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Mostrando ítems 11-20 de 45
Efecto de la alta presión hidrostática en la exposición del contenido de sulfhidrilos libres en amilasa fúngica = Effect of high hydrostatic pressure on free sulfhydryl content from fungal α-amylase
(2018-06)
El objetivo de este trabajo fue evaluar el efecto térmico residual generado luego del uso en ciclos consecutivos del equipo de Alta Presión Hidrostática (APH) en tres posiciones internas (superior, central e inferior) ...
Resposta da levedura Saccharomyces cerevisiae ao estresse oxidativo induzido pelo cádmio
(Universidade Federal de Minas GeraisUFMG, 2011-09-12)
Cadmium (Cd2+) is a non-redox metal capable of generating free radicals by an indirect way, by depletion of antioxidant defenses and these way increased oxidative stress, particularly binding sulfhydryl groups, these groups ...
Plastidic Phosphoglycerate Kinase from Phaeodactylum tricornutum: On the Critical Role of Cysteine Residues for the Enzyme Function
(Elsevier Gmbh, 2012-03)
Chloroplastidic phosphoglycerate kinase (PGKase) plays a key role in photosynthetic organisms, catalyzing a key step in the Calvin cycle. We performed the molecular cloning of the gene encoding chloroplastidic PGKase-1 in ...
Quercetin antagonism of GABAAρ1 receptors is prevented by ascorbic acid through a redox-independent mechanism
(Elsevier, 2013-08)
Quercetin is a natural flavonoid widely distributed in plants that acts as a neuroprotective agent and modulates the activity of different synaptic receptors and ion channels, including the ionotropic GABA receptors. ...
An intracellular redox sensor for reactive oxygen species at the M3-M4 linker of GABAArho1 receptors
(Wiley, 2014-04-11)
Background and Purpose: Reactive oxygen species (ROS) are normally involved in cell oxidative stress but also play a role as cellular messengers in redox signalling; for example, modulating the activity of neurotransmitter ...
Avaliação dos efeitos farmacológico e toxicológico de 4- organocalcogeno-isoquinolinas
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2014-03-12)
Monoamine oxidase (MAO) is a target enzyme in the treatment of several
pathologies, being that new molecules which inhibit of a selective, potent and
reversible manner their isoforms and without adverse effects are ...
Nitric oxide potentiation of the homomeric ρ1 GABAC receptor function
(Wiley Blackwell Publishing, Inc, 2012-11)
BACKGROUND AND PURPOSE NO is a highly diffusible and reactive gas produced in the nervous system, which acts as a neuronal signal mediating physiological or pathological mechanisms. NO can modulate the activity of ...
Identification of cysteines involved in S-nitrosylation, S-glutathionylation, and oxidation to disulfides in ryanodine receptor type 1
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2006-12-29)
The skeletal muscle Ca2+-release channel ( ryanodine receptor type 1 (RyR1)) is a redox sensor, susceptible to reversible S-nitrosylation, S-glutathionylation, and disulfide oxidation. So far, Cys-3635 remains the only ...
Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome
(WILEY-BLACKWELL, 2008)
The yeast 20S proteasome is subject to sulfhydryl redox alterations, such as the oxidation of cysteine residues (Cys-SH) into cysteine sulfenic acid (Cys-SOH), followed by S-glutathionylation (Cys-S-SG). Proteasome ...