thompson, H.S., Drugs and sport (1997) Sports Med., 24, pp. 366-381
dc.descriptionRabkin, J.G., Wagner, G.J., Rabkin, R., A double-blind, placebo-controlled trial of testosterone therapy for HIV-positive men with hypogonadal symptoms (2000) Arch. Gen. Pscychiatry, 57, pp. 141-147
dc.descriptionKuipers, H., Wijnen, J.A., Hartgens, F., Willems, S.M., Influence of anabolic steroids on body composition, blood pressure, lipid profile and liver functions in body builders (1991) Int. J. Sports Med., 12, pp. 413-418
dc.descriptionFranke, W.W., Berendonk, B., Hormonal doping and androgenization of athletes: A secret program of the German Democratic Republic government (1997) Clin. Chem., 43, pp. 1262-1279
dc.descriptionCunha, T.S., Cunha, N.S., Moura, M.J.C.S., Marcondes, F.K., Esteróides anabólicos e a prática desportiva (2004) Braz. J. Pharmac. Sci., 40, pp. 165-179
dc.descriptionGreiwe, J.S., Hickner, R.C., Hansen, P.A., Racette, S.B., Chen, M.M., Holloszy, J.O., Effects of endurance exercise training on muscle glycogen accumulation in humans (1999) J. Appl. Physiol., 87, pp. 222-226
dc.descriptionKawanaka, K., Nolte, L.A., Han, D.H., Hansen, P.A., Holloszy, J.O., Mechanisms underlying impaired GLUT-4 translocation in glycogen-supercompensated muscles of exercised rats (2000) Am. J. Physiol. Endocrinol. Metab., 279, pp. E1311-E1318
dc.descriptionRamamani, A., Aruldhas, M.M., Govindarajulu, P., Differential response of rat skeletal muscle glycogen metabolism to testosterone and estradiol (1999) Can. J. Physiol. Pharmacol., 77, pp. 300-304
dc.descriptionPope Jr., H.G., Katz, D.L., Affective and psychotic symptoms associated with anabolic steroid use (1988) Am. J. Psychiatry, 145, pp. 487-490
dc.descriptionNorton, G.R., Trifunovic, B., Woodiwiss, A.J., Attenuated beta-adrenoceptor-mediated cardiac contractile responses following androgenic steroid administration to sedentary rats (2000) Eur. J. Appl. Physiol., 81, pp. 310-316
dc.descriptionMarcondes, F.K., Vanderlei, L.C.M., Lanza, L.L.B., Spadari-Bratfisch, R.C., Stress-induced subsensitivity to catecholamines depends on the estrous cycle (1996) Can. J. Physiol. Pharmacol., 74, pp. 663-669
dc.descriptionOstman-Smith, I., Adaptative changes in the sympathetic nervous system and some effector organs of the rat following long term exercise or cold acclimation and the role of cardiac sympathetic nerves in the genesis of compensatory cardiac hypertrophy (1979) Acta Physiol. Scand., 477, pp. 1-118
dc.descriptionDubois, M., Gilles, K.A., Hamilton, J.K., Rebers, P.A., Smith, F., Colorimetric method for determination of sugars and related substances (1956) Anal. Chem., 28, pp. 350-356
dc.descriptionLo, S., Russel, J.C., Taylor, A.W., Determination of glycogen in small tissue samples (1970) J. Appl. Physiol., 28, pp. 234-236
dc.descriptionTanno, A.P., Bianchi, F.J., Moura, M.J.C.S., Marcondes, F.K., Atrial supersensitivity to noradrenaline in stressed female rats (2002) Life Sci., 71, pp. 2973-2981
dc.descriptionSpadari, R.C., De Moraes, S., Repeated swimming stress and responsiveness of isolated rat pacemaker to chronotropic effect of noradrenaline and isoprenaline: Role of adrenal corticosteroids (1988) Gen. Pharmacol., 19, pp. 553-557
dc.descriptionSilva, C.A., Polacow, M.L., Guirro, R., Tanno, A.P., Silva, H.C., Paro, D., Tratamento com metformina induz elevação no conteúdo de glicogênio no fígado, nos músculos e nas ilhotas de Langerhans (1999) PUC-SP Ciências Biológicas E Do Ambiente, 1, pp. 53-71
dc.descriptionCoyle, E.F., Metabolismo lipídico durante o exercício (1997) Sports Science Exchange, 15, pp. 20-26
dc.descriptionCarson, J.A., Lee, W.J., Mcclung, J., Hand, G.A., Steroid receptor concentration in aged rat hindlimb muscle: Effect of anabolic steroid administration (2002) J. Appl. Physiol., 93, pp. 242-250
dc.descriptionGuzman, M., Saborido, A., Castro, J., Molano, F., Megias, A., Treatment with anabolic steroids increases the activity of the mitochondrial outer carnitin palmitoyltransferase in rat liver and fast-twitch muscle (1991) Biochem. Pharm., 41, pp. 833-835
dc.descriptionFerguson, M.A., Alderson, N.L., Trost, S.G., Essig, D.A., Burke, J.R., Durstine, J.L., Effects of four different single exercise sessions on lipids, lipoproteins, and lipoprotein lipase (1998) J. Appl. Physiol., 85, pp. 1169-1174
dc.descriptionMarliss, E.B., Kreisman, S.H., Manzon, A., Halter, J.B., Vranic, M., Nessim, S., Gender differences in glucoregulatory responses to intense exercise (2000) J. Appl. Physiol., 88, pp. 457-466
dc.descriptionWahren, J., Felig, P., Hendler, R., Ahlborg, G., Glucose and amino acid metabolism during recovery after exercise (1973) J. Appl. Physiol., 34, pp. 838-845
dc.descriptionBaldwin, K.M., Winder, W.W., Terjung, R.L., Holloszy, J.O., Glycolytic enzymes in different types of skeletal muscle: Adaptation to exercise (1973) Am. J. Physiol., 225, pp. 962-966
dc.descriptionKinney LaPier, T.L., Rodnick, K.J., Effects of aerobic exercise on energy metabolism in the hypertensive rat heart (2001) Phys. Ther., 81, pp. 1006-1017
dc.descriptionGoodwin, G.W., Taegtmeyer, H., Improved energy homeostasis of the heart in the metabolic state of exercise (2000) Am. J. Physiol. Heart Circ. Physiol., 279, pp. H1490-H1501
dc.descriptionSilva, C.A., Polacow, M.L.O., Guirro, R., Tanno, A.P., Silva, H.C., Rodrigues, D., O efeito do fenobarbital sobre as reservas de glicogênio no músculo sóleo desnervado em ratos (1998) Revista Brasileira De Fisioterapia, 3, pp. 35-40
dc.descriptionPloug, T., van Deurs, B., Ai, H., Cushman, S.W., Ralston, E., Analysis of GLUT 4 distribution in whole skeletal muscle fibers: Identification of distinct storage compartments that are recruited by insulin and muscle contractions (1998) J. Cell Biol., 142, pp. 1429-1446
dc.descriptionPrice, T.B., Laurent, D., Petersen, K.F., Rothman, D.L., Shulman, G.I., Glycogen loading alters muscle glycogen resynthesis after exercise (2000) J. Appl. Physiol., 88, pp. 698-704
dc.descriptionPoland, J.L., Poland, J.W., Honey, R.N., Differential response of rat cardiac and skeletal muscle glycogen to glucocorticoids (1982) Can. J. Physiol. Pharmacol., 60, pp. 634-637
dc.descriptionParssinen, M., Kujala, U., Vartiainen, E., Sarna, S., Seppala, T., Increased premature mortality of competitive powerlifters suspected to have used anabolic agents (2000) Int. J. Sports Med., 21, pp. 225-227
dc.languagept
dc.publisher
dc.relationRevista Brasileira de Medicina do Esporte
dc.rightsaberto
dc.sourceScopus
dc.titleRelation Between Anabolic Adrogenic Steroid Administration, Aerobic Physical Training And Glycogen Supercompensation [reflação Entre A Administração De Esteróide Anabólico Androgênico, Treinamento Físico Aeróbio E Supercompensação Do Glicogênio]
dc.typeArtículos de revistas


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