Coagulation And Cancer Therapy: The Potential Of Natural Compounds

dc.creatorJusto G.Z.
dc.creatorFerreira C.V.
dc.date2005
dc.date2015-06-26T14:08:30Z
dc.date2015-11-26T14:08:14Z
dc.date2015-06-26T14:08:30Z
dc.date2015-11-26T14:08:14Z
dc.date.accessioned2018-03-28T21:08:48Z
dc.date.available2018-03-28T21:08:48Z
dc.identifier
dc.identifierCurrent Genomics. , v. 6, n. 6, p. 461 - 469, 2005.
dc.identifier13892029
dc.identifier10.2174/138920205774482981
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-27944454414&partnerID=40&md5=407b8fe78feafabe833490a5c49b70e1
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/93602
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/93602
dc.identifier2-s2.0-27944454414
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1240955
dc.descriptionIn the past few years, it has become clear that the processes of cancer metastasis and invasion are highly dependent on components of the blood coagulation cascade. Metastasis is critically dependent on the formation of new blood vessels and the role of many blood-clotting factors in tumor angiogenesis has been extensively studied. Angiogenesis constitutes an important point in the control of cancer progression and in recent years much attention has been paid to the development of antiangiogenic agents. Natural compounds constitute a promising alternative for application in antiangiogenesis therapy due to their multiple mechanisms of action. Moreover, they can be used as templates for the production of analogues with enhanced activity. In this review, the potential of natural compounds to target blood coagulation cascades and to prevent tumor growth will be highlighted in view of their underlying mechanisms. © 2005 Bentham Science Publishers Ltd.
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dc.descriptionSpek, C.A., Tissue factor, from 'just one of the coagulation factors' to a major player in physiology (2004) Blood Coagul. Fibrinol., 15 (SUPPL. 1), pp. S3-S10
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dc.descriptionBijlsma, M.F., Spek, C.A., Peppelenbosch, M.P., Hedgehog, an unusual signal transducer (2004) Bioessays, 26, pp. 387-394
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dc.descriptionPasquier, E., Honore, S., Pourroy, B., Jordan, M.A., Lehmann, M., Briand, C., Braguer, D., Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells (2005) Cancer Res., 65, pp. 2433-2440
dc.languageen
dc.publisher
dc.relationCurrent Genomics
dc.rightsfechado
dc.sourceScopus
dc.titleCoagulation And Cancer Therapy: The Potential Of Natural Compounds
dc.typeArtículos de revistas


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