Protein tyrosine phosphatases: properties and biological functions

dc.creatorAoyama, Hiroshi
dc.creatorSilva, Telma Maria Araújo
dc.creatorMiranda, Márcio André
dc.creatorFerreira, Carmen Veríssima
dc.date2003-12-01
dc.date2014-07-17T14:51:47Z
dc.date2015-11-25T20:06:03Z
dc.date2014-07-17T14:51:47Z
dc.date2015-11-25T20:06:03Z
dc.date.accessioned2018-03-28T20:37:16Z
dc.date.available2018-03-28T20:37:16Z
dc.identifierQuímica Nova. Sociedade Brasileira de Química, v. 26, n. 6, p. 896-900, 2003.
dc.identifier0100-4042
dc.identifierS0100-40422003000600019
dc.identifier10.1590/S0100-40422003000600019
dc.identifierhttp://dx.doi.org/10.1590/S0100-40422003000600019
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000600019
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/23593
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/23593
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1232801
dc.descriptionProtein phosphorylation-dephosphorylation catalyzed by the opposing and dynamic action of protein kinases and phosphatases probably, is the most crucial chemical reaction taking place in living organisms. Protein phosphatases are classified according to their substrate specificity and sensitivity to inhibitory or activator agents, into two families of protein phosphatases: serine/threonine phosphatases and tyrosine phosphatases (PTPs). PTPs can be divided into 3 groups: tyrosine specific phosphatases, dual and low molecular weight phosphatases. The role of tyrosine phosphorylation in mitogenic signaling is well documented, and one would predict that vanadate, pervanadate and other oxidant agents (protein tyrosine phosphatase inhibitors) may act as a growth stimulator.
dc.description896
dc.description900
dc.languagept
dc.publisherSociedade Brasileira de Química
dc.relationQuímica Nova
dc.rightsaberto
dc.sourceSciELO
dc.subjectprotein tyrosine phosphatases
dc.subjectsignal transduction
dc.subjectbiological function
dc.titleProteínas tirosina fosfatases: propriedades e funções biológicas
dc.titleProtein tyrosine phosphatases: properties and biological functions
dc.typeArtículos de revistas


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