Flow microcalorimetric measurements of the antibacterial activity of the homologous series m-alkoxyphenols and p-hydroxybenzoates on Escherichia coli

dc.creatorVolpe, P.L.O
dc.date1997-01-01
dc.date2014-07-17T17:17:57Z
dc.date2015-11-26T13:54:28Z
dc.date2014-07-17T17:17:57Z
dc.date2015-11-26T13:54:28Z
dc.date.accessioned2018-03-28T21:06:18Z
dc.date.available2018-03-28T21:06:18Z
dc.identifierJournal of the Brazilian Chemical Society. Sociedade Brasileira de Química, v. 8, n. 4, p. 1-6, 1997.
dc.identifier0103-5053
dc.identifierS0103-50531997000400005
dc.identifier10.1590/S0103-50531997000400005
dc.identifierhttp://dx.doi.org/10.1590/S0103-50531997000400005
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50531997000400005
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/25076
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/25076
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1240301
dc.descriptionAntibacterial activity of two homologous series (m-alkoxyphenols and p-hydroxybenzoates) was studied in vitro by the respiration of Escherichia coli using flow microcalorimetry. Results for both series showed a linear relationship between log(dose) and the calorimetric response (CR). Analysis of the data allowed the identification of contributions for the derived bioactivity from the parent structures (the molecule minus n-CH2 groups present in the side-chain) and the lipophilic groups, CH2.
dc.descriptionA atividade antibacteriana dos membros de duas séries homólogas (m-alcoxifenóis e p-hidroxibenzoatos de alquila) foi estudada in vitro sobre a respiração da Escherichia coli usando microcalorimetria de fluxo. Os resultados para ambas as séries mostraram uma relação linear entre log(dose) e a resposta calorimétrica (RC). Análise dos dados permitiu a identificação de contribuições de bioatividade concernente a estrutura matriz (a molécula menos os grupos n-CH2 presentes na cadeia lateral) e a grupos lipofílicos, CH2.
dc.description1
dc.description6
dc.languageen
dc.publisherSociedade Brasileira de Química
dc.relationJournal of the Brazilian Chemical Society
dc.rightsaberto
dc.sourceSciELO
dc.subjectbiological microcalorimetry
dc.subjectcalorimetric response
dc.subjecthomologous series
dc.titleFlow microcalorimetric measurements of the antibacterial activity of the homologous series m-alkoxyphenols and p-hydroxybenzoates on Escherichia coli
dc.typeArtículos de revistas


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