Use Of Phthalimide And/or Sulphonamide Derivatives In The Treatment Of Diseases Which Require Reducing The Tnf-alpha Levels And An Exogenous Source Of Nitric Oxide, Phthalimide Derivatives, Sulphonamide Derivatives, And A Method For Obtaining A Sulphonamide Derivative

dc.creatorDos Santos Jean Leandro [br]
dc.creatorChung Man Chin [br]
dc.creatorMoreira Lima Lidia [br]
dc.creatorFerreira Costa Fernando [br]
dc.creatorLanaro Carolina [br]
dc.date2012-09-27
dc.date2015-02-09T18:29:54Z
dc.date2015-02-09T18:29:54Z
dc.date24/02/2012
dc.date.accessioned2018-03-28T20:29:23Z
dc.date.available2018-03-28T20:29:23Z
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/84837
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1230695
dc.descriptionPreparation and use of phthalimide and/or sulphonamide derivatives with nitric oxide donor properties, having activities in increasing gamma-globin gene expression and anti-inflammatory and analgesic activities, effective in the treatment of hematologic diseases which require reducing the TNF-a leveis and an exogenous source of nitric oxide, such as sickle-cell disease. The functionalized phthalimide derivatives are designed from the prototypes thalidomide and hydroxyurea.
dc.descriptionUS2012245364 (A1); US8338474 (B2)
dc.descriptionC07D209/48
dc.description
dc.descriptionUS201213404777
dc.descriptionC07D209/48
dc.rightsaberto
dc.titleUse Of Phthalimide And/or Sulphonamide Derivatives In The Treatment Of Diseases Which Require Reducing The Tnf-alpha Levels And An Exogenous Source Of Nitric Oxide, Phthalimide Derivatives, Sulphonamide Derivatives, And A Method For Obtaining A Sulphonamide Derivative
dc.typePatentes


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