Determinar la prevalencia del uso de corticosteroides prenatales en las mujeres que dieron a luz prematuramente en 3 condados de América Latina y para evaluar las características maternas asociadas con el uso. Un estudio multicéntrico, prospectivo, descriptivo fue realizado en 4 hospitales en Ecuador, 5 en Uruguay, y 3 en ​​El Salvador entre 2004 y 2008. Las mujeres que habían dado a luz entre las 24 y las 34 semanas de embarazo respondieron a un cuestionario de evaluación de las características sociodemográficas, antecedentes obstétricos, atención prenatal, las actitudes de las mujeres a los servicios de salud y el conocimiento de los factores de riesgo prematuros, la administración de corticosteroides prenatales, y las características de la entrega y el recién nacido. La asociación entre el uso de corticosteroides prenatales y las variables del estudio se evaluó a través de un análisis de regresión logística basado en un modelo jerárquico. Un total de 1.062 mujeres que tuvieron un parto prematuro se incluyeron en el estudio. El uso de corticosteroides prenatales fue 34,8% (IC del 95%, 29,9% -39,9%) en el Ecuador, el 54,6% (IC del 95%, 49,6% -59,6%) en El Salvador, y el 71,0% (IC del 95%, 65,3% -76,2% ) en Uruguay. Hospital de tiempo-admisión hasta la entrega se asoció con el uso de corticosteroides prenatales en todos los 3 países. El estudio reveló un patrón variado de uso de corticosteroides prenatales a través de los 3 países, y una diversidad de factores que influyen.Background: Antenatal corticosteroids administered to women at risk of preterm birth is an intervention which has been proved to reduce the risk of respiratory distress syndrome, intraventricular hemorrhage, and neonatal mortality. There is a significant gap in the literature regarding the prevalence of the use of antenatal corticosteroids in Latin American countries and the attitudes and opinions of providers regarding this practice. The aim of this study was to assess the knowledge, attitudes and practices of health care providers regarding the use of antenatal corticosteroids in women at risk of preterm birth in Latin America. Methods: This was a multicenter, prospective, descriptive study conducted in maternity hospitals in Ecuador, El Salvador, Mexico and Uruguay. Physicians and midwives who provide prenatal care or intrapartum care for women delivering in the selected hospitals were approached using a self-administered questionnaire. Descriptive statistics was used. Results: The percentage of use of ACT in threatened preterm labour (TPL) reported by providers varies from 70% in Mexico to 97% in Ecuador. However, 60% to 20% of the providers mentioned that they would not use this medication in women at risk and would limit its use when there was a threatened preterm labour. In only one country recommended regimens of antenatal corticosteroids are followed by around 90% of providers whereas in the other three countries recommended regimens are followed by only 21%, 61%, 69% of providers. Around 40% of providers mentioned that they would administer a new dose of corticosteroids again, regardless the patient already receiving an entire regimen. Between 11% and 35% of providers, according to the countries, mentioned that they do not have adequate information on the correct use of this medication. Conclusions: This study shows that the use of this intervention could be improved by increasing the knowledge of Latin American providers on its indications, benefits, and regimens.vol. 108; no. 1